Your routine
Biologique RechercheLotion P50T
Why it fits
Biologique Recherche’s exfoliating, purifying and balancing lotion for seborrheic Skin Instants. The first step after cleansing.

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Explore La Crem rewardsBlemish-prone skin
A purifying cream for blemish-prone skin that helps clear up the look of blemishes, rebalance the skin and even out the complexion. It hydrates without leaving an oily feel.
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Biologique Recherche
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The skincare focus
A purifying cream for blemish-prone skin that helps clear up the look of blemishes, rebalance the skin and even out the complexion. It hydrates without leaving an oily feel.
Explore our ingredient glossaryBiologique Recherche
The ingredients behind this formula—and what they bring to your skin.
Niacinamide (Vitamin B3)
One of the cream's oil-balancing active ingredients, helping balance the look of excess oil and shine.
Oleanolic Acid
Part of the oil-balancing complex that helps control the look of shine.
Meadowsweet Extract
A micro-exfoliant active that helps refine the look of the skin.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Cleanse with the milk selected for your Skin Instant, then apply the Lotion P50 selected for your Skin Instant and your serums, such as Complexe Iribiol. Use Masque Vivant at the frequency your esthetician recommends. If your skin feels tight, add an intensely moisturizing serum before the cream. Finish with sunscreen in the morning. These pairings are suggestions; your routine should be personalized to your Skin Instant.
Your routine
Biologique Recherche’s exfoliating, purifying and balancing lotion for seborrheic Skin Instants. The first step after cleansing.
Your routine
The purifying mask step for skin prone to excess oil and blemishes, applied after cleansing and Lotion P50 and before your serums and cream. It gives oil-prone skin a rebalancing reset rather than daily care.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
Biologique Recherche Crème Dermopurifiante is a purifying cream for blemish-prone skin. It helps clear up the look of blemishes, rebalance the skin and even out the complexion, while reducing the look of redness from blemishes and helping balance the look of excess oil.
It contains twenty concentrated active ingredients for blemish-prone skin, grouped by role: micro-exfoliant actives such as meadowsweet extract, purifying actives including yeast extract, oil-balancing actives such as vitamin B3, astringent actives such as milfoil and horse chestnut extracts, soothing actives including arnica and centella asiatica, and revitalizing, hydrating actives such as lavender extract.
The cream visibly tightens the look of pores, hydrates the skin without leaving an oily sensation and helps protect the skin from external aggressors.
Blemish-prone skin still needs a real cream, and Crème Dermopurifiante shows it does not have to feel heavy or greasy. We love that it works on several fronts at once: the look of blemishes, redness, shine and pores. It is the cream we think of when the skin is oily and congested but still needs hydration. Paired with the Lotion P50 selected for your Skin Instant, Masque Vivant and Complexe Iribiol, it becomes the finishing step of a complete purifying routine.
Blemish-prone skin
If your skin feels tight, don't switch to a richer cream: add an intensely moisturizing serum before Crème Dermopurifiante.
WATER (AQUA), GLYCERIN, PROPYLENE GLYCOL, DICAPRYLYL CARBONATE, BUTYLENE GLYCOL, SUCROSE POLYSTEARATE, C10-18 TRIGLYCERIDES, CETYL ALCOHOL, GLYCERAL STEARATE CITRATE, PENTAERYTHRITYL TETRASTEARATE, 1,2 HEXANDIOL, BORON NITRIDE, NIACINAMIDE, BETULA ALBA BARK EXTRACT, EQUISETUM ARVENSE EXTRACT, HEDERA HELIX (IVY)LEAF/STEM EXTRACT, FUCUS VESICULOSUS EXTRACT, HYDROLYZED ALGIN, CENTELLA ASIATICA EXTRACT, SPIRAREA ULMARIA EXTRACT, ARNICA MONTANA FLOWER EXTRACT, ROSA CANINA FRUIT EXTRACT, MYRTUS COMMUNIS LEAF EXTRACT, ACHILLEA MILLEFOLIUM EXTRACT, AESCULUS HIPPOCASTANUM (HORSE CHESTNUT) SEED EXTRACT, LAVANDULA FLOWER/LEAF/STEM EXTRACT, ALLIUM CEPA (ONION) BULB EXTRACT, COMMIPHORA MYRRHA RESIN EXTRACT, OLEONOLIC ACID, YEAST EXTRACT, CITRIC ACID, TOCOPHEROL, CARAMEL POLYACRYLATE CROSSPOLYMER-6, ZINC SULFATE, CAPRYLYL GLYCOL, SODIUM BENZOATE, POTASSIUM SORBATE.
