

Dermaceutic Oxybiome Cleansing Micellar Water
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No-Rinse Micellar Water for Makeup, Impurities, Redness and Blemish-Prone Skin
Dermaceutic Oxybiome is a gentle no-rinse micellar water formulated to remove makeup, impurities and pollution particles while supporting the skin’s natural microbiota.
Its daily cleansing formula combines a 2% microbiota regulator with niacinamide and zinc gluconate. Together, these ingredients help purify the skin, regulate the appearance of excess oil and soothe visible redness without leaving the complexion feeling stripped or uncomfortable.
Suitable for the face and eyes, Oxybiome leaves the skin feeling fresh, soft and clean. Its fragrance-free formula is suitable for all skin types and is especially beneficial for sensitive, combination, oily and blemish-prone skin
Benefits
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Gently removes makeup and daily impurities
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Helps remove pollution particles from the skin’s surface
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Purifies without stripping the skin
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Supports the skin’s natural microbiota
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Helps soothe visible redness and discomfort
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Helps regulate the appearance of excess oil
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Supports clearer and healthier-looking skin
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Helps minimize the appearance of enlarged pores
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Leaves the skin feeling fresh, soft and comfortable
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Suitable for the face and eyes
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No rinsing required
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Fragrance-free
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Vegan
- Suitable for all skin types
Best For
Dermaceutic Oxybiome is especially suitable for:
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Daily morning and evening cleansing
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Sensitive or redness-prone skin
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Oily and combination skin
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Blemish-prone skin
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Visible pores and excess sebum
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Skin exposed to pollution and environmental stressors
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Removing face and eye makeup
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Skin that feels tight after traditional cleansing
- All skin types seeking a gentle no-rinse cleanser
How It Works
Oxybiome uses gentle micelles to attract and remove makeup, excess oil and impurities from the skin’s surface without requiring rinsing.
The 2% microbiota regulator combines marine-derived components that provide nutrients to support the skin’s natural microbial balance.
- Niacinamide helps soothe visible redness, support the moisture barrier and regulate the appearance of excess sebum.
- Zinc gluconate provides purifying and sebum-regulating benefits while helping refine the appearance of enlarged pores.
Together, these ingredients cleanse and purify while maintaining skin comfort and supporting a balanced-looking complexion.
Clinical Results
In an in vivo study of Oxybiome:
- 98% of carbon particles were removed from the skin’s surface, compared with 82% on the control area
In a separate 28-day study evaluating Oxybiome in combination with Activabiome:
- 100% agreed that their skin appeared clear, smooth and free from impurities
- 100% agreed that their skin felt fresh after using Oxybiome
The first study was conducted on 10 volunteers. The combined Oxybiome and Activabiome study was conducted on 23 volunteers. Individual results may vary.
How to Use
- Apply morning and evening to dry skin using a cotton pad.
- Gently sweep over the face, neck and eyes to remove makeup and impurities.
- For eye makeup, place the saturated cotton pad over the closed eyelid. Press and hold gently for several seconds to soften the makeup before wiping without rubbing.
- Repeat with a clean cotton pad when necessary.
- Do not rinse.
- Follow with your serum, moisturizer and sunscreen during the day.
Loshen & Crem’s Recommendation
Dermaceutic Oxybiome is an excellent cleanser for clients whose skin feels sensitive, red or uncomfortable after washing.
The press-and-hold technique is especially important around the eyes. Allow the micellar water time to dissolve makeup rather than repeatedly rubbing the delicate eye contour.
Oxybiome can be used alone for light daily cleansing. When removing heavier makeup or water-resistant sunscreen, it may also be used as the first step of a double-cleansing routine, followed by a gentle rinse-off cleanser.
For blemish-prone skin, pair Oxybiome with Dermaceutic Activabiome in the evening. This combination was used in Dermaceutic’s published 28-day study.
Ingredients
- 2% Microbiota Regulator: A blend of marine-derived components that provides nutrients to help support the skin’s natural microbiota and improve the appearance of redness and imperfections.
- Niacinamide: A form of vitamin B3 that helps soothe visible redness, regulate the appearance of excess sebum and support the moisture barrier.
- Zinc Gluconate: A purifying and sebum-regulating ingredient that helps improve the appearance of blemishes and enlarged pores.
- Chlorella Vulgaris and Laminaria Digitata Extracts: Marine algae extracts that help condition the skin and form part of the microbiota-supporting complex.
