Your routine
Biologique RechercheLotion P50T
Why it fits
Each serum in the set is applied after cleansing and the Lotion P50 selected for your Skin Instant, the step that comes just before the serums.

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Explore La Crem rewardsSkin showing visible signs of aging
A limited-edition quartet of Biologique Recherche Quintessential Serums for visible signs of aging, with a La Grande Crème deluxe sample, presented in a Royal Blue travel case.
Discover the formula & ingredientsPickup in Edmonton
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5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Biologique Recherche
Your ritual begins with the right choice.
$499.00 CAD
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The skincare focus
A limited-edition quartet of Biologique Recherche Quintessential Serums for visible signs of aging, with a La Grande Crème deluxe sample, presented in a Royal Blue travel case.
Explore our ingredient glossaryBiologique Recherche
The ingredients behind this formula—and what they bring to your skin.
Tripeptide-2
In Sérum Progeskin. A peptide included to help skin look firmer and smoother.
Hydrolyzed Soy Flour
In Sérum Collagène Originel. A soy-derived ingredient included in the serum's targeted skin-conditioning formula.
Palmitoyl Hexapeptide-12
In Sérum Élastine. A peptide associated with the elastin-focused complex and the serum's smoothing action.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Cleanse, then apply the Lotion P50 selected for your Skin Instant. Apply the serums from the set one at a time or layered, then finish with your preferred Biologique Recherche cream, such as La Grande Crème, and sunscreen in the morning.
Your routine
Each serum in the set is applied after cleansing and the Lotion P50 selected for your Skin Instant, the step that comes just before the serums.
Your routine
The cream step for skin showing visible signs of aging, applied after Lotion P50 and your Quintessential Serums, and before Le Grand Sérum for the full ritual.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
Masters of Time brings together four Biologique Recherche Quintessential Serums, curated to address visible signs of aging: loss of firmness and elasticity, fine lines and dullness. Used together, the formulas work in synergy for a smoother, plumper, more luminous-looking complexion.
The set includes Sérum Progeskin (8 ml), Sérum Collagène Originel (8 ml), Sérum VG Tensil (8 ml), Sérum Elastine (8 ml) and a La Grande Crème deluxe sample (5 ml), presented in the Biologique Recherche Royal Blue Travel Makeup Case with gold detailing.
Use each serum on its own for targeted care, or layer up to four to build a complete routine for visible signs of aging.
This set is perfect for discovering or deepening a Biologique Recherche ritual, whether you are new to the line or a devoted fan. Four Quintessential Serums side by side make it easy to feel how each one fits your skin. We like that it can be used one serum at a time or as a full layered routine. It is a sophisticated investment in how resilient your skin looks in the years ahead.
Skin showing visible signs of aging
Start with Sérum Elastine in the morning and Sérum VG Tensil or Collagène Originel in the evening, then add layers as your esthetician suggests.
Biologique Recherche Sérum Progeskin
WATER (AQUA), PROPYLENE GLYCOL, GLYCERIN, METHYLPROPANEDIOL, ETHOXYDIGLYCOL, CAPRYLYL GLYCOL, CENTAUREA CYANUS FLOWER EXTRACT, XANTHAN GUM, JUGLANS REGIA (WALNUT) SEED EXTRACT, JUGLANS REGIA (WALNUT) SHELL EXTRACT, BENZOIC ACID, DISODIUM EDTA, SODIUM METABISULFITE, SORBIC ACID, TRIPEPTIDE-2.
Biologique Recherche Sérum Collagène Originel
Water (Aqua), Glycerin, Methylpropanediol, Caprylyl Glycol, Xanthan Gum, Hydrolyzed Soy Flour, Chlorella Vulgaris Extract, 1,2-Hexanediol, Saponins, Hydrolyzed Collagen, Mineral Salts, Sodium Benzoate.
Biologique Recherche VG Tensil
Water (Aqua), Hydrolyzed Hazelnut Protein, Pentylene Glycol, Propylene Glycol, Hydrolyzed Manihot Esculenta Tuber Extract, Secale Cereale (Rye) Seed Extract, Juglans Regia (Walnut) Shell Extract, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate, Ethylhexylglycerin.
Biologique Recherche Sérum Élastine
Water (Aqua), Propylene Glycol, Glycerin, Glyceryl Polymethacrylate, Methylpropanediol, Butylene Glycol, Equisetum Arvense Extract, PEG-8, Caprylyl Glycol, Triethanolamine, Alteromonas Ferment Extract, Phenethyl Alcohol, Sodium Hyaluronate, Carbomer, Polysorbate 20, Sodium Lactate, Acacia Senegal Gum, Xanthan Gum, Sodium Hyaluronate Crosspolymer, Farnesol, Palmitoyl Hexapeptide-12, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1.
