Your routine
GlyMed PlusComfort Cream with Aloe Vera
Why it fits
A light yet deeply nourishing moisturizer designed to hydrate, soothe and protect dry, reactive or sensitized-feeling skin.
GlyMed Plus Radiant Serum
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Explore La Crem rewardsA lightweight, hydrating exfoliating serum designed to brighten, refine texture and smooth the look of fine lines while being gentle enough for sensitive, redness-prone and blemish-prone skin.
Discover the formula & ingredientsPickup in Edmonton
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Boutique details
Your Edmonton boutique.
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Standard free $149 CAD+ · Priority free $249 CAD+ on eligible orders
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This item excludes the entire order from free Priority, including orders of $249 CAD or more. The paid upgrade is offered where available.
Delivery details
For delivery in Canada: Standard is $25 CAD below $149 CAD. Priority is $30 CAD below $249 CAD and free from $249 CAD on eligible orders. Adding an item excluded from free Priority removes free Priority for the entire order.
This selected item excludes the entire order from free Priority shipping in Canada. Standard is $25 CAD below $149 CAD and free from $149 CAD. A paid Priority upgrade is $30 CAD where available, including orders of $249 CAD or more.
Thresholds apply after discounts, before taxes and shipping. Product, ground-shipping and destination restrictions may apply. Available services and final charges appear at checkout.
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Selected with care.
GlyMed Plus
Radiant Serum
Your ritual begins with the right choice.
$122.00 CAD
Taxes calculated at checkout.
The skincare focus
GlyMed Plus Radiant Serum
A lightweight, hydrating exfoliating serum designed to brighten, refine texture and smooth the look of fine lines while being gentle enough for sensitive, redness-prone and blemish-prone skin.
Explore our ingredient glossaryGlyMed Plus
The formula, explained.
The ingredients behind this formula—and what they bring to your skin.
Mandelic Acid (1%)
A gentle alpha-hydroxy acid (AHA) that exfoliates, brightens, and refines texture while minimizing irritation.
Palmitoyl Tripeptide-38 & Palmitoyl Tripeptide-5
Powerful peptides that help firm the look of skin and reduce the look of fine lines.
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine
A skin-strengthening peptide that enhances elasticity and supports long-term firmness.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Pairs beautifully.
Explore another step in your face-care routine.
Your routine
GlyMed PlusMega Cream Cleanser
Why it fits
GlyMed Plus Mega Cream Cleanser is an ultra-gentle cream cleanser that effectively dissolves makeup and oil, providing a deep, yet soothing and hydrating cleanse. It is designed to be both thorough and gentle, ensuring that the skin is left clean, soft, and moisturized.
Worth knowing
The finer details.
A closer look at your skin, your routine and what goes into the formula.
GlyMed Plus Radiant Serum
A lightweight, hydrating exfoliating serum designed to brighten, refine texture and smooth the look of fine lines while being gentle enough for sensitive, redness-prone and blemish-prone skin. Formulated with 1% mandelic acid, this serum gently exfoliates, reduces the look of dark spots and evens skin tone without irritation. A powerhouse peptide complex helps skin look firmer and more elastic, while comfrey and chamomile provide soothing benefits. The result? A radiant, smooth, and even complexion that glows from within.
Benefits
- Gently exfoliates and boosts skin renewal
- Brightens and evens skin tone while reducing hyperpigmentation
- Softens the look of fine lines and wrinkles
- Calms the look of redness, ideal for redness-prone and blemish-prone skin
- Strengthens and firms the skin with advanced peptides
- Pregnancy-safe and suitable for sensitive skin
How to use
- After cleansing and toning, apply 1 pump to face, neck, and chest in the evening.
- Follow with your favorite moisturizer.
- Start 2–3 times per week, gradually increasing to daily use as tolerated.
- Always apply SPF in the morning when using this product.
- ✨ Pro Tip: Perfect for those who want a mild exfoliation without irritation. If your skin is sensitive, redness-prone or blemish-prone, this is your go-to for brighter, smoother skin.
Full Ingredient List
Aqua (Water), Glycerin, Polysorbate 20, Pentylene Glycol, Propanediol, Sodium Hyaluronate, Palmitoyl Tripeptide-38, Palmitoyl Tripeptide-5, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Panthenol, Hydroxypropyl Cyclodextrin, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Mandelic Acid, Camellia Sinensis (Green Tea) Leaf Extract, Symphytum Officinale (Comfrey) Rhizome/Root Extract, Anthemis Nobilis (Chamomile) Flower Extract, Citrus Aurantium Dulcis (Orange) Peel Oil, Citrus Grandis (Grapefruit) Peel Oil, Tocopherol, Xanthan Gum, Carbomer, Phenoxyethanol, Ethylhexylglycerin, Sodium Hydroxide.
Shipping & returns
For delivery and return information, view our policy.
