Your routine
NeoGenesisBarrier Renewal Cream
Why it fits
NeoGenesis Barrier Renewal Cream is a lightweight, deeply hydrating formula designed to restore and strengthen the skin barrier.
NeoGenesis Skin Serum
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Explore La Crem rewardsNeoGenesis Skin Serum is an advanced, all-in-one daily serum powered by patented S²RM® technology to deliver vital nutrients that support skin health, hydration, and resilience.
Discover the formula & ingredientsPickup in Edmonton
Usually ready in 24 hours
Boutique details
Your Edmonton boutique.
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Shipping options
Standard free $149 CAD+ · Priority free $249 CAD+ on eligible orders
Standard free $149 CAD+ · Priority upgrade $30 CAD
This item excludes the entire order from free Priority, including orders of $249 CAD or more. The paid upgrade is offered where available.
Delivery details
For delivery in Canada: Standard is $25 CAD below $149 CAD. Priority is $30 CAD below $249 CAD and free from $249 CAD on eligible orders. Adding an item excluded from free Priority removes free Priority for the entire order.
This selected item excludes the entire order from free Priority shipping in Canada. Standard is $25 CAD below $149 CAD and free from $149 CAD. A paid Priority upgrade is $30 CAD where available, including orders of $249 CAD or more.
Thresholds apply after discounts, before taxes and shipping. Product, ground-shipping and destination restrictions may apply. Available services and final charges appear at checkout.
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Selected with care.
NeoGenesis
Skin Serum
Your ritual begins with the right choice.
$206.57 CAD
Taxes calculated at checkout.
The skincare focus
NeoGenesis Skin Serum
NeoGenesis Skin Serum is an advanced, all-in-one daily serum powered by patented S²RM® technology to deliver vital nutrients that support skin health, hydration, and resilience.
Explore our ingredient glossaryNeoGenesis
The formula, explained.
The ingredients behind this formula—and what they bring to your skin.
Squalane
An emollient that helps soften skin and leave it feeling supple.
Glycerin
A humectant that helps attract moisture and keep skin feeling hydrated.
Propanediol
A humectant and solvent that helps distribute ingredients and maintain a comfortable skin feel.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Pairs beautifully.
Explore another step in your face-care routine.
Your routine
NeoGenesisCleanser
Why it fits
NeoGenesis Cleanser is a gentle gel-based formula designed to cleanse and refresh the skin without disrupting its natural pH.
Worth knowing
The finer details.
A closer look at your skin, your routine and what goes into the formula.
NeoGenesis Skin Serum
Regenerative Support | 20% S²RM®
NeoGenesis Skin Serum is an advanced, all-in-one daily serum powered by patented S²RM® technology to deliver vital nutrients that support skin health, hydration, and resilience. This lightweight formula helps improve the look of tone, texture, and overall skin balance, while reinforcing the skin’s natural barrier. Ideal for all skin types, it reduces signs of environmental stressors and promotes a healthier, smoother complexion. For enhanced protection and hydration, layer over NeoGenesis Recovery.
Benefits
- Multi-functional serum suitable for all skin types
- Enhances hydration, tone, and texture
- Supports skin resilience against environmental damage
- Works well alone or layered with other NeoGenesis serums
How to use
- After cleansing, apply to the face, neck, and décolletage. Gently massage into the skin morning and/or evening. For additional hydration and protection, use after NeoGenesis Recovery. Avoid direct eye contact. For external use only.
Full Ingredient List
Water, Human Adipose Mesenchymal Stem Cell Conditioned Media, Human Fibroblast Conditioned Media, Glycerin, Propanediol, Hydroxyethylcellulose, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Squalane, Benzyl Alcohol, Dehydroacetic Acid, Citrus Paradisi (Grapefruit) Peel Oil, Lactic Acid.
Shipping & returns
For delivery and return information, view our policy.
Regenerative Support | 20% S²RM®
NeoGenesis Skin Serum is an advanced, all-in-one daily serum powered by patented S²RM® technology to deliver vital nutrients that support skin health, hydration, and resilience. This lightweight formula helps improve the look of tone, texture, and overall skin balance, while reinforcing the skin’s natural barrier. Ideal for all skin types, it reduces signs of environmental stressors and promotes a healthier, smoother complexion. For enhanced protection and hydration, layer over NeoGenesis Recovery.
Benefits:
- Multi-functional serum suitable for all skin types
- Enhances hydration, tone, and texture
- Supports skin resilience against environmental damage
- Works well alone or layered with other NeoGenesis serums
Loshen’s Recommendation:
For optimal skin nourishment and resilience, apply NeoGenesis Skin Serum after cleansing, followed by your favorite moisturizer. If your skin needs additional barrier support, layer it over NeoGenesis Recovery to lock in hydration and reinforce skin balance.
How to Use:
After cleansing, apply to the face, neck, and décolletage. Gently massage into the skin morning and/or evening. For additional hydration and protection, use after NeoGenesis Recovery. Avoid direct eye contact. For external use only.
Ingredients:
Water, Human Adipose Mesenchymal Stem Cell Conditioned Media, Human Fibroblast Conditioned Media, Glycerin, Propanediol, Hydroxyethylcellulose, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Squalane, Benzyl Alcohol, Dehydroacetic Acid, Citrus Paradisi (Grapefruit) Peel Oil, Lactic Acid.
The care behind your order
From our boutique.
To your door.
A few helpful details, before your next delivery.
Track your orderDelivery
A good thing, on its way.
Delivery details
For delivery in Canada: Standard is $25 CAD below $149 CAD. Priority is $30 CAD below $249 CAD and free from $249 CAD on eligible orders. Adding an item excluded from free Priority removes free Priority for the entire order.
This selected item excludes the entire order from free Priority shipping in Canada. Standard is $25 CAD below $149 CAD and free from $149 CAD. A paid Priority upgrade is $30 CAD where available, including orders of $249 CAD or more.
Thresholds apply after discounts, before taxes and shipping. Product, ground-shipping and destination restrictions may apply. Available services and final charges appear at checkout.
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Collect in Edmonton.
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Here after checkout, too.
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Squalane
An emollient that helps soften skin and leave it feeling supple.
Glycerin
A humectant that helps attract moisture and keep skin feeling hydrated.
Propanediol
A humectant and solvent that helps distribute ingredients and maintain a comfortable skin feel.
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Your skin.
Our attention.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.Personal guidance, in Edmonton or online.
The care behind your care
A place in your routine.
A team in your corner.
From your first question to your next replenishment, there’s a real person here to help.
01 Make sense of what you already use
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our team02 Get to know your skin
Take our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting point03 Keep the conversation going
A question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Explore NeoGenesis.
Find your place to begin.
Discover NeoGenesis Skin Serum at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the NeoGenesis collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
Your ritual, beautifully noted.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.
