Your routine
Biologique RechercheLait VIP O₂
Why it fits
The cleansing step and the first step of your Biologique Recherche routine, removing makeup, sunscreen and impurities before your Lotion P50.
Biologique Recherche Crème VIP O₂
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Explore La Crem rewardsDull, tired-looking skin; city life
A brightening, unifying anti-pollution cream for dull, tired-looking skin. It revives radiance, visibly tightens pores and helps prevent the appearance of the first visible signs of aging.
Discover the formula & ingredientsPickup in Edmonton
Usually ready in 24 hours
Boutique details
Your Edmonton boutique.
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Let’s talk about your skin and what belongs in your routine.
From our boutique to your door
Shipping, on usRegular $149+ · Priority $249+ CAD
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Selected with care.
Biologique Recherche
Crème VIP O₂
Your ritual begins with the right choice.
Taxes calculated at checkout.
The skincare focus
One smart everyday cream for skin that looks tired.
A brightening, unifying anti-pollution cream for dull, tired-looking skin. It revives radiance, visibly tightens pores and helps prevent the appearance of the first visible signs of aging.
Explore our ingredient glossaryBiologique Recherche
The formula, explained.
The ingredients behind this formula—and what they bring to your skin.
Melatonin
Part of the patented VIP O₂ Complex, included to help the skin look more energized and radiant.
Sodium Hyaluronate
Helps attract and hold water for lasting hydration.
Lactobacillus Ferment, Lavandin & Tea Tree
Help purify the look of the skin and bring a soothing feel.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Pairs beautifully.
Cleanse with the milk selected for your Skin Instant, such as Lait VIP O₂, then apply the Lotion P50 selected for your Skin Instant and your Sérums Quintessentiels, such as Fluide VIP O₂. Finish with Crème VIP O₂ and, in the morning, sunscreen. These pairings are suggestions; your routine should be personalized to your Skin Instant.
Your routine
Biologique RechercheLotion P50T
Why it fits
Biologique Recherche’s exfoliating, purifying and balancing lotion for seborrheic Skin Instants. The first step after cleansing.
Worth knowing
The finer details.
A closer look at your skin, your routine and what goes into the formula.
Biologique Recherche Crème VIP O₂
Biologique Recherche Crème VIP O₂ is a brightening and unifying cream that revives radiance and helps prevent the appearance of the first visible signs of aging. Rich in antioxidants, it helps protect the skin from the visible effects of pollution while visibly tightening pores, reducing the appearance of redness and leaving the complexion fresh and luminous.
It is particularly suited to dull, tired-looking skin exposed to pollution or urban stress, and to men or anyone who prefers a simple, all-in-one cream.
The 2025 reformulation keeps its beloved anti-pollution role and adds melatonin to help the skin look more energized and radiant. The upgraded, patented VIP O₂ Complex delivers longer-lasting improvements to hydration, texture and radiance, while lactobacillus ferment, lavandin and tea tree help purify the look of the skin, bring a soothing feel and respect the skin's natural balance.
The new texture is fresher and more fluid, with a non-greasy finish and long-lasting hydration. It can be worn on its own or over serums.
Why we love it
If you loved how the original Crème VIP O₂ brightened your skin and helped protect it from pollution, this new version takes things further. The texture is lighter and fresher and the hydration deeper. We love it for clients who live in a city, travel often or simply want one smart, breathable everyday cream that keeps the skin glowing. It is also an easy recommendation for men who want one simple cream.
Benefits
- Brightens and unifies the complexion
- Helps visibly tighten pores
- Helps protect the skin from pollution and environmental stress
- Soothes and reduces the appearance of redness
- Hydrates the top layers of the epidermis, with long-lasting hydration
- Helps prevent the appearance of the first signs of aging
- Non-greasy texture that can be worn on its own or over serums
Best for
Dull, tired-looking skin; city life
A hazelnut-sized amount is enough: massage it in gently until absorbed, and on busy mornings it can be worn on its own.
How to use
- Apply after the Lotion P50 selected for your Skin Instant and your Sérums Quintessentiels.
- Apply a hazelnut-sized amount of Crème VIP O₂ to the face, neck and décolleté, in the morning and/or evening.
- Massage gently until absorbed.
- Apply broad-spectrum sunscreen every morning.
Full Ingredient List
Water (Aqua), Stearic Acid, Palmitic Acid, Propylene Glycol, Glycerin, Pentylene Glycol, Cetyl Alcohol, Polysorbate 40, Triheptanoin, PEG-2 Stearate, Saccharide Isomerate, Helianthus Annuus (Sunflower) Seed Oil, Taraxacum Officinale (Dandelion) Rhizome/Root Extract, Lavandula Hybrida Extract, Melaleuca Alternifolia (Tea Tree) Leaf Oil, Melatonin, Yeast Extract, Lactobacillus Ferment, Sodium Hyaluronate, Citric Acid, Tocopherol, Phospholipids, 1,2-Hexanediol, Polyacrylate Crosspolymer-6, Triethanolamine, TEA-Stearate, Caprylyl Glycol, p-Anisic Acid, Sodium Benzoate, Sodium Citrate, Phenethyl Alcohol.
