Your routine
Biologique RechercheLotion P50T
Why it fits
Biologique Recherche’s exfoliating, purifying and balancing lotion for seborrheic Skin Instants. The first step after cleansing.

Skincare Boutique & Facial Institute
Skincare Boutique & Facial Institute
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Explore La Crem rewardsFirst visible signs of aging
A targeted serum focused on the visible effects of glycation, for skin beginning to show the first visible signs of aging. It helps preserve the look of firmness and suppleness while bringing radiance to a tired-looking complexion.
Discover the formula & ingredientsPickup in Edmonton
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5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Biologique Recherche
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The skincare focus
A targeted serum focused on the visible effects of glycation, for skin beginning to show the first visible signs of aging. It helps preserve the look of firmness and suppleness while bringing radiance to a tired-looking complexion.
Explore our ingredient glossaryBiologique Recherche
The ingredients behind this formula—and what they bring to your skin.
Albizia Julibrissin (silk tree) Bark Extract
An anti-glycation botanical that helps protect the skin's structural proteins.
Decarboxy Carnosine HCl (carcinine)
An antioxidant that helps shield the skin from the visible effects of glycation.
Papaver Rhoeas (poppy) Flower Extract
Soothes and comforts the skin.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Cleanse with the milk selected for your Skin Instant, then apply the Lotion P50 selected for your Skin Instant. Apply Sérum A-Glyca, follow with the cream suited to your Skin Instant, and finish with sunscreen in the morning.
Your routine
Biologique Recherche’s exfoliating, purifying and balancing lotion for seborrheic Skin Instants. The first step after cleansing.
Your routine
The cream step for skin showing the first visible signs of aging, applied after Lotion P50 and your serums to smooth and comfort the skin.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
Biologique Recherche Sérum A-Glyca is a targeted anti-glycation serum designed for skin beginning to show the first visible signs of aging.
Its formula focuses specifically on glycation, a process in which excess glucose can bind to the skin's structural proteins, including collagen and elastin. Over time, this can affect their flexibility and contribute to wrinkles, reduced suppleness and visible changes in skin quality.
Sérum A-Glyca helps protect the skin against the visible effects of glycation while supporting a smoother, more supple and radiant-looking complexion. It is particularly interesting for anyone who wants a more preventive approach to preserving skin quality as the first signs of aging appear.
We like Sérum A-Glyca for clients who are just starting to notice the first visible signs of aging and want to be proactive rather than wait. Its focus is very specific: glycation, which most routines never address directly. Its ingredient list is short and focused, and it slips easily into an existing Biologique Recherche routine between the Lotion P50 and the cream. It is a thoughtful, preventive step rather than a heavy corrective one.
First visible signs of aging
Use upward strokes when you apply it, and take it all the way down the neck and décolleté, not just the face.
Water (Aqua), Albizia Julibrissin Bark Extract, Glycerin, Propylene Glycol, Phenoxyethanol, Decarboxy Carnosine HCl, Papaver Rhoeas Flower Extract, Butylene Glycol, Ethylhexylglycerin, Sodium Benzoate.
A process in which excess glucose can bind to the skin's structural proteins, such as collagen and elastin. Over time it can contribute to wrinkles, reduced suppleness and visible changes in skin quality.
It is recommended for Skin Instants showing the first visible signs of aging, and for anyone who wants a more preventive approach.
On clean skin, after your Lotion P50, morning and evening, before the cream suited to your Skin Instant.
A few drops over the face, neck and décolleté, using light upward movements until fully absorbed.
Albizia julibrissin (silk tree) bark extract, decarboxy carnosine HCl (carcinine) and Papaver rhoeas (poppy) flower extract.
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
For delivery and return information, view our policy.
Biologique Recherche Sérum A-Glyca is a targeted anti-glycation serum designed for skin beginning to show the first visible signs of aging.
Its formula focuses specifically on glycation, a process in which excess glucose can bind to the skin's structural proteins, including collagen and elastin. Over time, this can affect their flexibility and contribute to wrinkles, reduced suppleness and visible changes in skin quality.
Sérum A-Glyca helps protect the skin against the visible effects of glycation while supporting a smoother, more supple and radiant-looking complexion. It is particularly interesting for anyone who wants a more preventive approach to preserving skin quality as the first signs of aging appear.
Water (Aqua), Albizia Julibrissin Bark Extract, Glycerin, Propylene Glycol, Phenoxyethanol, Decarboxy Carnosine HCl, Papaver Rhoeas Flower Extract, Butylene Glycol, Ethylhexylglycerin, Sodium Benzoate.
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · A little reassurance
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
An anti-glycation botanical that helps protect the skin's structural proteins.
An antioxidant that helps shield the skin from the visible effects of glycation.
Soothes and comforts the skin.
Curious about your ingredients?
Explore La Matière
A little guidance. A more considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Biologique Recherche Sérum A-Glyca at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Biologique Recherche collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
A little care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. A little reminder, with your team still in reach.