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Le MieuxPeptide Foam Cleanser
Why it fits
A nourishing peptide cleanser for soft, supple and comfortably clean skin

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5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Le Mieux
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The skincare focus
A Loshen & Crem bestseller for lasting moisture, barrier support and smoother, firmer-looking skin
Explore our ingredient glossaryLe Mieux
The ingredients behind this formula—and what they bring to your skin.
Hya10+ Complex
Ten forms and derivatives of hyaluronic acid support hydration and visible plumpness.
Galactomyces Ferment Filtrate
Helps condition, hydrate and promote a more luminous-looking complexion.
Palmitoyl Tripeptide-5
Supports the appearance of firmness and elasticity.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Explore another step in your face-care routine.
Your routine
A nourishing peptide cleanser for soft, supple and comfortably clean skin
Your routine
A ceramide and botanical oil serum for dry, depleted and sensitized-looking skin
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
A Loshen & Crem bestseller for lasting moisture, barrier support and smoother, firmer-looking skin
Le Mieux 24 Hr. Age Defying Cream is a rich yet non-greasy moisturizer created for dry, mature and visibly depleted skin. Its multi-dimensional formula combines ten forms of hyaluronic acid with peptides, ceramides, squalane, cupuaçu butter, shea butter and kukui seed oil to replenish moisture and restore a smoother, more resilient appearance.
Designed to provide intense hydration for up to 24 hours, the cream addresses the tightness, roughness and crepey-looking texture that can become more noticeable with age, seasonal dryness or a depleted moisture barrier. It is particularly effective across the neck and décolleté, where the skin often requires more sustained nourishment.
There is a reason this is one of Loshen & Crem’s top-selling moisturizers: it provides the comfort of a genuinely rich cream while maintaining an elegant finish that does not feel excessively heavy or greasy.
Galactomyces Ferment Filtrate, Sodium Hyaluronate, Oryza Sativa (Rice) Bran Water, Hyaluronic Acid, Zinc Hydrolyzed Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Dimethylsilanol, Sodium Hyaluronate Crosspolymer, C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Ascorbyl Propyl Hyaluronate, Palmitoyl Tripeptide-5, Theobroma Grandiflorum Seed Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Squalane, Pyrus Malus (Apple) Fruit Water, Phospholipids, Acetyl Hexapeptide-8, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Acetyl Glutamine, Acetyl Octapeptide-3, DNA, Sodium Carboxymethyl Beta-Glucan, Dipalmitoyl Hydroxyproline, Ceramide EOP, Ceramide NP, Palmitoyl Pentapeptide-4, Vitis Vinifera (Grape) Seed Oil, Butyrospermum Parkii (Shea) Butter, Aleurites Moluccana Seed Oil, Oryza Sativa (Rice) Bran Oil, Enteromorpha Compressa Extract, Morus Alba Root Extract, Saccharomyces Lysate Extract, Tocotrienols, Camellia Sinensis Extract, Vitis Vinifera (Grape) Seed Extract, Vaccinium Myrtillus Seed Extract, Sphingomonas Ferment Extract, Tocopherol, Caprylyl Glycol, Ethylhexylglycerin, Undecylenoyl Glycine, Capryloyl Glycine.
Ingredient lists may change. Always refer to the product packaging for the most current ingredient list, particularly if you have allergies or sensitivities. Contact info@loshen.ca if you need help reviewing the formula before purchasing.
For delivery and return information, view our policy.
A Loshen & Crem bestseller for lasting moisture, barrier support and smoother, firmer-looking skin
Le Mieux 24 Hr. Age Defying Cream is a rich yet non-greasy moisturizer created for dry, mature and visibly depleted skin. Its multi-dimensional formula combines ten forms of hyaluronic acid with peptides, ceramides, squalane, cupuaçu butter, shea butter and kukui seed oil to replenish moisture and restore a smoother, more resilient appearance.
Designed to provide intense hydration for up to 24 hours, the cream addresses the tightness, roughness and crepey-looking texture that can become more noticeable with age, seasonal dryness or a depleted moisture barrier. It is particularly effective across the neck and décolleté, where the skin often requires more sustained nourishment.
There is a reason this is one of Loshen & Crem’s top-selling moisturizers: it provides the comfort of a genuinely rich cream while maintaining an elegant finish that does not feel excessively heavy or greasy.
