


Bioderma Sensibio Defensive Serum
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A long-lasting soothing moisturizing concentrate designed to support sensitive skin and help protect against the visible effects of daily external aggressions.
Sensibio Defensive Serum is a lightweight, milky serum created for sensitive and sensitized skin experiencing discomfort, dehydration, and early visible signs of aging. Formulated with Bioderma’s Defensive Technology, this fragrance-free serum helps soothe the skin, support the moisture barrier, and revive radiance while helping reduce the appearance of fine lines and wrinkles over time. With its comfortable texture and very good tolerance, it fits beautifully into a daily routine for skin that needs both calm and care.
Benefits:
- Helps reduce the appearance of wrinkles and fine lines
- Immediately soothes sensitive skin
- Provides 24-hour hydration
- Helps revive the look of radiance
- Supports the skin’s moisture barrier
- Lightweight, milky texture
- Fragrance-free and tested under dermatological control
How to Use:
- Apply morning and evening to the face and neck
- Use on clean skin
- Follow with your moisturizer
- For a complete routine, pair with Bioderma Sensibio cleansing essentials
Loshen & Crem’s Recommendation:
Sensibio Defensive Serum is a beautiful option for skin that feels reactive, dehydrated, or visibly tired from daily stressors. Its lightweight texture makes it especially easy to layer, while the formula helps support comfort, hydration, and a fresher-looking complexion over time. Pair it with Sensibio Defensive or Sensibio Defensive Rich for a more complete routine centered around soothing and barrier support.
Ingredients:
Key Ingredients:
- Defensive Technology: Helps support sensitive skin by addressing the visible effects of external aggressions and helping reinforce the skin’s defenses.
- Carnosine: An antioxidant that helps protect the skin from external stressors that can contribute to dryness and visible aging.
- Vitamin E: Helps provide antioxidant support and comfort for stressed skin.
- Palmitoyl Tetrapeptide-10: Helps support the skin’s moisture barrier and improve skin resilience.
- Salvia Miltiorrhiza Root Extract: Helps soothe the skin and reduce the look of reactivity.
- Hydrolyzed Hyaluronic Acid: Helps provide lightweight hydration for smoother, plumper-looking skin.
- Fucose Polymer: Helps support skin comfort and resistance.
Full Ingredients List:
Aqua/Water/Eau, Glycerin, Butylene Glycol, C15-19 Alkane, Squalane, Cellulose, C20-22 Alkyl Phosphate, C20-22 Alcohols, Pentylene Glycol, 1,2-Hexanediol, Caprylyl Glycol, Carnosine, Polyacrylate Crosspolymer-6, Maltodextrin, Xanthan Gum, Mannitol, Xylitol, Tocopherol, Salvia Miltiorrhiza Root Extract, Rhamnose, Biosaccharide Gum-1, Citric Acid, Glycine Soja (Soybean) Oil, Hydrolyzed Hyaluronic Acid, Sodium Hydroxide, Palmitoyl Tetrapeptide-10.
Free Express Shipping with orders over $199
Available at our Edmonton Boutique
Ship to Canada only
Pickup currently unavailable at Loshen & Crem

Bioderma Sensibio Defensive Serum
30 ml
Loshen & Crem
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
Returns & Refunds
At Loshen & Crem, we understand that sometimes, even the most carefully chosen product might not be "the one."
- Returns: You have 30 days from delivery to return any unopened and unused products in perfect condition—just as they arrived.
- Refunds: If your return reaches us within 30 days of purchase, you’ll have the choice between a refund or store credit (your preference, naturellement). After 30 days, store credit is your only option. Beyond 40 days, refunds and credits are no longer possible.
Final Sale Items
For transparency, certain items are final sale and not eligible for return or exchange:
- Products on sale
- Products marked “Final markdown” on our online store
- Gift cards
- Promotional kits and deluxe samples
- Limited-edition or seasonal item
Shipping Policy
At Loshen & Crem, we take delivering your skincare treasures très seriously. From Canada to the U.S., we’re here to ensure your beauty cabinet is always well-stocked.
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Free Shipping:
- Canada: Complimentary EXPRESS shipping on orders over $199 CAD (after discounts and before taxes).
- United States: Complimentary EXPRESS shipping on orders over $250 USD. We are temporarily pausing USD payments at the moment. Apologies for the inconvenience, and thank you for your understanding!
- During our annual sales, enjoy free EXPEDITED shipping for orders over $250 CAD (or $350 USD).
- For smaller indulgences, shipping is $24.95 CAD within Canada and $30.95 USD to the U.S.
P.S. We ship to P.O. Boxes via Canada Post—but not during strikes. C’est compliqué.
Processing Time:
We aim to dispatch your order within 2 business days, though peak sales and payment verifications may require a touch more patience.
Please note that if you make any changes with the courier after the dispatch, our carrier will charge a $32 fee. In addition, we will have to withdraw the Free Express shipping option from your SkinSkinGlow points account. We appreciate your understanding.
Our processing time starts from the moment your order is successfully submitted and may take up to 2 business days to dispatch your order. However, please be aware that processing and handling time may be extended during peak sale periods. Before we can ship your order, we may need to hold your order for payment verification and confirm your details with your card issuer.
We will do our very best to minimize delays.
Shipping Rates & Delivery Times
Estimated Delivery Times (Canada):
- British Columbia & Alberta: 1–2 business days
- Manitoba & Saskatchewan: 1–2 business days
- Quebec & Ontario: 1–2 business days
- Atlantic Provinces: 1–3 business days
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United States: Delivery times vary by region:
- Zone 1: Eastern States – 3–4 business days
- Zone 2: Central States – 4–5 business days
- Zone 3: Western States – 5 business days
Remote areas may experience longer shipping times.Please Note: Shipping windows are estimates and not guarantees. Delays may occur due to weather, traffic, or additional verification processes.
Shipping Address Details
For a smooth delivery, please provide all relevant information, including buzzer codes, directional suffixes (North, South, etc.), or special instructions.
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Address Changes: Once your package has left our warehouse, address updates cannot be made. If you need to make changes before dispatch, email us at info@loshen.ca with your order details.
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Carrier Fees: Any changes made with the courier after dispatch will incur a $32 CAD fee, and the Free Express Shipping option will be deducted from your La Crème Points account.
Tracking Your Order
All shipments include tracking information, so you can follow your package from our warehouse to your door. A confirmation email with your tracking number will be sent once your order is dispatched.
Damaged or Lost Packages
- Damaged Parcels: If your order arrives damaged, please contact us at info@loshen.ca with photos and details. We’ll work to resolve the issue promptly.
- Lost or Stolen Packages: If your package is marked "delivered" but hasn’t arrived, please contact the carrier directly to file a claim.
Tips to Avoid Lost or Stolen Packages:
- Opt for a signature upon receipt (required for orders over $350 CAD).
- Have your package delivered to your workplace.
- If you’re not home on the expected delivery date, ask a neighbor to receive your package.
Unclaimed Parcels
If your package is returned to us unclaimed, we’ll issue a refund minus a $24.95 CAD return shipping fee.
Free Samples
We believe every order deserves a little extra care! Expect 1–3 complimentary samples selected by our Skincare Specialists to perfectly complement your order.
Loyalty Rewards: La Crem Points
Earn La Crème Points with every purchase and redeem them for future orders. From time to time, we also offer Free Gifts With Purchase (GWP) for select brands, but these are available only while supplies last.
At Loshen & Crem, we aim to deliver excellence at every step of your skincare journey, with care and a touch of elegance. Questions? Don’t hesitate to reach out—we’re always happy to assist!
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