Your routine
GlyMed PlusComfort Cream with Aloe Vera
Why it fits
A light yet deeply nourishing moisturizer designed to hydrate, soothe, and protect compromised, reactive, or sensitized skin.
GlyMed Bio Renewal Serum
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Explore La Crem rewardsGlyMed+ Bio Renewal Serum is a powerful, peptide-rich serum designed to accelerate cellular turnover, enhance skin texture, and rejuvenate dull or mature skin.
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Boutique details
Your Edmonton boutique.
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Shipping, on usRegular $149+ · Priority $249+ CAD
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Selected with care.
GlyMed Plus
GlyMed Bio Renewal Serum
Your ritual begins with the right choice.
$145.00 CAD
Taxes calculated at checkout.
The skincare focus
GlyMed Bio Renewal Serum
GlyMed+ Bio Renewal Serum is a powerful, peptide-rich serum designed to accelerate cellular turnover, enhance skin texture, and rejuvenate dull or mature skin.
Explore our ingredient glossaryGlyMed Plus
The formula, explained.
The ingredients behind this formula—and what they bring to your skin.
Hexanoyl Dipeptide-3 Norleucine Acetate
Enhances cell turnover and accelerates the skin’s exfoliation process to improve texture and tone.
Palmitoyl Tripeptide-1
Stimulates collagen, elastin, and hyaluronic acid production to reduce wrinkle volume and improve skin firmness.
Palmitoyl Tetrapeptide-7
Reduces skin inflammation, restores collagen synthesis, and promotes a smoother, firmer complexion.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Pairs beautifully.
Explore another step in your face-care routine.
Your routine
GlyMed PlusGlyMed Mega Cream Cleanser
Why it fits
GlyMed Plus Mega Cream Cleanser is an ultra-gentle cream cleanser that effectively dissolves makeup and oil, providing a deep, yet soothing and hydrating cleanse. It is designed to be both thorough and gentle, ensuring that the skin is left clean, soft, and moisturized.
Worth knowing
The finer details.
A closer look at your skin, your routine and what goes into the formula.
GlyMed Bio Renewal Serum
GlyMed+ Bio Renewal Serum is a powerful, peptide-rich serum designed to accelerate cellular turnover, enhance skin texture, and rejuvenate dull or mature skin. This luxurious gel serum is formulated with a blend of multi-functional peptides that work to stimulate the skin's natural exfoliation process, remove damaged cells, and restore firmness. The result is smoother, hydrated, and more youthful-looking skin with a radiant glow. The serum targets the underlying causes of fine lines, wrinkles, and uneven pigmentation, delivering a vibrant, rejuvenated complexion with regular use.
Benefits
- Enhances Cell Turnover: Speeds up the skin’s natural renewal process to create fresher, smoother skin.
- Re-densifies Skin: Strengthens and re-builds the skin’s structure to improve elasticity and firmness.
- Refines Texture: Gently exfoliates to improve skin texture and minimize the appearance of pores.
- Smooths Fine Lines and Wrinkles: Reduces the appearance of wrinkles for a more youthful complexion.
- Brightens Pigmentation: Helps fade dark spots and even skin tone for a glowing, vibrant appearance.
- Boosts Hydration: Provides deep hydration to leave the skin feeling soft, plump, and moisturized.
How to use
- After cleansing and toning, apply one pump of Bio Renewal Serum to your face, neck, and chest in the evening.
- Gently massage the serum into your skin until fully absorbed.
- Follow with your favorite moisturizer.
- In the morning, always apply SPF after using the serum to protect your skin.
Full Ingredient List
Ingredients (INCI): Water, Acetyl Hexapeptide-8, Glycerin, Polysorbate 20, Pentylene Glycol, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Copper Tripeptide-1, Hexanoyl Dipeptide-3 Norleucine Acetate, Panthenol, Glycine, Sorbitol, Dimethyl Mea, Hydrolyzed Soy Protein, Propanediol, Butylene Glycol, Mucor Miehei Extract, Camellia Sinensis (Green Tea) Leaf Extract, Vitis Vinifera (Grape) Seed Extract, Olea Europaea (Olive) Leaf Extract, Carica Papaya Fruit Extract, Citrus Limon (Lemon) Peel Oil, Moringa Oleifera Seed Oil, Vitis Vinifera (Grape) Seed Oil, Citrus Aurantifolia (Lime) Peel Oil, Tocopherol, Tetrahexyldecyl Ascorbate, Lecithin, Carbomer, Caprylyl Glycol, Hexylene Glycol, Phenoxyethanol, Ethylhexylglycerin, Sodium Hydroxide, Mica, Titanium Dioxide, Blue 1, Yellow 5.
Shipping & returns
For delivery and return information, view our policy.