24 Hr. Age Defying Cream is particularly well suited to:
Combination skin may prefer it as an evening moisturizer or concentrated neck cream. Very oily or congestion-prone skin may find the rich blend of butters and oils more than it needs.
24 Hr. Age Defying Cream combines humectants, barrier lipids, emollients, peptides and antioxidants in one formula. This layered approach allows it to attract moisture while also helping the skin retain it.
The Hya10+ Complex supports surface hydration and visible plumpness. Ceramides, phospholipids and squalane help reinforce the skin’s lipid environment, while cupuaçu and shea butters soften and protect against moisture loss. A multi-peptide complex addresses the appearance of wrinkles, elasticity and firmness.
Use morning and evening after cleansing, toning and applying serum.
Apply a small amount to the face, neck and décolleté. Massage using gentle upward and outward motions until absorbed.
Pay particular attention to areas that feel dry or appear crepey, including the sides of the neck, upper chest and around the jawline. Avoid vigorous rubbing or pulling.
In the morning, finish with broad-spectrum sunscreen. In the evening, use as the final step unless applying a facial oil or another occlusive product.
If the cream feels too rich for the entire face, use a lighter moisturizer through oilier areas and reserve 24 Hr. Age Defying Cream for the cheeks, neck and décolleté.
This is one of our bestselling Le Mieux products because it answers a very common need: skin that requires substantial moisture but does not want to feel coated in a heavy, greasy balm.
It is especially beautiful for mature skin, Edmonton winters, dry climates, travel and periods when the complexion suddenly feels tighter or less resilient. You do not need to wait until skin is considered “mature” to use it—persistent dryness and barrier depletion matter more than age.
Pair it with TGF-β Booster when dehydration, visible firmness and fine lines are the priorities. Apply the serum first, allow it to absorb and seal it in with the cream.
A small amount is generally enough. Applying an excessively thick layer does not guarantee longer hydration and may feel heavy beneath sunscreen or makeup.
The current published ingredient list does not include fragrance or parfum. However, the formula contains multiple botanical extracts, cupuaçu butter, shea butter and kukui seed oil. Sensitive skin and clients with nut allergies should patch test and review the current packaging carefully.
When using retinol or exfoliating acids, apply them according to their directions and follow with 24 Hr. Age Defying Cream. If the skin is persistently burning, peeling or unusually sensitive, pause strong actives rather than expecting moisturizer to compensate for overuse.
Both moisturizers support hydration and visible firmness, but they differ in richness.
If Bio Cell Rejuvenating Cream feels too light by the end of the day, 24 Hr. Age Defying Cream is likely the better choice. If 24 Hr. feels too rich beneath makeup, use Bio Cell Rejuvenating Cream during the day and reserve 24 Hr. for evening.
Le Mieux describes this formula as providing hydration for up to 24 hours. This refers to the cream’s combination of water-binding humectants and moisture-retaining lipids—not a requirement to apply it only once daily.
Hyaluronic acid attracts and holds water at the skin’s surface. Ceramides, phospholipids and squalane support the skin’s lipid environment, while cupuaçu butter, shea butter and kukui seed oil soften the skin and help slow moisture loss.
How long the skin remains comfortable depends on climate, cleansing habits, barrier condition, product amount and individual skin type. Very dry skin may still benefit from morning and evening application.
Hyaluronic acid can help the skin appear plumper and more hydrated, but humectants alone may not be enough for dry or mature skin—particularly in cold, low-humidity climates.
As the skin becomes drier, it may also need emollients and barrier-associated lipids to maintain softness and reduce water loss. This is why 24 Hr. Age Defying Cream pairs its Hya10+ Complex with ceramides, phospholipids, squalane, botanical oils and rich plant butters.
The result is a more complete moisturizing system: humectants attract water, emollients soften rough surface cells and lipids help retain moisture.
