Your routine
Biologique RechercheLiposmose
Why it fits
When puffiness keeps coming back, Liposmose offers ongoing targeted care for the look of under-eye bags, while Patchs Défatigants give an occasional 15-minute refresh.

Skincare Boutique & Facial Institute
Skincare Boutique & Facial Institute
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Explore La Crem rewardsTired eyes with under-eye puffiness
Single-use biocellulose eye patches that visibly refresh tired-looking eyes in 15 minutes. Recommended for tired Skin Instants with under-eye puffiness.
Discover the formula & ingredientsPickup in Edmonton
Usually ready in 24 hours
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Selected with care.
Biologique Recherche
Your ritual begins with the right choice.
$31.00 CAD
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The skincare focus
Single-use biocellulose eye patches that visibly refresh tired-looking eyes in 15 minutes. Recommended for tired Skin Instants with under-eye puffiness.
Explore our ingredient glossaryBiologique Recherche
The ingredients behind this formula—and what they bring to your skin.
Caffeine
Helps support the appearance of a fresher, less puffy eye contour.
Dipeptide-2
A peptide incorporated into the formula's targeted anti-puffiness complex.
Sodium Hyaluronate
Helps attract moisture and support a smoother appearance of dehydration lines.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Cleanse gently, apply the patches to dry skin for 15 minutes, then press the remaining serum into the eye contour. Follow with the eye cream appropriate for your Skin Instant and continue with makeup once the skincare has settled. For ongoing puffiness, Liposmose can complement the patches.
Your routine
When puffiness keeps coming back, Liposmose offers ongoing targeted care for the look of under-eye bags, while Patchs Défatigants give an occasional 15-minute refresh.
Your routine
The eye-contour step of your morning routine, targeting the look of dark circles, puffiness and fine lines around the eyes.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
Biologique Recherche Patchs Défatigants are single-use biocellulose eye patches designed to visibly refresh tired-looking eyes in just 15 minutes.
Their serum is concentrated with ingredients selected to address several common eye-contour concerns at once: the look of puffiness, dark circles, fine dehydration lines and visible wrinkles. After use, the eye area appears smoother, fresher and more rested, while puffiness and fine lines look less noticeable.
The unique curved "pinch" shape follows the eye contour closely. Unlike traditional fabric patches, the natural biocellulose support adheres closely to the skin, helping the pre-impregnated serum stay evenly positioned around the eyes, and its flexible material adapts to the curves beneath and around the eye for a comfortable, precise fit.
This is our "I need to look like I slept" ritual. It is not the product for a complicated six-month eye strategy; it is the one we reach for when you need 15 very productive minutes. We especially love it before makeup or an event, because a smoother, better-hydrated-looking eye contour helps concealer sit much more beautifully. Our favourite ritual: apply the patches, lie down for fifteen minutes and don't answer anyone.
Tired eyes with under-eye puffiness
Apply the patches, lie down for fifteen minutes and don't answer anyone: skincare with boundaries.
Water (Aqua), Glycerin, Pentylene Glycol, Albizia Julibrissin Bark Extract, Phenoxyethanol, Polyacrylate-13, Caffeine, Ethylhexylglycerin, Hydrolyzed Manihot Esculenta Tuber Extract, Triethanolamine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Hyaluronate, Polyisobutene, Steareth-20, Disodium EDTA, Hesperidin Methyl Chalcone, Biosaccharide Gum-1, Polysorbate 20, Sorbitan Isostearate, Sodium Citrate, Biotin, Chlorhexidine Digluconate, Chrysin, Citric Acid, Darutoside, Dipeptide-2, N-Hydroxysuccinimide, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Potassium Sorbate, Sodium Benzoate.
15 minutes, as the current Biologique Recherche instructions specify.
No. They are a single-use product.
Biologique Recherche does not specify a fixed frequency. Use them as an occasional intensive eye ritual according to the needs of your Skin Instant; our estheticians can help you decide.
No. After removing the patches, gently press the remaining serum into the skin until absorbed.
Refrigeration is not required, but some clients enjoy storing the sealed sachet in the fridge for a cooling feel. They should feel pleasantly cool, not painfully cold.
Patchs Défatigants are an occasional 15-minute ritual for several signs of fatigue at once. Liposmose is an ongoing serum focused on the look of under-eye puffiness and bags. The two may complement each other.
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
For delivery and return information, view our policy.
Biologique Recherche Patchs Défatigants are single-use biocellulose eye patches designed to visibly refresh tired-looking eyes in just 15 minutes.
Their serum is concentrated with ingredients selected to address several common eye-contour concerns at once: the look of puffiness, dark circles, fine dehydration lines and visible wrinkles. After use, the eye area appears smoother, fresher and more rested, while puffiness and fine lines look less noticeable.
The unique curved "pinch" shape follows the eye contour closely. Unlike traditional fabric patches, the natural biocellulose support adheres closely to the skin, helping the pre-impregnated serum stay evenly positioned around the eyes, and its flexible material adapts to the curves beneath and around the eye for a comfortable, precise fit.
Water (Aqua), Glycerin, Pentylene Glycol, Albizia Julibrissin Bark Extract, Phenoxyethanol, Polyacrylate-13, Caffeine, Ethylhexylglycerin, Hydrolyzed Manihot Esculenta Tuber Extract, Triethanolamine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Hyaluronate, Polyisobutene, Steareth-20, Disodium EDTA, Hesperidin Methyl Chalcone, Biosaccharide Gum-1, Polysorbate 20, Sorbitan Isostearate, Sodium Citrate, Biotin, Chlorhexidine Digluconate, Chrysin, Citric Acid, Darutoside, Dipeptide-2, N-Hydroxysuccinimide, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Potassium Sorbate, Sodium Benzoate.
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · A little reassurance
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Helps support the appearance of a fresher, less puffy eye contour.
A peptide incorporated into the formula's targeted anti-puffiness complex.
Helps attract moisture and support a smoother appearance of dehydration lines.
A flavonoid-derived ingredient included within the formula's dark-circle-focused complex.
Silk tree extract included within the anti-fatigue and smoothing formulation.
Peptides incorporated into the eye-contour complex.
Curious about your ingredients?
Explore La Matière
A little guidance. A more considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Biologique Recherche Patchs Défatigants at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Biologique Recherche collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
A little care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. A little reminder, with your team still in reach.