- Glycerin: A humectant that attracts moisture to the skin and helps maintain comfort during cleansing.
- Micelles: Gentle cleansing agents that attract makeup, excess oil and impurities so they can be removed without harsh rubbing.
Full Ingredient List
Water (Aqua), Glycerin, Poloxamer 184, Pentylene Glycol, Niacinamide, Zinc Gluconate, Chlorella Vulgaris Extract, Laminaria Digitata Extract, Maris Aqua (Sea Water), Saccharide Isomerate, Tetrasodium Glutamate Diacetate, PPG-26-Buteth-26, Phenethyl Alcohol, PEG-40 Hydrogenated Castor Oil, Chlorphenesin, O-Cymen-5-Ol, Citric Acid, Sodium Benzoate.
Ingredient lists may be updated by the manufacturer. Refer to the product packaging for the most current ingredient information.
Frequently Asked Questions
What is Dermaceutic Oxybiome used for?
Oxybiome is a gentle micellar cleansing water designed to remove makeup, excess oil, pollution particles and daily impurities while supporting the skin’s natural microbiota.
Does Oxybiome need to be rinsed off?
No. Oxybiome is designed as a no-rinse micellar water.
Can Oxybiome remove eye makeup?
Yes. It may be applied to the face and eyes. Press a saturated cotton pad gently over the closed eyelid before wiping to minimize rubbing.
Can Oxybiome remove waterproof makeup?
It may remove some long-wearing makeup, but heavier or water-resistant formulas may require a dedicated makeup remover or a second cleansing step.
Is Oxybiome suitable for acne-prone skin?
Yes. Niacinamide and zinc gluconate help regulate the appearance of excess oil, redness and blemishes. The formula is especially suitable for oily, combination and blemish-prone skin.
Is Oxybiome suitable for sensitive skin?
Yes. Its gentle, fragrance-free formula is suitable for sensitive and redness-prone skin.
Can Oxybiome be used every day?
Yes. It is designed for daily use in the morning and evening.
Can Oxybiome be used as the only cleanser?
Yes, particularly for light morning cleansing or removing minimal makeup. Heavier makeup and water-resistant sunscreen may benefit from an additional gentle cleanser.
What is the difference between Oxybiome and Advanced Cleanser?
Oxybiome is a no-rinse micellar water that supports the skin’s microbiota and is especially suitable for sensitive, red or blemish-prone skin.
Advanced Cleanser is a rinse-off cleansing foam designed to remove makeup, impurities and excess sebum.
What is the difference between Oxybiome and Foamer 15?
Oxybiome is a gentle daily micellar cleanser without exfoliating acids.
Foamer 15 is an intensive glycolic acid cleanser designed to exfoliate and refine skin texture. It should not replace a gentle daily cleanser for all skin types.
Can I use Oxybiome with Activabiome?
Yes. Dermaceutic recommends Oxybiome and Activabiome as a two-step routine for blemish-prone skin. Use Oxybiome to cleanse morning and evening, followed by Activabiome at night.
Is Oxybiome fragrance-free?
Yes. The current formula is fragrance-free.
Is Oxybiome vegan?
Yes. Dermaceutic identifies Oxybiome as vegan and cruelty-free.
Can Oxybiome be used during pregnancy or breastfeeding?
Yes. Dermaceutic states that Oxybiome may be used during pregnancy and breastfeeding.
Available at our Edmonton Boutique
Ship to Canada only
Pickup available at Loshen & Crem
Usually ready in 24 hours

Dermaceutic Oxybiome Cleansing Micellar Water
400 ml
Loshen & Crem
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
Returns & Refunds
At Loshen & Crem, we understand that sometimes, even the most carefully chosen product might not be "the one."
- Returns: You have 30 days from delivery to return any unopened and unused products in perfect condition—just as they arrived.
- Refunds: If your return reaches us within 30 days of purchase, you’ll have the choice between a refund or store credit (your preference, naturellement). After 30 days, store credit is your only option. Beyond 40 days, refunds and credits are no longer possible.
Final Sale Items
For transparency, certain items are final sale and not eligible for return or exchange:
- Products on sale
- Products marked “Final markdown” on our online store
- Gift cards
- Promotional kits and deluxe samples
- Limited-edition or seasonal item
Shipping Policy
At Loshen & Crem, we take delivering your skincare treasures très seriously. From Canada to the U.S., we’re here to ensure your beauty cabinet is always well-stocked.