Full Ingredient List:
Galactomyces Ferment Filtrate, Sodium Hyaluronate, Oryza Sativa (Rice) Bran Water, Hyaluronic Acid, Zinc Hydrolyzed Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Dimethylsilanol, Sodium Hyaluronate Crosspolymer, C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Ascorbyl Propyl Hyaluronate, Palmitoyl Tripeptide-5, Theobroma Grandiflorum Seed Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Squalane, Pyrus Malus (Apple) Fruit Water, Phospholipids, Acetyl Hexapeptide-8, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Acetyl Glutamine, Acetyl Octapeptide-3, DNA, Sodium Carboxymethyl Beta-Glucan, Dipalmitoyl Hydroxyproline, Ceramide EOP, Ceramide NP, Palmitoyl Pentapeptide-4, Vitis Vinifera (Grape) Seed Oil, Butyrospermum Parkii (Shea) Butter, Aleurites Moluccana Seed Oil, Oryza Sativa (Rice) Bran Oil, Enteromorpha Compressa Extract, Morus Alba Root Extract, Saccharomyces Lysate Extract, Tocotrienols, Camellia Sinensis Extract, Vitis Vinifera (Grape) Seed Extract, Vaccinium Myrtillus Seed Extract, Sphingomonas Ferment Extract, Tocopherol, Caprylyl Glycol, Ethylhexylglycerin, Undecylenoyl Glycine, Capryloyl Glycine.
Ingredient lists may change. Always refer to the product packaging for the most current ingredient list, particularly if you have allergies or sensitivities. Contact info@loshen.ca if you need help reviewing the formula before purchasing.
It provides substantial moisture and barrier support without the excessively heavy finish often associated with rich creams. Clients particularly appreciate it for dryness, mature skin and crepey-looking texture across the neck.
It is best suited to dry, very dry and mature skin. Normal skin may also enjoy it during winter, in dry climates or as an evening moisturizer.
Combination skin may prefer it at night or only on dry areas. Oily or congestion-prone skin may find the blend of butters and oils richer than necessary.
Le Mieux states that the formula provides intense hydration for up to 24 hours. Individual results depend on skin type, climate, cleansing habits and barrier condition. It may still be applied morning and evening.
Yes. The current ingredient list names ten forms and derivatives within the Hya10+ Complex.
That should not be assumed. The different forms vary in molecular structure, skin affinity and film-forming properties, but the finished formula matters more than assigning each one to a particular layer.
Yes. Apply after serum in the morning and evening. Always finish the morning routine with broad-spectrum sunscreen.
Yes. It is particularly well suited to dryness and crepey-looking texture across the neck and upper chest.
No moisturizer can permanently tighten skin or eliminate wrinkles. Hydration can temporarily plump the surface, while peptides, lipids and emollients support a smoother and firmer-looking appearance with consistent use.
Yes. Apply TGF-β Booster first and follow with 24 Hr. Age Defying Cream to seal in hydration.
Yes, provided the skin tolerates the active treatment. Apply the active according to its directions, then follow with the cream. Reduce active-product frequency if persistent irritation develops.
Yes. Apply a thin, even layer and allow it to absorb before sunscreen and makeup. Using too much may feel heavy or contribute to pilling.
No fragrance or parfum is listed in the current published ingredient list. Individual sensitivity to botanical ingredients can still vary.
The formula contains barrier-supporting ingredients, but it is also complex and includes multiple botanical extracts, oils and butters. Sensitive skin should patch test before regular use.
The formula contains shea butter and kukui seed oil. Those with nut allergies should consult their healthcare provider and contact Loshen & Crem for help reviewing the current packaging before use.
The official product page does not identify it as non-comedogenic. Because the formula contains rich butters and oils, congestion-prone skin should introduce it gradually.
They are lab-produced cosmetic peptides commonly used in age-supportive formulas. Their inclusion does not make the cream a medical treatment, and visible results depend on the complete formulation and consistent use.
The current ingredient list includes DNA and does not identify the origin of every ingredient. Vegan status should not be assumed without confirmation from Le Mieux.
The published formula does not list retinoids or exfoliating acids. However, pregnancy and breastfeeding considerations are individual, so consult your physician or qualified healthcare provider before introducing a new product.
No. Apply a separate broad-spectrum sunscreen every morning.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
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Speak with our boutique03 · A little reassurance
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Ten forms and derivatives of hyaluronic acid support hydration and visible plumpness.
Helps condition, hydrate and promote a more luminous-looking complexion.
Supports the appearance of firmness and elasticity.
Helps soften the appearance of expression-related fine lines.
Curious about your ingredients?
Explore La Matière
A little guidance. A more considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Le Mieux 24 Hr. Age Defying Cream at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Le Mieux collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
A little care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. A little reminder, with your team still in reach.