Frequently Asked Questions
Who is Crème VIP O₂ for?
Dull, tired-looking skin, visible pores and skin exposed to pollution or city life. It is also a great choice for men or anyone who prefers a simple, all-in-one cream.
What changed with the reformulation?
Melatonin was added, the patented VIP O₂ Complex was upgraded, and lactobacillus ferment, lavandin and tea tree joined the formula. The texture is now fresher and more fluid, with long-lasting hydration.
Can I wear it on its own?
Yes. Its non-greasy texture can be worn on its own or over serums.
Morning or evening?
Apply it in the morning and/or evening, after the Lotion P50 selected for your Skin Instant and your Sérums Quintessentiels. Add sunscreen every morning.
Does it help with pores and redness?
It helps visibly tighten pores and soothes and reduces the appearance of redness.
Consultation & reactions
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
Shipping
For delivery and return information, view our policy.
Biologique Recherche Crème VIP O₂ is a brightening and unifying cream that revives radiance and helps prevent the appearance of the first visible signs of aging. Rich in antioxidants, it helps protect the skin from the visible effects of pollution while visibly tightening pores, reducing the appearance of redness and leaving the complexion fresh and luminous.
It is particularly suited to dull, tired-looking skin exposed to pollution or urban stress, and to men or anyone who prefers a simple, all-in-one cream.
The 2025 reformulation keeps its beloved anti-pollution role and adds melatonin to help the skin look more energized and radiant. The upgraded, patented VIP O₂ Complex delivers longer-lasting improvements to hydration, texture and radiance, while lactobacillus ferment, lavandin and tea tree help purify the look of the skin, bring a soothing feel and respect the skin's natural balance.
The new texture is fresher and more fluid, with a non-greasy finish and long-lasting hydration. It can be worn on its own or over serums.
Benefits
- Brightens and unifies the complexion
- Helps visibly tighten pores
- Helps protect the skin from pollution and environmental stress
- Soothes and reduces the appearance of redness
- Hydrates the top layers of the epidermis, with long-lasting hydration
- Helps prevent the appearance of the first signs of aging
- Non-greasy texture that can be worn on its own or over serums
How to use
- Apply after the Lotion P50 selected for your Skin Instant and your Sérums Quintessentiels.
- Apply a hazelnut-sized amount of Crème VIP O₂ to the face, neck and décolleté, in the morning and/or evening.
- Massage gently until absorbed.
- Apply broad-spectrum sunscreen every morning.
Ingredients
Water (Aqua), Stearic Acid, Palmitic Acid, Propylene Glycol, Glycerin, Pentylene Glycol, Cetyl Alcohol, Polysorbate 40, Triheptanoin, PEG-2 Stearate, Saccharide Isomerate, Helianthus Annuus (Sunflower) Seed Oil, Taraxacum Officinale (Dandelion) Rhizome/Root Extract, Lavandula Hybrida Extract, Melaleuca Alternifolia (Tea Tree) Leaf Oil, Melatonin, Yeast Extract, Lactobacillus Ferment, Sodium Hyaluronate, Citric Acid, Tocopherol, Phospholipids, 1,2-Hexanediol, Polyacrylate Crosspolymer-6, Triethanolamine, TEA-Stearate, Caprylyl Glycol, p-Anisic Acid, Sodium Benzoate, Sodium Citrate, Phenethyl Alcohol.
Skin Reaction Policy
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
The care behind your order
From our boutique.
To your door.
A few helpful details, before your next delivery.
Track your order01 · Across Canada
A good thing, on its way.
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Collect in Edmonton.
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · A little reassurance
Here after checkout, too.
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Melatonin
Part of the patented VIP O₂ Complex, included to help the skin look more energized and radiant.
Sodium Hyaluronate
Helps attract and hold water for lasting hydration.
Lactobacillus Ferment, Lavandin & Tea Tree
Help purify the look of the skin and bring a soothing feel.
Dandelion Root Extract & Yeast Extract
Botanical and biotech ingredients that support a fresh, revitalized-looking complexion.
Tocopherol
An antioxidant that helps protect the skin from environmental stress.
Curious about your ingredients?
Explore La Matière
A little guidance. A more considered routine.
Your skin.
Our attention.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book your consultation Just a product question? Ask us.Personal guidance, in Edmonton or online.
The care behind your care
A place in your routine.
A team in your corner.
From your first question to your next replenishment, there’s a real person here to help.
01 Make sense of what you already use
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our team02 Get to know your skin
Take our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting point03 Keep the conversation going
A question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Explore Biologique Recherche.
Find your place to begin.
Discover Biologique Recherche Crème VIP O₂ at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Biologique Recherche collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
A little care, to keep.
Your ritual, beautifully noted.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. A little reminder, with your team still in reach.