Your routine
Biologique RechercheLotion P50T
Why it fits
Biologique Recherche’s exfoliating, purifying and balancing lotion for seborrheic Skin Instants. The first step after cleansing.

Skincare Boutique & Facial Institute
Skincare Boutique & Facial Institute
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Explore La Crem rewardsVisible wrinkles with loss of density
A 3D redensifying, plumping serum for Skin Instants showing visible wrinkles and loss of density. It helps skin look smoother, firmer and more densely plumped while visibly reducing the appearance and length of wrinkles.
Discover the formula & ingredientsPickup in Edmonton
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5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Biologique Recherche
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$93.00 CAD
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The skincare focus
A 3D redensifying, plumping serum for Skin Instants showing visible wrinkles and loss of density. It helps skin look smoother, firmer and more densely plumped while visibly reducing the appearance and length of wrinkles.
Explore our ingredient glossaryBiologique Recherche
The ingredients behind this formula—and what they bring to your skin.
Hydrolyzed Soy Flour
A soy-derived ingredient included in the serum's targeted skin-conditioning formula.
Chlorella Vulgaris Extract
A microalgae-derived botanical extract used within the serum's redensifying complex.
Hydrolyzed Collagen
A skin-conditioning ingredient that contributes to the serum's smoothing and plumping properties.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Cleanse, apply the Lotion P50 selected for your Skin Instant, then your lighter, more fluid serums before Collagène Originel. Finish with your moisturizer, and sunscreen in the morning. Depending on your Skin Instant, Sérum Elastine may sometimes be part of the same personalized routine.
Your routine
Biologique Recherche’s exfoliating, purifying and balancing lotion for seborrheic Skin Instants. The first step after cleansing.
Your routine
Elastine focuses on elasticity and wrinkle smoothing while Collagène Originel focuses on density and plumpness, so depending on your Skin Instant both may sometimes share one personalized routine.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
Biologique Recherche Sérum Collagène Originel is an intensive serum for visible wrinkles and plumpness, designed for skin showing established wrinkles, reduced density and a complexion that no longer looks as full or supported as it once did.
Collagen plays an essential role in how firm and dense skin looks, and several collagen types exist within the different layers of the skin. Collagène Originel is designed around this broader understanding of skin structure: rather than thinking only about the surface appearance of a wrinkle, think of it as a structural and plumping serum.
Its formula combines Hydrolyzed Soy Flour, Chlorella Vulgaris Extract and Hydrolyzed Collagen with glycerin, mineral salts and saponins. It helps skin look smoother, firmer and more densely plumped while visibly reducing the appearance and length of wrinkles.
With continued use, the complexion looks more supported, cushioned and refined.
We reach for Collagène Originel when the conversation shifts from fine lines to a visible change in the density of the skin itself. Firmness, wrinkles, elasticity and density are connected, but they are not identical concerns. When clients tell us their skin seems thinner and their wrinkles are becoming more established, this is the more targeted choice. We think of it as a structural and plumping serum rather than simply another firming serum.
Visible wrinkles with loss of density
Press, don't rub: warm the drops between your palms and press them into the face, neck and décolleté.
Water (Aqua), Glycerin, Methylpropanediol, Caprylyl Glycol, Xanthan Gum, Hydrolyzed Soy Flour, Chlorella Vulgaris Extract, 1,2-Hexanediol, Saponins, Hydrolyzed Collagen, Mineral Salts, Sodium Benzoate.
It refers to improving the appearance of skin that has begun to look thinner, less cushioned or less supported, so it looks fuller, plumper and more resilient.
No. A skincare product does not simply replace the collagen naturally found in the skin. Collagène Originel is formulated to improve how the skin looks rather than to replace your natural collagen.
It may be used when wrinkles are visible, but we particularly like it when lines are becoming more established and come with a loss of density or plumpness. For very early fine lines where elasticity is the greater concern, Sérum Elastine may be the more targeted choice.
VG Tensil focuses on tone, firmness and contour definition. Progeskin takes a broader approach to visible signs of aging. Collagène Originel is more specifically targeted to wrinkles, density and plumpness.
Yes. Biologique Recherche recommends a few drops morning and evening, according to the needs of your Skin Instant.
After cleansing and your Lotion P50. If you use several serums, apply the lighter, more fluid ones first, then Collagène Originel, then your moisturizer.
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
For delivery and return information, view our policy.
Biologique Recherche Sérum Collagène Originel is an intensive serum for visible wrinkles and plumpness, designed for skin showing established wrinkles, reduced density and a complexion that no longer looks as full or supported as it once did.
Collagen plays an essential role in how firm and dense skin looks, and several collagen types exist within the different layers of the skin. Collagène Originel is designed around this broader understanding of skin structure: rather than thinking only about the surface appearance of a wrinkle, think of it as a structural and plumping serum.
Its formula combines Hydrolyzed Soy Flour, Chlorella Vulgaris Extract and Hydrolyzed Collagen with glycerin, mineral salts and saponins. It helps skin look smoother, firmer and more densely plumped while visibly reducing the appearance and length of wrinkles.
With continued use, the complexion looks more supported, cushioned and refined.
Water (Aqua), Glycerin, Methylpropanediol, Caprylyl Glycol, Xanthan Gum, Hydrolyzed Soy Flour, Chlorella Vulgaris Extract, 1,2-Hexanediol, Saponins, Hydrolyzed Collagen, Mineral Salts, Sodium Benzoate.
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · A little reassurance
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
A soy-derived ingredient included in the serum's targeted skin-conditioning formula.
A microalgae-derived botanical extract used within the serum's redensifying complex.
A skin-conditioning ingredient that contributes to the serum's smoothing and plumping properties.
A humectant that attracts water and helps maintain skin hydration.
Included to support overall skin conditioning.
Plant-derived compounds incorporated within the serum's active complex.
Curious about your ingredients?
Explore La Matière
A little guidance. A more considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Biologique Recherche Sérum Collagène Originel at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Biologique Recherche collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
A little care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. A little reminder, with your team still in reach.