Blemish-prone skin that needs help with the look of blemishes, redness, excess oil and uneven tone.
No. It hydrates the skin without leaving an oily sensation.
Apply a hazelnut-sized amount to the face after the Lotion P50 selected for your Skin Instant and your Sérums Quintessentiels.
Apply an intensely moisturizing serum before the cream.
It visibly tightens the look of pores and helps balance the look of excess oil.
It pairs well with the Lotion P50 selected for your Skin Instant, Masque Vivant and Complexe Iribiol. These are suggestions; your esthetician will personalize the routine to your Skin Instant.
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
For delivery and return information, view our policy.
Biologique Recherche Crème Dermopurifiante is a purifying cream for blemish-prone skin. It helps clear up the look of blemishes, rebalance the skin and even out the complexion, while reducing the look of redness from blemishes and helping balance the look of excess oil.
It contains twenty concentrated active ingredients for blemish-prone skin, grouped by role: micro-exfoliant actives such as meadowsweet extract, purifying actives including yeast extract, oil-balancing actives such as vitamin B3, astringent actives such as milfoil and horse chestnut extracts, soothing actives including arnica and centella asiatica, and revitalizing, hydrating actives such as lavender extract.
The cream visibly tightens the look of pores, hydrates the skin without leaving an oily sensation and helps protect the skin from external aggressors.
WATER (AQUA), GLYCERIN, PROPYLENE GLYCOL, DICAPRYLYL CARBONATE, BUTYLENE GLYCOL, SUCROSE POLYSTEARATE, C10-18 TRIGLYCERIDES, CETYL ALCOHOL, GLYCERAL STEARATE CITRATE, PENTAERYTHRITYL TETRASTEARATE, 1,2 HEXANDIOL, BORON NITRIDE, NIACINAMIDE, BETULA ALBA BARK EXTRACT, EQUISETUM ARVENSE EXTRACT, HEDERA HELIX (IVY)LEAF/STEM EXTRACT, FUCUS VESICULOSUS EXTRACT, HYDROLYZED ALGIN, CENTELLA ASIATICA EXTRACT, SPIRAREA ULMARIA EXTRACT, ARNICA MONTANA FLOWER EXTRACT, ROSA CANINA FRUIT EXTRACT, MYRTUS COMMUNIS LEAF EXTRACT, ACHILLEA MILLEFOLIUM EXTRACT, AESCULUS HIPPOCASTANUM (HORSE CHESTNUT) SEED EXTRACT, LAVANDULA FLOWER/LEAF/STEM EXTRACT, ALLIUM CEPA (ONION) BULB EXTRACT, COMMIPHORA MYRRHA RESIN EXTRACT, OLEONOLIC ACID, YEAST EXTRACT, CITRIC ACID, TOCOPHEROL, CARAMEL POLYACRYLATE CROSSPOLYMER-6, ZINC SULFATE, CAPRYLYL GLYCOL, SODIUM BENZOATE, POTASSIUM SORBATE.
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
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$249+Free Priority shipping
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Speak with our boutique03 · A little reassurance
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
One of the cream's oil-balancing active ingredients, helping balance the look of excess oil and shine.
Part of the oil-balancing complex that helps control the look of shine.
A micro-exfoliant active that helps refine the look of the skin.
One of the purifying active ingredients that help clarify the look of blemish-prone skin.
Astringent actives that help tighten the look of pores.
Soothing actives that help reduce the look of redness.
Curious about your ingredients?
Explore La Matière
A little guidance. A more considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book your consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Biologique Recherche Crème Dermopurifiante at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Biologique Recherche collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
A little care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. A little reminder, with your team still in reach.