Your routine
BiophoraCalming Cleanser
Why it fits
A pH-balanced cleanser that respects the barrier while your skin gets used to retinol.

Skincare Boutique & Facial Institute
Skincare Boutique & Facial Institute
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Explore La Crem rewardsBiophora’s gentle 0.3% encapsulated retinol cream, a professional first step into retinol for normal to oily skin. Evening only.
Discover the formula & ingredientsPickup in Edmonton
Usually ready in 24 hours
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Let’s talk about your skin and what belongs in your routine.
From our boutique to your door
For delivery in Canada: Standard is $25 CAD below $149 CAD. Priority is $30 CAD below $249 CAD and free from $249 CAD on eligible orders. Adding an item excluded from free Priority removes free Priority for the entire order.
This selected item excludes the entire order from free Priority shipping in Canada. Standard is $25 CAD below $149 CAD and free from $149 CAD. A paid Priority upgrade is $30 CAD where available, including orders of $249 CAD or more.
Thresholds apply after discounts, before taxes and shipping. Product, ground-shipping and destination restrictions may apply. Available services and final charges appear at checkout.
Selected with care.
Biophora
Your ritual begins with the right choice.
$98.00 CAD
Taxes calculated at checkout.
The skincare focus
Biophora’s gentle 0.3% encapsulated retinol cream, a professional first step into retinol for normal to oily skin. Evening only.
Explore our ingredient glossaryBiophora
The ingredients behind this formula—and what they bring to your skin.
Encapsulated retinol (0.3%)
An encapsulated form of vitamin A that releases gradually, to help the look of texture, tone and fine lines with less redness and irritation.
Squalane
Hydrates, softens and protects the skin barrier, offsetting the dryness often associated with retinol.
Vitamin E
Tocopherol, an antioxidant that helps soothe the skin and protect it from everyday environmental stress.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Your routine
A pH-balanced cleanser that respects the barrier while your skin gets used to retinol.
Your routine
Biophora’s lightweight calming hydration serum for skin that feels dry, tight or reactive. Morning and evening, after cleansing and toning.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
Biophora’s gentle 0.3% encapsulated retinol cream, a professional first step into retinol for normal to oily skin. Evening only.
Where we start most clients who are new to retinol. The encapsulated retinol releases gradually, so you get the renewing effect of vitamin A with far less redness, dryness and peeling. Used consistently, skin looks smoother, clearer and more even, with softer-looking fine lines, while squalane and vitamin E keep the barrier comfortable through our dry winters.
Our recommendation: If you would like help introducing this product into your routine, we recommend a complimentary virtual consultation with one of our estheticians.
Aqua (water), Caprylic capric triglyceride, Mineral oil, Glyceryl Stearate, PEG-100 Stearate, Squalane, Propylene glycol, Dimethicone, Dipropylene glycol, Betula alba bark extract, Scrophularia nodosa extract, Retinol, BHT, Tricaprylin, Polymethyl methacrylate, PEG-40 hydrogenated castor oil, Tocopherol, Phenoxyethanol, Ethylhexylglycerin, Cetyl alcohol, Stearyl alcohol, Carbomer, Disodium EDTA.
For delivery and return information, view our policy.
Biophora’s gentle 0.3% encapsulated retinol cream, a professional first step into retinol for normal to oily skin. Evening only.
Where we start most clients who are new to retinol. The encapsulated retinol releases gradually, so you get the renewing effect of vitamin A with far less redness, dryness and peeling. Used consistently, skin looks smoother, clearer and more even, with softer-looking fine lines, while squalane and vitamin E keep the barrier comfortable through our dry winters.
Our recommendation: If you would like help introducing this product into your routine, we recommend a complimentary virtual consultation with one of our estheticians.
Retinol makes the skin more sensitive to the sun: wear a broad-spectrum SPF every day while using it. Retinol is a form of vitamin A. If you are pregnant, breastfeeding or planning a pregnancy, check with your healthcare provider before use.
Aqua (water), Caprylic capric triglyceride, Mineral oil, Glyceryl Stearate, PEG-100 Stearate, Squalane, Propylene glycol, Dimethicone, Dipropylene glycol, Betula alba bark extract, Scrophularia nodosa extract, Retinol, BHT, Tricaprylin, Polymethyl methacrylate, PEG-40 hydrogenated castor oil, Tocopherol, Phenoxyethanol, Ethylhexylglycerin, Cetyl alcohol, Stearyl alcohol, Carbomer, Disodium EDTA.
The care behind your order
A few helpful details, before your next delivery.
Track your orderDelivery
For delivery in Canada: Standard is $25 CAD below $149 CAD. Priority is $30 CAD below $249 CAD and free from $249 CAD on eligible orders. Adding an item excluded from free Priority removes free Priority for the entire order.
This selected item excludes the entire order from free Priority shipping in Canada. Standard is $25 CAD below $149 CAD and free from $149 CAD. A paid Priority upgrade is $30 CAD where available, including orders of $249 CAD or more.
Thresholds apply after discounts, before taxes and shipping. Product, ground-shipping and destination restrictions may apply. Available services and final charges appear at checkout.
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
An encapsulated form of vitamin A that releases gradually, to help the look of texture, tone and fine lines with less redness and irritation.
Hydrates, softens and protects the skin barrier, offsetting the dryness often associated with retinol.
Tocopherol, an antioxidant that helps soothe the skin and protect it from everyday environmental stress.
Betula alba bark extract, known for its calming and purifying properties.
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Biophora Bioactive Retinol 30 at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Biophora collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.
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