GlyMed+ Bio Renewal Serum is a powerful, peptide-rich serum designed to accelerate cellular turnover, enhance skin texture, and rejuvenate dull or mature skin. This luxurious gel serum is formulated with a blend of multi-functional peptides that work to stimulate the skin's natural exfoliation process, remove damaged cells, and restore firmness. The result is smoother, hydrated, and more youthful-looking skin with a radiant glow. The serum targets the underlying causes of fine lines, wrinkles, and uneven pigmentation, delivering a vibrant, rejuvenated complexion with regular use.
Benefits:
- Enhances Cell Turnover: Speeds up the skin’s natural renewal process to create fresher, smoother skin.
- Re-densifies Skin: Strengthens and re-builds the skin’s structure to improve elasticity and firmness.
- Refines Texture: Gently exfoliates to improve skin texture and minimize the appearance of pores.
- Smooths Fine Lines and Wrinkles: Reduces the appearance of wrinkles for a more youthful complexion.
- Brightens Pigmentation: Helps fade dark spots and even skin tone for a glowing, vibrant appearance.
- Boosts Hydration: Provides deep hydration to leave the skin feeling soft, plump, and moisturized.
How to Use:
- After cleansing and toning, apply one pump of Bio Renewal Serum to your face, neck, and chest in the evening.
- Gently massage the serum into your skin until fully absorbed.
- Follow with your favorite moisturizer.
- In the morning, always apply SPF after using the serum to protect your skin.
Ingredients:
- Hexanoyl Dipeptide-3 Norleucine Acetate: Enhances cell turnover and accelerates the skin’s exfoliation process to improve texture and tone.
- Palmitoyl Tripeptide-1: Stimulates collagen, elastin, and hyaluronic acid production to reduce wrinkle volume and improve skin firmness.
- Palmitoyl Tetrapeptide-7: Reduces skin inflammation, restores collagen synthesis, and promotes a smoother, firmer complexion.
- Acetyl Hexapeptide-8: Reduces wrinkles caused by facial muscle contractions, smoothing out fine lines.
- Copper Tripeptide-1: A powerful peptide that supports healing, boosts collagen production, and delivers beneficial cellular messages for rejuvenation.
- Green Tea Extract: Calms and soothes the skin while providing antioxidant and anti-inflammatory protection.
- Proprietary Fruit Blend (Cranberry, Papaya, and Pineapple): Active fruit enzymes that offer gentle exfoliation, unclog pores, and brighten the skin.
Ingredients (INCI): Water, Acetyl Hexapeptide-8, Glycerin, Polysorbate 20, Pentylene Glycol, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Copper Tripeptide-1, Hexanoyl Dipeptide-3 Norleucine Acetate, Panthenol, Glycine, Sorbitol, Dimethyl Mea, Hydrolyzed Soy Protein, Propanediol, Butylene Glycol, Mucor Miehei Extract, Camellia Sinensis (Green Tea) Leaf Extract, Vitis Vinifera (Grape) Seed Extract, Olea Europaea (Olive) Leaf Extract, Carica Papaya Fruit Extract, Citrus Limon (Lemon) Peel Oil, Moringa Oleifera Seed Oil, Vitis Vinifera (Grape) Seed Oil, Citrus Aurantifolia (Lime) Peel Oil, Tocopherol, Tetrahexyldecyl Ascorbate, Lecithin, Carbomer, Caprylyl Glycol, Hexylene Glycol, Phenoxyethanol, Ethylhexylglycerin, Sodium Hydroxide, Mica, Titanium Dioxide, Blue 1, Yellow 5.
The care behind your order
From our boutique.
To your door.
A few helpful details, before your next delivery.
Track your order01 · Across Canada
A good thing, on its way.
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Collect in Edmonton.
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Here after checkout, too.
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Hexanoyl Dipeptide-3 Norleucine Acetate
Enhances cell turnover and accelerates the skin’s exfoliation process to improve texture and tone.
Palmitoyl Tripeptide-1
Stimulates collagen, elastin, and hyaluronic acid production to reduce wrinkle volume and improve skin firmness.
Palmitoyl Tetrapeptide-7
Reduces skin inflammation, restores collagen synthesis, and promotes a smoother, firmer complexion.
Acetyl Hexapeptide-8
Reduces wrinkles caused by facial muscle contractions, smoothing out fine lines.
Copper Tripeptide-1
A powerful peptide that supports healing, boosts collagen production, and delivers beneficial cellular messages for rejuvenation.
Green Tea Extract
Calms and soothes the skin while providing antioxidant and anti-inflammatory protection.
Proprietary Fruit Blend (Cranberry, Papaya, and Pineapple)
Active fruit enzymes that offer gentle exfoliation, unclog pores, and brighten the skin.
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Your skin.
Our attention.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.Personal guidance, in Edmonton or online.
The care behind your care
A place in your routine.
A team in your corner.
From your first question to your next replenishment, there’s a real person here to help.
01 Make sense of what you already use
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our team02 Get to know your skin
Take our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting point03 Keep the conversation going
A question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Explore GlyMed Plus.
Find your place to begin.
Discover GlyMed Bio Renewal Serum at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the GlyMed Plus collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
Your ritual, beautifully noted.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.