A lightweight, hydrating exfoliating serum designed to brighten, refine texture and smooth the look of fine lines while being gentle enough for sensitive, redness-prone and blemish-prone skin. Formulated with 1% mandelic acid, this serum gently exfoliates, reduces the look of dark spots and evens skin tone without irritation. A powerhouse peptide complex helps skin look firmer and more elastic, while comfrey and chamomile provide soothing benefits. The result? A radiant, smooth, and even complexion that glows from within.
Benefits
- Gently exfoliates and boosts skin renewal
- Brightens and evens skin tone while reducing hyperpigmentation
- Softens the look of fine lines and wrinkles
- Calms the look of redness, ideal for redness-prone and blemish-prone skin
- Strengthens and firms the skin with advanced peptides
- Pregnancy-safe and suitable for sensitive skin
Loshen’s Recommendation
If you’re looking for a gentle exfoliating serum that brightens and smooths without irritation, this is the one. Perfect for redness-prone or sensitive skin, or anyone who wants a mild exfoliant to gradually reveal radiant, even-toned skin. Pair it with hydrating serums or calming moisturizers for ultimate skin balance and glow.
How to Use
- After cleansing and toning, apply 1 pump to face, neck, and chest in the evening.
- Follow with your favorite moisturizer.
- Start 2–3 times per week, gradually increasing to daily use as tolerated.
- Always apply SPF in the morning when using this product.
✨ Pro Tip: Perfect for those who want a mild exfoliation without irritation. If your skin is sensitive, redness-prone or blemish-prone, this is your go-to for brighter, smoother skin.
Ingredients
- Mandelic Acid (1%) – A gentle alpha-hydroxy acid (AHA) that exfoliates, brightens, and refines texture while minimizing irritation.
- Palmitoyl Tripeptide-38 & Palmitoyl Tripeptide-5 – Powerful peptides that help firm the look of skin and reduce the look of fine lines.
- Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine – A skin-strengthening peptide that enhances elasticity and supports long-term firmness.
- Comfrey Extract – A soothing botanical that calms the look of redness and comforts dry skin.
- Chamomile Extract – A calming ingredient that soothes the feeling of irritation.
- Green Tea Extract – A potent antioxidant that fights free radicals and helps protect against environmental damage.
Full Ingredients List
Aqua (Water), Glycerin, Polysorbate 20, Pentylene Glycol, Propanediol, Sodium Hyaluronate, Palmitoyl Tripeptide-38, Palmitoyl Tripeptide-5, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Panthenol, Hydroxypropyl Cyclodextrin, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Mandelic Acid, Camellia Sinensis (Green Tea) Leaf Extract, Symphytum Officinale (Comfrey) Rhizome/Root Extract, Anthemis Nobilis (Chamomile) Flower Extract, Citrus Aurantium Dulcis (Orange) Peel Oil, Citrus Grandis (Grapefruit) Peel Oil, Tocopherol, Xanthan Gum, Carbomer, Phenoxyethanol, Ethylhexylglycerin, Sodium Hydroxide.
The care behind your order
From our boutique.
To your door.
A few helpful details, before your next delivery.
Track your orderDelivery
A good thing, on its way.
Delivery details
For delivery in Canada: Standard is $25 CAD below $149 CAD. Priority is $30 CAD below $249 CAD and free from $249 CAD on eligible orders. Adding an item excluded from free Priority removes free Priority for the entire order.
This selected item excludes the entire order from free Priority shipping in Canada. Standard is $25 CAD below $149 CAD and free from $149 CAD. A paid Priority upgrade is $30 CAD where available, including orders of $249 CAD or more.
Thresholds apply after discounts, before taxes and shipping. Product, ground-shipping and destination restrictions may apply. Available services and final charges appear at checkout.
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Collect in Edmonton.
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Here after checkout, too.
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Mandelic Acid (1%)
A gentle alpha-hydroxy acid (AHA) that exfoliates, brightens, and refines texture while minimizing irritation.
Palmitoyl Tripeptide-38 & Palmitoyl Tripeptide-5
Powerful peptides that help firm the look of skin and reduce the look of fine lines.
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine
A skin-strengthening peptide that enhances elasticity and supports long-term firmness.
Comfrey Extract
A soothing botanical that calms the look of redness and comforts dry skin.
Chamomile Extract
A calming ingredient that soothes the feeling of irritation.
Green Tea Extract
A potent antioxidant that fights free radicals and helps protect against environmental damage.
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Your skin.
Our attention.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.Personal guidance, in Edmonton or online.
The care behind your care
A place in your routine.
A team in your corner.
From your first question to your next replenishment, there’s a real person here to help.
01 Make sense of what you already use
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our team02 Get to know your skin
Take our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting point03 Keep the conversation going
A question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Explore GlyMed Plus.
Find your place to begin.
Discover GlyMed Plus Radiant Serum at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the GlyMed Plus collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
Your ritual, beautifully noted.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.