



Patchs Defatigants
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15-MINUTE ANTI-FATIGUE EYE PATCHES
Some mornings, your eyes tell the entire story before you've had a chance to.
Biologique Recherche Patchs Défatigants are single-use biocellulose eye patches designed to visibly refresh tired-looking eyes in just 15 minutes.
Their serum is concentrated with ingredients selected to target several common eye-contour concerns at once: puffiness, dark circles, fine dehydration lines and visible wrinkles.
The unique curved “pinch” shape follows the eye contour closely, helping keep the treatment in contact with the delicate skin above and below the eyes.
After use, the eye area appears smoother, fresher and more rested, while puffiness and fine lines look less noticeable.
This is our “I need to look like I slept” treatment.
Skin Instant:
Recommended for tired Skin Instants with under-eye puffiness.
We particularly think about Patchs Défatigants when the eye contour is experiencing:
- Visible puffiness
- Tired-looking eyes
- Fine dehydration lines
- Under-eye wrinkles
- Dark circles
- Morning swelling
- Reduced firmness around the eye contour
- A need for an immediate pre-event refresh
Why the Eye Contour Shows Fatigue So Quickly
The eye contour is one of the first places fatigue becomes visible.
The skin in this area is extremely delicate, and changes in circulation, fluid movement, hydration and skin structure can all affect the way the eyes look.
You may notice:
- Puffiness after waking
- Darker shadows beneath the eyes
- Fine lines appearing more noticeable when the skin is dehydrated
- A heavier or less rested-looking eye contour
And because several of these concerns can happen at the same time, one eye product often needs to do more than simply moisturize.
Patchs Défatigants are designed as a multi-concern eye treatment, targeting puffiness, dark circles, wrinkles and dehydration lines within the same 15-minute ritual.
Why Biocellulose?
These are not traditional fabric eye patches.
Patchs Défatigants use a natural biocellulose support that adheres closely to the skin.
That close contact helps the pre-impregnated treatment stay evenly positioned around the eye contour while you wear it.
The flexible material also adapts beautifully to the curves beneath and around the eye, making it more comfortable and precise than a thicker conventional patch.
- Think of the biocellulose as the delivery system.
- The serum does the treatment.
- The patch keeps it exactly where you want it.
How to Use:
- Begin with clean, dry skin.
- Open the sachet completely.
- Each patch is positioned between a blue fleece layer and a white nylon protective layer.
- Remove the blue fleece, then carefully separate the biocellulose patch from the white nylon.
- Apply the patches around the eye contour, positioning the wider section beneath the eye.
- Leave on for 15 minutes.
- Remove and discard the patches.
- Gently press or massage the remaining serum into the skin until absorbed.
Single-use product.
For external use only.
Loshen & Crem’s Recommendation:
Patchs Défatigants are what we reach for when someone tells us:
- “My eyes look exhausted.”
- “I wake up puffy.”
- “My concealer is settling into every little line today.”
- “I barely slept.”
- “I have an event tonight.”
- “My under-eyes look tired even though the rest of my skin looks great.”
This is not the product we reach for when you need a complicated six-month eye strategy.
It is the product we reach for when you need 15 very productive minutes.
We especially love them before makeup or an event because smoother, better-hydrated-looking skin around the eyes can make concealer sit much more beautifully.
Our favourite ritual?
Apply the patches, lie down for fifteen minutes, and don't answer anyone.
Consider it skincare with boundaries. ;)
The Morning-After Eye Ritual
For especially tired-looking eyes:
- Cleanse gently.
- Apply Patchs Défatigants to dry skin.
- Leave on for 15 minutes.
- Remove and press the remaining serum into the eye contour.
- Follow with the Biologique Recherche eye cream appropriate for your Skin Instant.
- Continue with makeup once the skincare has settled.
No rubbing.
No aggressive massage.
No attempting to erase a bad night's sleep through sheer determination.
Patchs Défatigants vs. Liposmose
Both can make the eye contour appear more rested, but their purpose is different.
