Biophora Bioactive Retinol 60

Biophora Bioactive Retinol 60 is the next step for skin that already tolerates retinol well. It contains 0.5% encapsulated retinol, a higher concentration than Bioactive Retinol 30, released gradually to deliver stronger renewal with less irritation than conventional retinol. It helps address more persistent concerns: stubborn pigmentation and melasma, deeper lines, congestion and breakouts. Squalane and vitamin E keep the skin barrier supported throughout.

Important: Biophora is a professional active brand. A complimentary virtual consultation with one of our estheticians is required before purchasing this product, so we can confirm your skin barrier is healthy and ready for this step.

Benefits:

• 0.5% encapsulated retinol with a gradual release
• Helps fade persistent hyperpigmentation and melasma
• Softens the look of deeper lines and wrinkles
• Helps clear congestion and breakouts for a smoother texture
• Squalane and vitamin E support the skin barrier

How to Use:

• Patch test first: apply a small amount to a discreet area at least 24 hours before your first full application.
• In the evening, apply a small amount to clean, dry skin.
• Start slowly: even if you already use retinol, apply once a week for the first few weeks when stepping up to this strength.
• Increase to every other night for a month, then nightly only if your skin stays comfortable.

Pro tip: Retinol makes the skin more sensitive to the sun. Wear a broad-spectrum SPF every day while using it.

Loshen & Crem’s Recommendation:

• For experienced retinol users with normal to oily skin who have completed the Bioactive Retinol 30 protocol and are ready for the next step.
• The squalane in the formula helps offset the dryness typical of Canadian winters.

Ingredients:

Key Ingredients

• Encapsulated retinol (0.5%): a non-prescription form of vitamin A that releases gradually to support skin renewal while minimizing redness.
• Squalane: hydrates, softens and protects the skin barrier, offsetting the dryness often associated with retinol.
• Vitamin E (tocopherol): an antioxidant that helps soothe and protect the skin from environmental stress.
• Birch bark extract (Betula alba): known for its calming, purifying properties.

Full Ingredients List: Aqua (water), Caprylic capric triglyceride, Mineral oil, Glyceryl Stearate, PEG-100 Stearate, Squalane, Propylene glycol, Dimethicone, Dipropylene glycol, Betula alba bark extract, Scrophularia nodosa extract, Retinol, BHT, Tricaprylin, Polymethyl methacrylate, PEG-40 hydrogenated castor oil, Tocopherol, Phenoxyethanol, Ethylhexylglycerin, Cetyl alcohol, Stearyl alcohol, Carbomer, Disodium EDTA.