Biologique Recherche La Grande Crème
WATER (AQUA), OCTYLDODECANOL, CETEARYL ALCOHOL, GLYCERYL STEARATE, BUTYLENE GLYCOL, GLYCERIN, PROPANEDIOL, ALCOHOL DENAT., UNDECANE, BUTYROSPERMUM PARKII (SHEA) BUTTER, PROPYLENE GLYCOL, CETEARETH-20, PENTAERYTHRITYL TETRASTEARATE, SORBITAN STEARATE, CERA ALBA (BEESWAX), CAMELLIA SINENSIS LEAF EXTRACT, PAEONIA ALBIFLORA ROOT EXTRACT, MIMOSA TENUIFLORA BARK EXTRACT, ONOPORDUM ACANTHIUM FLOWER/LEAF/STEM EXTRACT, VITIS VINIFERA (GRAPE) JUICE EXTRACT, JASMINUM GRANDIFLORUM (JASMINE) FLOWER EXTRACT, SAMBUCUS NIGRA FLOWER EXTRACT, TERMINALIA CATAPPA LEAF EXTRACT, SOY ISOFLAVONES, LEPIDIUM SATIVUM SPROUT EXTRACT, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, LACTOBACILLUS/WASABIA JAPONICA ROOT FERMENT EXTRACT, PICHIA ANOMALA EXTRACT, ACETYL HEXAPEPTIDE-8, PALMITOYL OLIGOPEPTIDE, PENTAPEPTIDE-48, PALMITOYL TETRAPEPTIDE-7, ALPHA-GLUCAN OLIGOSACCHARIDE, DECARBOXY CARNOSINE HCL, SODIUM LACTATE, TANNIC ACID, CARUM CARVI (CARAWAY) FRUIT OIL, MENTHA PIPERITA (PEPPERMINT) OIL, CETYL PALMITATE, COCOGLYCERIDES, LECITHIN, HYDROGENATED LECITHIN, MALTODEXTRIN, TOCOPHEROL, CARBOMER, TRIDECANE, POLYSORBATE 80, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, TRIETHANOLAMINE, PVP, DISODIUM EDTA, POLYACRYLATE CROSSPOLYMER-6, POLYSORBATE 20, T-BUTYL ALCOHOL, PHENOXYETHANOL, METHYLPROPANEDIOL, ETHYLHEXYLGLYCERIN, CAPRYLHYDROXAMIC ACID, PHENETHYL ALCOHOL, CAPRYLYL GLYCOL, SORBIC ACID, LIMONENE.
Sérum Progeskin (8 ml), Sérum Collagène Originel (8 ml), Sérum VG Tensil (8 ml), Sérum Elastine (8 ml), a La Grande Crème deluxe sample (5 ml) and the Biologique Recherche Royal Blue Travel Makeup Case.
Yes. Use them individually for targeted care, or layer up to four serums for a comprehensive routine for visible signs of aging.
For optimal results, apply Sérum Elastine in the morning and Sérum VG Tensil or Sérum Collagène Originel in the evening.
It is for anyone looking to discover or deepen their Biologique Recherche ritual, whether new to the line or a devoted fan.
Please see each individual product page for its full ingredient list.
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
For delivery and return information, view our policy.
Masters of Time brings together four Biologique Recherche Quintessential Serums, curated to address visible signs of aging: loss of firmness and elasticity, fine lines and dullness. Used together, the formulas work in synergy for a smoother, plumper, more luminous-looking complexion.
The set includes Sérum Progeskin (8 ml), Sérum Collagène Originel (8 ml), Sérum VG Tensil (8 ml), Sérum Elastine (8 ml) and a La Grande Crème deluxe sample (5 ml), presented in the Biologique Recherche Royal Blue Travel Makeup Case with gold detailing.
Use each serum on its own for targeted care, or layer up to four to build a complete routine for visible signs of aging.
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · A little reassurance
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
In Sérum Progeskin. A peptide included to help skin look firmer and smoother.
In Sérum Collagène Originel. A soy-derived ingredient included in the serum's targeted skin-conditioning formula.
In Sérum Élastine. A peptide associated with the elastin-focused complex and the serum's smoothing action.
Curious about your ingredients?
Explore La Matière
A little guidance. A more considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book your consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Biologique Recherche Masters of Time at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Biologique Recherche collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
A little care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. A little reminder, with your team still in reach.