Choose Patchs Défatigants when you want:
- A 15-minute intensive treatment
- Immediate visible refreshment
- Puffiness + dark circles + fine lines together
- A pre-event or occasional eye treatment
Choose Liposmose when the primary ongoing concern is:
- Persistent under-eye puffiness
- Water-related bags
- Fatty under-eye bags
- Recurrent congestion around the eyes
Think:
- Patchs Défatigants → immediate multi-concern treatment
- Liposmose → ongoing targeted puffiness serum
The two may also complement one another.
Patchs Défatigants vs. Oligo-Protéines Marines
If dark circles are your biggest concern, the type of darkness matters.
Patchs Défatigants provide an immediate treatment for:
- Fatigue
- Dark circles
- Puffiness
- Fine lines
Oligo-Protéines Marines is a targeted daily serum particularly interesting for:
- Bluish-looking dark circles
- Visible fatigue
- Dullness
- Reduced luminosity
Think:
- Patchs Défatigants → occasional 15-minute eye reset
- Oligo-Protéines Marines → ongoing dark-circle + fatigue serum
Can I Refrigerate Patchs Défatigants?
Biologique Recherche does not currently require refrigeration as part of the official protocol.
That said, some clients enjoy storing the sealed sachet in the refrigerator before use for an additional cooling sensation.
If you choose to do this, the patches should feel pleasantly cool — not painfully cold.
Cooling can make the ritual feel especially refreshing when morning puffiness is part of the concern.
Ingredients:
- Caffeine: Helps support the appearance of a fresher, less puffy eye contour.
- Dipeptide-2: A peptide incorporated into the formula's targeted anti-puffiness complex.
- Albizia Julibrissin Bark Extract: Silk tree extract included within the anti-fatigue and smoothing formulation.
- Hydrolyzed Manihot Esculenta Tuber Extract: Cassava-derived ingredient incorporated into the smoothing complex.
- Sodium Hyaluronate: Helps attract moisture and support a smoother appearance of dehydration lines.
- Hesperidin Methyl Chalcone: A flavonoid-derived ingredient included within the anti-dark-circle complex.
- Palmitoyl Tetrapeptide-7 & Palmitoyl Tripeptide-1: Peptides incorporated into the eye-contour treatment complex.
- N-Hydroxysuccinimide & Chrysin: Ingredients included within the formula's dark-circle-focused complex.
- Biosaccharide Gum-1: Helps support hydration and skin comfort.
Full INCI List:
Water (Aqua), Glycerin, Pentylene Glycol, Albizia Julibrissin Bark Extract, Phenoxyethanol, Polyacrylate-13, Caffeine, Ethylhexylglycerin, Hydrolyzed Manihot Esculenta Tuber Extract, Triethanolamine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Hyaluronate, Polyisobutene, Steareth-20, Disodium EDTA, Hesperidin Methyl Chalcone, Biosaccharide Gum-1, Polysorbate 20, Sorbitan Isostearate, Sodium Citrate, Biotin, Chlorhexidine Digluconate, Chrysin, Citric Acid, Darutoside, Dipeptide-2, N-Hydroxysuccinimide, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Potassium Sorbate, Sodium Benzoate.
The lists of ingredients used in Biologique Recherche products are updated regularly. Before using a Biologique Recherche product, please refer to the ingredient list on its packaging.
If you have allergies or known ingredient sensitivities, please contact us at info@loshen.ca before purchasing. Our team will be happy to help verify the most current ingredient list for you.
Questions We Get About Patchs Défatigants
What are Biologique Recherche Patchs Défatigants?
Patchs Défatigants are single-use biocellulose eye-contour patches designed to visibly reduce signs of fatigue.
Biologique Recherche specifically positions them for tired Skin Instants with under-eye puffiness, with additional anti-wrinkle, anti-dehydration-line and anti-dark-circle actions.
How long do I leave Patchs Défatigants on?
The current Biologique Recherche instructions specify 15 minutes.
Are Patchs Défatigants reusable?
