Your routine
Biologique RechercheLotion P50T
Why it fits
Biologique Recherche’s exfoliating, purifying and balancing lotion for seborrheic Skin Instants. The first step after cleansing.

Skincare Boutique & Facial Institute
Skincare Boutique & Facial Institute
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Explore La Crem rewardsMature, dry and reactive skin
A rich moisturizing and lipid-replenishing cream for mature, dry and reactive skin, and skin that reddens easily. It visibly reconditions the skin and brings comfort all day, especially in winter, wind and cold.
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5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Biologique Recherche
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The skincare focus
A rich moisturizing and lipid-replenishing cream for mature, dry and reactive skin, and skin that reddens easily. It visibly reconditions the skin and brings comfort all day, especially in winter, wind and cold.
Explore our ingredient glossaryBiologique Recherche
The ingredients behind this formula—and what they bring to your skin.
Grape Seed Oil
One of the cream's lipid-replenishing ingredients.
Hyaluronic Acid & Sugar Derivatives
Hygroscopic ingredients that help attract and hold water in the skin.
Walnut Extract & Cranberry Seed Oil
Protective ingredients included in the formula.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Cleanse with the milk selected for your Skin Instant, apply the Lotion P50 selected for your Skin Instant, then your mask and serums. For extra lipids, pair it with Sérum T.E.W.L. before the cream. Finish with Crème Dermo-RL and add sunscreen in the morning. These pairings are suggestions; your esthetician will personalize the routine to your Skin Instant.
Your routine
Biologique Recherche’s exfoliating, purifying and balancing lotion for seborrheic Skin Instants. The first step after cleansing.
Your routine
Sérum T.E.W.L. adds extra lipids under Crème Dermo-RL, a natural match for dry, lipid-deprived skin.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
Biologique Recherche Crème Dermo-RL is a moisturizing and hydrating cream that visibly reconditions the skin. It replenishes the skin's lipids, while fatty acids support the skin's natural functions, radiance and vitality.
A complete cream for lipid-deprived and dehydrated skin, its texture is brimming with moisturizing, lipid-replenishing and protective ingredients. It brings a sensation of comfort immediately after application and throughout the day, and the skin regains its radiance and vitality, day after day.
Crème Dermo-RL is designed for mature, dry and reactive skin, skin that reddens easily, and skin exposed to wind and cold. It is excellent in the winter months. It is not for oily skin.
When our clients' skin feels tight, reactive and dry, especially in the depth of winter, Crème Dermo-RL is one of the first creams we think of. It replenishes lipids and brings comfort that lasts throughout the day. We love layering it over Sérum T.E.W.L. for skin that needs even more lipids. It is our go-to cream to face wind and cold.
Mature, dry and reactive skin
In winter, press a few drops of Sérum T.E.W.L. under Crème Dermo-RL for extra lipids against wind and cold.
WATER (AQUA), VITIS VINIFERA (GRAPE) SEED OIL, BUTYROSPERMUM PARKII (SHEA) BUTTER, PROPANEDIOL DICAPRYLATE, C12-16 ALCOHOLS, GOSSYPIUM HERBACEUM (COTTON) SEED OIL, PENTYLENE GLYCOL, PENTAERYTHRITYL TETRASTEARATE, POLYAMIDE-5, VACCINIUM MACROCARPON (CRANBERRY) SEED OIL, XYLITYLGLUCOSIDES, HYDROGENATED LECITHIN, PALMITIC ACID, GLYCERIN, SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL, ANHYDROXYLITOL, SODIUM HYALURONATE, PSEUDOALTEROMONAS FERMENT EXTRACT, XYLITOL, TOCOPHEROL, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, JUGLANS REGIA ( WALNUT) SEED EXTRACT, CANANGA ODORATA FLOWER OIL, CITRUS AURANTIUM AMARA (BITTER ORANGE) FLOWER OIL, OPUNTIA FICUS-INDICA FRUIT EXTRACT,GLYCERYL STEARATE CITRATE, POLYSORBATE 60, SORBITAN ISOSTEARATE, PHENOXYETHANOL, RHIZOBIAN GUM, HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER, CHLORPHENESIN, SALICYLIC ACID, SODIUM METABISULFITE, SODIUM HYDROXIDE, BENZYL BENZOATE, BENZYL SALICYLATE, FARNESOL, GERANIOL, LIMONENE, LINALOOL.
