Your routine
GlyMed PlusComfort Cream with Aloe Vera
Why it fits
A light yet deeply nourishing moisturizer designed to hydrate, soothe and protect dry, reactive or sensitized-feeling skin.
GlyMed Plus Firming Serum
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Explore La Crem rewardsA multi-tasking powerhouse serum designed to lift, firm, and brighten while reducing fine lines and evening out skin tone.
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Boutique details
Your Edmonton boutique.
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Standard free $149 CAD+ · Priority free $249 CAD+ on eligible orders
Standard free $149 CAD+ · Priority upgrade $30 CAD
This item excludes the entire order from free Priority, including orders of $249 CAD or more. The paid upgrade is offered where available.
Delivery details
For delivery in Canada: Standard is $25 CAD below $149 CAD. Priority is $30 CAD below $249 CAD and free from $249 CAD on eligible orders. Adding an item excluded from free Priority removes free Priority for the entire order.
This selected item excludes the entire order from free Priority shipping in Canada. Standard is $25 CAD below $149 CAD and free from $149 CAD. A paid Priority upgrade is $30 CAD where available, including orders of $249 CAD or more.
Thresholds apply after discounts, before taxes and shipping. Product, ground-shipping and destination restrictions may apply. Available services and final charges appear at checkout.
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Selected with care.
GlyMed Plus
Firming Serum
Your ritual begins with the right choice.
$198.50 CAD
Taxes calculated at checkout.
The skincare focus
GlyMed Plus Firming Serum
A multi-tasking powerhouse serum designed to lift, firm, and brighten while reducing fine lines and evening out skin tone.
Explore our ingredient glossaryGlyMed Plus
The formula, explained.
The ingredients behind this formula—and what they bring to your skin.
Apple (Malus Domestica) Stem Cells
A natural AHA with soothing and antioxidant benefits, promoting gentle exfoliation and skin renewal.
1-Methylhydantoin-2-Imide
A brightening active that helps reduce the look of pigmentation and even skin tone.
Dipeptide Diaminobutyroyl Benzylamide Diacetate
A peptide that helps smooth the look of expression lines.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Pairs beautifully.
Explore another step in your face-care routine.
Your routine
GlyMed PlusMega Cream Cleanser
Why it fits
GlyMed Plus Mega Cream Cleanser is an ultra-gentle cream cleanser that effectively dissolves makeup and oil, providing a deep, yet soothing and hydrating cleanse. It is designed to be both thorough and gentle, ensuring that the skin is left clean, soft, and moisturized.
Worth knowing
The finer details.
A closer look at your skin, your routine and what goes into the formula.
GlyMed Plus Firming Serum
A multi-tasking powerhouse serum designed to lift, firm, and brighten while reducing fine lines and evening out skin tone. This advanced formula features plant stem cells, biopeptides, and brightening actives to help skin look firmer and more lifted and to reduce the look of uneven pigmentation. Powered by Apple Stem Cells, Squalane, and Citric Acid, this serum supports smoother, more elastic-looking skin and provides antioxidant care. Ideal for all skin types, including sensitive and pregnancy-safe, it helps restore a youthful, lifted appearance.
Benefits
- Lifts and firms sagging skin for a sculpted appearance
- Helps skin look firmer, more elastic and more resilient
- Brightens and evens skin tone by reducing the look of dark spots
- Reduces the look of fine lines and wrinkles for a smoother texture
- Pregnancy-safe and suitable for sensitive skin
- Can be used as an eye serum to target signs of aging around the eyes
How to use
- After cleansing and toning, apply 1 pump to face, neck, and chest in the morning and evening.
- Follow with your moisturizer and SPF in the AM for added protection.
- Can be layered with other serums for enhanced results.
- ✨ Pro Tip: This serum works beautifully as an eye serum, helping to firm, brighten, and smooth fine lines around the delicate eye area.
Full Ingredient List
Aqua (Water), Glycerin, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Squalane, Polysorbate 20, Creatine, 1-Methylhydantoin-2-Imide, Sodium Ascorbyl Phosphate, Sodium PCA, Malus Domestica (Uttwiler Spatlauber Apple) Fruit Cell Culture Extract, Myristoyl Pentapeptide-11, Myristoyl Pentapeptide-8, Palmitoyl Pentapeptide-4, Sodium Hyaluronate, Biosaccharide Gum-1, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Folic Acid, Lecithin, Cyclopentasiloxane, Cyclohexasiloxane, Butylene Glycol, Chondrus Crispus (Carrageenan), Propylene Glycol, Citric Acid, Polysorbate 60, Phenoxyethanol, Xanthan Gum, Carbomer, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Disodium EDTA.
Shipping & returns
For delivery and return information, view our policy.