No.
Biologique Recherche currently describes them as a disposable, single-use product.
How often should I use Patchs Défatigants?
The current manufacturer page does not prescribe the older “once weekly for three weeks” protocol.
They may be used as an occasional intensive eye treatment according to the needs of your Skin Instant.
Do Patchs Défatigants help puffiness?
Yes.
Under-eye puffiness is one of their primary current indications.
Do Patchs Défatigants help dark circles?
Yes.
Biologique Recherche classifies them as anti-dark-circle patches in addition to their anti-wrinkle and anti-dehydration-line actions.
Do Patchs Défatigants help wrinkles?
They help visibly smooth the eye contour and reduce the appearance of fine lines and wrinkles after application.
We think of them as an intensive smoothing treatment rather than a replacement for ongoing wrinkle-focused eye care.
Do they help dehydration lines?
Yes.
The current formula contains Sodium Hyaluronate and other moisturizing ingredients that support a smoother-looking eye contour.
Are Patchs Défatigants good before makeup?
This is one of our favourite ways to use them.
A smoother, better-hydrated eye contour can help concealer apply more evenly and look less dry.
Are they good before an event?
Absolutely.
The 15-minute format makes them especially convenient when you want the eye contour to look fresher and more rested before an event.
Can I refrigerate them?
Refrigeration is not required by Biologique Recherche.
Some clients enjoy using them cool for an additional refreshing sensation.
Should I wash off the serum after removing the patches?
No.
After removing the patches, gently allow the remaining serum to absorb into the skin.
What is the difference between Patchs Défatigants and Liposmose?
Patchs Défatigants are an occasional intensive treatment targeting several visible signs of fatigue at once.
Liposmose is an ongoing targeted serum specifically focused on under-eye puffiness and bags.
What is the difference between Patchs Défatigants and Oligo-Protéines Marines?
Patchs Défatigants are a 15-minute treatment for fatigue, puffiness, dark circles and fine lines.
Oligo-Protéines Marines is an ongoing serum particularly targeted toward bluish dark circles and a tired-looking complexion.
Can sensitive skin use Patchs Défatigants?
The eye contour is naturally delicate, so individual tolerance always matters.
If you have known sensitivities or allergies to any of the ingredients, contact us before use so we can help verify the current formula.
Where can I buy authentic Biologique Recherche Patchs Défatigants?
Biologique Recherche Patchs Défatigants are available from Loshen & Crem online and at our Edmonton, Alberta boutique.
Our skin experts can also help determine whether Patchs Défatigants, Liposmose, Oligo-Protéines Marines or another Biologique Recherche eye treatment best suits your current concerns.
Biologique Recherche Skin Reaction Policy
At Loshen & Crem, we highly recommend completing a consultation with one of our skin experts before introducing a new Biologique Recherche product into your routine.
In the event of a skin reaction, Biologique Recherche may require:
- Clear photos of the reaction
- Photos of the product and lot number
- Proof of an online consultation with one of our skin experts
If you choose to purchase a Biologique Recherche product without a consultation and experience a reaction, we may be unable to provide a refund under the brand's policy.
If you are unsure whether Patchs Défatigants are right for your Skin Instant, our team is always available to help.
Free Express Shipping with orders over $199
Available at our Edmonton Boutique
Ship to Canada only
Pickup available at Loshen & Crem
Usually ready in 24 hours

Patchs Defatigants
Single
Loshen & Crem
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
Returns & Refunds
At Loshen & Crem, we understand that sometimes, even the most carefully chosen product might not be "the one."
- Returns: You have 30 days from delivery to return any unopened and unused products in perfect condition—just as they arrived.
- Refunds: If your return reaches us within 30 days of purchase, you’ll have the choice between a refund or store credit (your preference, naturellement). After 30 days, store credit is your only option. Beyond 40 days, refunds and credits are no longer possible.