Mature, dry and reactive skin, skin that reddens easily, and skin exposed to wind and cold.
No. Crème Dermo-RL is not for skin with oily tendencies.
It is recommended for daytime use; the directions allow morning and/or evening application. It is excellent in the winter months.
Sérum T.E.W.L., for extra lipids.
After your milk, Lotion P50, mask and serums, apply a small dab to the face, neck and décolleté and massage delicately with your fingertips, using upward and outward strokes until absorbed.
Yes. Its ingredient list includes essential oils (ylang-ylang and bitter orange flower) and aromatic compounds such as linalool, limonene and geraniol. Check the full ingredient list if you are sensitive to fragrance ingredients.
Yes. The formula contains ingredients derived from walnut. If you have a nut allergy, please book a consultation with one of our estheticians before purchasing.
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
For delivery and return information, view our policy.
Biologique Recherche Crème Dermo-RL is a moisturizing and hydrating cream that visibly reconditions the skin. It replenishes the skin's lipids, while fatty acids support the skin's natural functions, radiance and vitality.
A complete cream for lipid-deprived and dehydrated skin, its texture is brimming with moisturizing, lipid-replenishing and protective ingredients. It brings a sensation of comfort immediately after application and throughout the day, and the skin regains its radiance and vitality, day after day.
Crème Dermo-RL is designed for mature, dry and reactive skin, skin that reddens easily, and skin exposed to wind and cold. It is excellent in the winter months. It is not for oily skin.
WATER (AQUA), VITIS VINIFERA (GRAPE) SEED OIL, BUTYROSPERMUM PARKII (SHEA) BUTTER, PROPANEDIOL DICAPRYLATE, C12-16 ALCOHOLS, GOSSYPIUM HERBACEUM (COTTON) SEED OIL, PENTYLENE GLYCOL, PENTAERYTHRITYL TETRASTEARATE, POLYAMIDE-5, VACCINIUM MACROCARPON (CRANBERRY) SEED OIL, XYLITYLGLUCOSIDES, HYDROGENATED LECITHIN, PALMITIC ACID, GLYCERIN, SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL, ANHYDROXYLITOL, SODIUM HYALURONATE, PSEUDOALTEROMONAS FERMENT EXTRACT, XYLITOL, TOCOPHEROL, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, JUGLANS REGIA ( WALNUT) SEED EXTRACT, CANANGA ODORATA FLOWER OIL, CITRUS AURANTIUM AMARA (BITTER ORANGE) FLOWER OIL, OPUNTIA FICUS-INDICA FRUIT EXTRACT,GLYCERYL STEARATE CITRATE, POLYSORBATE 60, SORBITAN ISOSTEARATE, PHENOXYETHANOL, RHIZOBIAN GUM, HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER, CHLORPHENESIN, SALICYLIC ACID, SODIUM METABISULFITE, SODIUM HYDROXIDE, BENZYL BENZOATE, BENZYL SALICYLATE, FARNESOL, GERANIOL, LIMONENE, LINALOOL.
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · A little reassurance
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
One of the cream's lipid-replenishing ingredients.
Hygroscopic ingredients that help attract and hold water in the skin.
Protective ingredients included in the formula.
Help condition and visibly recondition the skin.
Help condition the skin and support its comfort.
Curious about your ingredients?
Explore La Matière
A little guidance. A more considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book your consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Biologique Recherche Crème Dermo-RL at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Biologique Recherche collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
A little care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. A little reminder, with your team still in reach.