Canada: Loshen & Crem offers express shipping on all eligible Canadian orders.
- Orders under $249: $27.95 express shipping.
- Orders of $249 or more: $10 express shipping.
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Newsletter subscribers receive complimentary express shipping on orders of $249 or more when using the email address associated with their subscription.
Shipping thresholds are calculated after discounts and before taxes. Any applicable shipping charges will be displayed at checkout.
Newsletter subscription status must be active and recognized by Shopify at the time of checkout. Customers should use the same email address they used to subscribe. Newly submitted subscriptions may require a few minutes to become active.
United States: Complimentary EXPRESS shipping on orders over $350 USD.
- During our annual sales, enjoy free EXPEDITED shipping for orders over $250 CAD (or $450 USD).
- For smaller indulgences, shipping is $27.95 CAD within Canada and $35 USD to the U.S.
P.S. We ship to P.O. Boxes via Canada Post—but not during strikes. C’est compliqué.
Processing Time:
We aim to dispatch your order within 2 business days, though peak sales and payment verifications may require a touch more patience.
Please note that if you make any changes with the courier after the dispatch, our carrier will charge a $32 fee. In addition, we will have to withdraw 800 points from your La Crème Points account. We appreciate your understanding.
Our processing time starts from the moment your order is successfully submitted and may take up to 2 business days to dispatch your order. However, please be aware that processing and handling time may be extended during peak sale periods. Before we can ship your order, we may need to hold your order for payment verification and confirm your details with your card issuer.
We will do our very best to minimize delays.
Shipping Rates & Delivery Times
Estimated Delivery Times (Canada):
- British Columbia & Alberta: 1–2 business days
- Manitoba & Saskatchewan: 1–2 business days
- Quebec & Ontario: 1–2 business days
- Atlantic Provinces: 1–3 business days
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United States: Delivery times vary by region:
- Zone 1: Eastern States – 3–4 business days
- Zone 2: Central States – 4–5 business days
- Zone 3: Western States – 5 business days
Remote areas may experience longer shipping times.Please Note: Shipping windows are estimates and not guarantees. Delays may occur due to weather, traffic, or additional verification processes.
Shipping Address Details
For a smooth delivery, please provide all relevant information, including buzzer codes, directional suffixes (North, South, etc.), or special instructions.
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Address Changes: Once your package has left our warehouse, address updates cannot be made. If you need to make changes before dispatch, email us at info@loshen.ca with your order details.
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Carrier Fees: Any changes made with the courier after dispatch will incur a $32 CAD fee, and the Free Express Shipping option will be deducted from your La Crème Points account.
Tracking Your Order
All shipments include tracking information, so you can follow your package from our warehouse to your door. A confirmation email with your tracking number will be sent once your order is dispatched.
Damaged or Lost Packages
- Damaged Parcels: If your order arrives damaged, please contact us at info@loshen.ca with photos and details. We’ll work to resolve the issue promptly.
- Lost or Stolen Packages: If your package is marked "delivered" but hasn’t arrived, please contact the carrier directly to file a claim.
Tips to Avoid Lost or Stolen Packages:
- Opt for a signature upon receipt (required for orders over $350 CAD).
- Have your package delivered to your workplace.
- If you’re not home on the expected delivery date, ask a neighbor to receive your package.
Unclaimed Parcels
If your package is returned to us unclaimed, we’ll issue a refund minus a $29.95 CAD return shipping fee.
Free Samples
We believe every order deserves a little extra care! Expect 1–3 complimentary samples selected by our Skincare Specialists to perfectly complement your order.
Loyalty Rewards: La Crem Points
Earn La Crème Points with every purchase and redeem them for future orders. From time to time, we also offer Free Gifts With Purchase (GWP) for select brands, but these are available only while supplies last.
At Loshen & Crem, we aim to deliver excellence at every step of your skincare journey, with care and a touch of elegance. Questions? Don’t hesitate to reach out—we’re always happy to assist!
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About Us
Loshen & Cream
Let's be clear, this is not about us. It's about you, it's about your skin health.
We are not your typical online skin care boutique. Although we are a virtual store, all of the experts behind Loshen & Crem are true professionals with an outstanding knowledge of the skin.
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