Final Sale Items
For transparency, certain items are final sale and not eligible for return or exchange:
- Products on sale
- Products marked “Final markdown” on our online store
- Gift cards
- Promotional kits and deluxe samples
- Limited-edition or seasonal item
Shipping Policy
At Loshen & Crem, we take delivering your skincare treasures très seriously. From Canada to the U.S., we’re here to ensure your beauty cabinet is always well-stocked.
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Free Shipping:
- Canada: Complimentary EXPRESS shipping on orders over $199 CAD (after discounts and before taxes).
- United States: Complimentary EXPRESS shipping on orders over $350 USD.
- During our annual sales, enjoy free EXPEDITED shipping for orders over $250 CAD (or $450 USD).
- For smaller indulgences, shipping is $27.95 CAD within Canada and $35 USD to the U.S.
P.S. We ship to P.O. Boxes via Canada Post—but not during strikes. C’est compliqué.
Processing Time:
We aim to dispatch your order within 2 business days, though peak sales and payment verifications may require a touch more patience.
Please note that if you make any changes with the courier after the dispatch, our carrier will charge a $32 fee. In addition, we will have to withdraw 800 points from your La Crème Points account. We appreciate your understanding.
Our processing time starts from the moment your order is successfully submitted and may take up to 2 business days to dispatch your order. However, please be aware that processing and handling time may be extended during peak sale periods. Before we can ship your order, we may need to hold your order for payment verification and confirm your details with your card issuer.
We will do our very best to minimize delays.
Shipping Rates & Delivery Times
Estimated Delivery Times (Canada):
- British Columbia & Alberta: 1–2 business days
- Manitoba & Saskatchewan: 1–2 business days
- Quebec & Ontario: 1–2 business days
- Atlantic Provinces: 1–3 business days
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United States: Delivery times vary by region:
- Zone 1: Eastern States – 3–4 business days
- Zone 2: Central States – 4–5 business days
- Zone 3: Western States – 5 business days
Remote areas may experience longer shipping times.Please Note: Shipping windows are estimates and not guarantees. Delays may occur due to weather, traffic, or additional verification processes.
Shipping Address Details
For a smooth delivery, please provide all relevant information, including buzzer codes, directional suffixes (North, South, etc.), or special instructions.
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Address Changes: Once your package has left our warehouse, address updates cannot be made. If you need to make changes before dispatch, email us at info@loshen.ca with your order details.
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Carrier Fees: Any changes made with the courier after dispatch will incur a $32 CAD fee, and the Free Express Shipping option will be deducted from your La Crème Points account.
Tracking Your Order
All shipments include tracking information, so you can follow your package from our warehouse to your door. A confirmation email with your tracking number will be sent once your order is dispatched.
Damaged or Lost Packages
- Damaged Parcels: If your order arrives damaged, please contact us at info@loshen.ca with photos and details. We’ll work to resolve the issue promptly.
- Lost or Stolen Packages: If your package is marked "delivered" but hasn’t arrived, please contact the carrier directly to file a claim.
Tips to Avoid Lost or Stolen Packages:
- Opt for a signature upon receipt (required for orders over $350 CAD).
- Have your package delivered to your workplace.
- If you’re not home on the expected delivery date, ask a neighbor to receive your package.
Unclaimed Parcels
If your package is returned to us unclaimed, we’ll issue a refund minus a $29.95 CAD return shipping fee.
Free Samples
We believe every order deserves a little extra care! Expect 1–3 complimentary samples selected by our Skincare Specialists to perfectly complement your order.
Loyalty Rewards: La Crem Points
Earn La Crème Points with every purchase and redeem them for future orders. From time to time, we also offer Free Gifts With Purchase (GWP) for select brands, but these are available only while supplies last.
At Loshen & Crem, we aim to deliver excellence at every step of your skincare journey, with care and a touch of elegance. Questions? Don’t hesitate to reach out—we’re always happy to assist!
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A final gesture of care, a whisper of radiance.
La Touche Finale
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With just a few drops, pressed gently into the skin, your complexion is left silky, luminous, and perfectly sealed.