A multi-tasking powerhouse serum designed to lift, firm, and brighten while reducing fine lines and evening out skin tone. This advanced formula features plant stem cells, biopeptides, and brightening actives to help skin look firmer and more lifted and to reduce the look of uneven pigmentation. Powered by Apple Stem Cells, Squalane, and Citric Acid, this serum supports smoother, more elastic-looking skin and provides antioxidant care. Ideal for all skin types, including sensitive and pregnancy-safe, it helps restore a youthful, lifted appearance.
Benefits
- Lifts and firms sagging skin for a sculpted appearance
- Helps skin look firmer, more elastic and more resilient
- Brightens and evens skin tone by reducing the look of dark spots
- Reduces the look of fine lines and wrinkles for a smoother texture
- Pregnancy-safe and suitable for sensitive skin
- Can be used as an eye serum to target signs of aging around the eyes
Loshen’s Recommendation
If you need one serum that does it all—firming, brightening, and smoothing—this is it. It’s perfect for lifting sagging skin, reducing fine lines, and targeting pigmentation all in one step. We love using it as both a face and eye serum for a complete anti-aging boost!
How to Use
- After cleansing and toning, apply 1 pump to face, neck, and chest in the morning and evening.
- Follow with your moisturizer and SPF in the AM for added protection.
- Can be layered with other serums for enhanced results.
✨ Pro Tip: This serum works beautifully as an eye serum, helping to firm, brighten, and smooth fine lines around the delicate eye area.
Ingredients
- Apple (Malus Domestica) Stem Cells – A natural AHA with soothing and antioxidant benefits, promoting gentle exfoliation and skin renewal.
- 1-Methylhydantoin-2-Imide – A brightening active that helps reduce the look of pigmentation and even skin tone.
- Dipeptide Diaminobutyroyl Benzylamide Diacetate – A peptide that helps smooth the look of expression lines.
- Myristoyl Pentapeptide-11 & Pentapeptide-8 – Biopeptides that help skin look firmer and smoother.
- Citric Acid – A fruit-derived antioxidant and AHA that supports skin renewal and helps defend against environmental stressors.
- Squalane – Mimics the skin’s natural oils, deeply hydrating while balancing sebum production.
Full Ingredients List
Aqua (Water), Glycerin, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Squalane, Polysorbate 20, Creatine, 1-Methylhydantoin-2-Imide, Sodium Ascorbyl Phosphate, Sodium PCA, Malus Domestica (Uttwiler Spatlauber Apple) Fruit Cell Culture Extract, Myristoyl Pentapeptide-11, Myristoyl Pentapeptide-8, Palmitoyl Pentapeptide-4, Sodium Hyaluronate, Biosaccharide Gum-1, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Folic Acid, Lecithin, Cyclopentasiloxane, Cyclohexasiloxane, Butylene Glycol, Chondrus Crispus (Carrageenan), Propylene Glycol, Citric Acid, Polysorbate 60, Phenoxyethanol, Xanthan Gum, Carbomer, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Disodium EDTA.
The care behind your order
From our boutique.
To your door.
A few helpful details, before your next delivery.
Track your orderDelivery
A good thing, on its way.
Delivery details
For delivery in Canada: Standard is $25 CAD below $149 CAD. Priority is $30 CAD below $249 CAD and free from $249 CAD on eligible orders. Adding an item excluded from free Priority removes free Priority for the entire order.
This selected item excludes the entire order from free Priority shipping in Canada. Standard is $25 CAD below $149 CAD and free from $149 CAD. A paid Priority upgrade is $30 CAD where available, including orders of $249 CAD or more.
Thresholds apply after discounts, before taxes and shipping. Product, ground-shipping and destination restrictions may apply. Available services and final charges appear at checkout.
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Collect in Edmonton.
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Here after checkout, too.
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Apple (Malus Domestica) Stem Cells
A natural AHA with soothing and antioxidant benefits, promoting gentle exfoliation and skin renewal.
1-Methylhydantoin-2-Imide
A brightening active that helps reduce the look of pigmentation and even skin tone.
Dipeptide Diaminobutyroyl Benzylamide Diacetate
A peptide that helps smooth the look of expression lines.
Myristoyl Pentapeptide-11 & Pentapeptide-8
Biopeptides that help skin look firmer and smoother.
Citric Acid
A fruit-derived antioxidant and AHA that supports skin renewal and helps defend against environmental stressors.
Squalane
Mimics the skin’s natural oils, deeply hydrating while balancing sebum production.
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Your skin.
Our attention.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.Personal guidance, in Edmonton or online.
The care behind your care
A place in your routine.
A team in your corner.
From your first question to your next replenishment, there’s a real person here to help.
01 Make sense of what you already use
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our team02 Get to know your skin
Take our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting point03 Keep the conversation going
A question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Explore GlyMed Plus.
Find your place to begin.
Discover GlyMed Plus Firming Serum at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the GlyMed Plus collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
Your ritual, beautifully noted.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.