Skinbetter Science Ampra Volumizing Macro HA Serum

Skinbetter Science Ampra Volumizing Macro HA Serum is a hyaluronic acid facial serum designed to replenish hydration, visibly plump the skin, and improve the appearance of facial contours, fine lines, and uneven texture.

Powered by proprietary HYAsync technology, it combines hyaluronic acid with alpha-lipoic acid to help protect hyaluronic acid from breakdown and sustain its hydrating benefits. Peptides, niacinamide, and moisture-supporting lipids complement the formula for skin that looks smoother, feels more supple, and appears visibly replenished.

A thoughtful addition when your skin’s needs include both dehydration and a gradual loss of fullness or definition.

Benefits

• Visibly fuller skin: Helps improve the appearance of plumpness and facial fullness.
• More defined contours: Supports a firmer, more lifted appearance, including through the lower face.
• Lasting hydration: Helps maintain moisture for comfortable, supple skin.
• Smoother texture: Softens the appearance of fine lines and uneven skin texture.
• Renewed luminosity: Helps improve the look of dull, tired-looking skin.
• Moisture barrier support: Combines niacinamide, squalane, and jojoba esters to help retain hydration.

Best For

Ampra is particularly suited to skin experiencing:

• Dehydration alongside a loss of visible fullness
• Early changes in firmness or facial definition
• Fine lines and uneven texture
• Dullness and a loss of luminosity

Suitable for all skin types, including mature skin. Choosing it should be guided by your skin’s current needs, rather than age alone.

How It Works

HYAsync technology links hyaluronic acid with alpha-lipoic acid. This combination is designed to help protect hyaluronic acid from rapid breakdown and sustain its presence and activity, supporting hydration and the appearance of plumper skin.

The formula also includes a biofermented complex, a peptide, and teff seed extract to help improve the look of smoothness and firmness. Niacinamide, squalane, and jojoba esters support the moisture barrier, helping skin retain the hydration it needs.

How to Use

1. Apply 1–2 pumps to clean, dry skin, morning and evening.
2. Smooth over the face, avoiding contact with the eyes.
3. Allow the serum to absorb fully before applying your next skincare product.
4. Follow with a moisturizer suited to your skin.
5. Complete your morning routine with broad-spectrum sunscreen.

Loshen & Crem’s Recommendation

We recommend considering Ampra when dehydration is accompanied by changes in skin fullness, firmness, or facial definition. These concerns often overlap, and a serum that addresses several of them can have a useful place in a well-chosen routine.

Pair it with a barrier-supporting moisturizer and consistent daily sun protection. Give your routine time, and introduce new products thoughtfully so you can understand how your skin responds.

If you already use several serums, our team can help you decide where Ampra belongs and whether it brings something useful to your existing routine.

Clinical Results

Skinbetter Science evaluated twice-daily use of Ampra in a 12-week, dermatologist-led clinical trial involving 65 women with visible volume loss and other signs of skin ageing.

The brand reports the following improvements in clinical grading at week 12:

These percentages describe changes in clinical grading, rather than the percentage of participants who experienced results. Individual results vary. Skinbetter Science’s published study summary

Ingredients

• HYAsync Technology — Hyaluronic Acid + Alpha-Lipoic Acid
  Designed to help protect hyaluronic acid from degradation and sustain its hydrating benefits, supporting visibly plumper skin.
• Hydrolyzed Yeast Extract + Polyglucuronic Acid
  A biofermented complex that supports hydration, smoother texture, and a firmer-looking complexion.
• Hydrolyzed Eragrostis Tef Seed Extract
  A teff seed extract that helps support the appearance of skin firmness and elasticity.
• Palmitoyl Tripeptide-38
  A peptide that helps improve the appearance of fine lines and supports smoother, fuller-looking skin.
• Niacinamide
  Supports the skin’s moisture barrier and helps improve the appearance of uneven tone and texture.
• Squalane + Jojoba Esters
  Help soften the skin, retain moisture, and support lasting comfort and suppleness.

Full Ingredient List

Aqua/Water/Eau, Glycerin, Isocetyl Stearoyl Stearate, Niacinamide, Pentylene Glycol, Jojoba Esters, Hydrolyzed Yeast Extract, Squalane, Glycol Palmitate, Cetyl Alcohol, Lecithin, Sodium Methyl Stearoyl Taurate, Sodium Thioctoyl/Formoyl Hyaluronate, Palmitoyl Tripeptide-38, Hydrolyzed Eragrostis Tef Seed Extract, Hydrolyzed Sodium Hyaluronate, Hydroxypropyl Cyclodextrin, Tetrasodium Glutamate Diacetate, Citric Acid, Xanthan Gum, Polyglucuronic Acid, Cetyl Hydroxyethylcellulose, Tocopherol, Potassium Sorbate, Sodium Benzoate, Phenoxyethanol.

Refer to your product packaging for the most current ingredient list.

Frequently Asked Questions

What is Skinbetter Science Ampra Volumizing Macro HA Serum?

Ampra is a hyaluronic acid facial serum that helps hydrate and visibly plump the skin while improving the appearance of fine lines, texture, and facial contours.

What makes Ampra different from a basic hyaluronic acid serum?

Ampra combines proprietary HYAsync technology with a peptide, a biofermented complex, niacinamide, and nourishing lipids. Its formula addresses hydration alongside the appearance of fullness, firmness, and texture.

What does Ampra feel like on the skin?

Skinbetter Science describes Ampra as a light, silky serum that absorbs easily without a heavy or sticky finish. Product details

How long does Ampra take to show results?

The brand reports visible improvements in plumpness from four weeks and lifting and lower-face contours from eight weeks, with further improvements through week 12. Individual results vary. Clinical information

Should I apply Ampra morning or evening?

Use Ampra both morning and evening. Apply 1–2 pumps to clean, dry skin and allow it to absorb before your next product. Finish your morning routine with sunscreen.

Does Ampra replace my moisturizer?

Ampra serves as the serum step in your routine. Follow it with a moisturizer chosen for your skin’s needs, particularly if your skin feels dry or tight.

Can I apply Ampra around my eyes?

Apply it to the face while avoiding contact with the eyes. Follow the directions on your packaging.

Where can I buy Skinbetter Science Ampra in Canada?

Shop Skinbetter Science Ampra through Loshen & Crem, a skincare boutique and facial studio in Edmonton serving clients across Canada. Our team can help you understand how it fits into your routine.