Your routine
Skinbetter ScienceAlphaRet Overnight Cream
Why it fits
AlphaRet Overnight Cream adds retinoid renewal at night, while Alto covers antioxidant care.

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Skincare Boutique & Facial Institute
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Explore La Crem rewardsDull, uneven or redness-prone skin
A daily antioxidant serum for skin that looks dull, uneven or prone to redness. Vitamins C and E, patented Allyl PQQ and a broad botanical blend help defend skin against free radicals, for a brighter, more even-looking complexion.
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5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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For delivery in Canada: Standard is $25 CAD below $149 CAD. Priority is $30 CAD below $249 CAD and free from $249 CAD on eligible orders. Adding an item excluded from free Priority removes free Priority for the entire order.
This selected item excludes the entire order from free Priority shipping in Canada. Standard is $25 CAD below $149 CAD and free from $149 CAD. A paid Priority upgrade is $30 CAD where available, including orders of $249 CAD or more.
Thresholds apply after discounts, before taxes and shipping. Product, ground-shipping and destination restrictions may apply. Available services and final charges appear at checkout.
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Skinbetter Science
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$144.00 CAD
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The skincare focus
A daily antioxidant serum for skin that looks dull, uneven or prone to redness. Vitamins C and E, patented Allyl PQQ and a broad botanical blend help defend skin against free radicals, for a brighter, more even-looking complexion.
Explore our ingredient glossarySkinbetter Science
The ingredients behind this formula—and what they bring to your skin.
Pyrroloquinoline Quinone Allyl Ester (Allyl PQQ)
Skinbetter Science's patented antioxidant technology, aimed at free radicals generated within the skin.
Tetrahexyldecyl Ascorbate
An oil-soluble form of vitamin C that helps defend skin against free radicals.
Tocopherol
Vitamin E, which helps protect skin and the formula from oxidation.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Pair with AlphaRet Overnight Cream at night and a daily sunscreen in the morning.
Your routine
AlphaRet Overnight Cream adds retinoid renewal at night, while Alto covers antioxidant care.
Your routine
Your daily moisturizer, applied after serums and before sunscreen.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
Skinbetter Science Alto Advanced Defense and Repair Serum is an antioxidant serum for morning and evening. It is built on the idea that skin faces free radicals from the environment and from within.
Vitamins C and E work with green tea, grape seed, cocoa, turmeric, olive and acai extracts to help defend against environmental stress. Patented Allyl PQQ adds antioxidant care aimed at free radicals generated within the skin.
Niacinamide, ceramides and hydrolyzed sodium hyaluronate help keep skin comfortable, while licorice, ginger and bisabolol help it look brighter and calmer. Its natural golden colour comes from the antioxidants themselves.
Antioxidant care is one of the most useful daily habits for long-term skin health. Alto goes well beyond a single vitamin C, with a wide range of antioxidants in one serum. It also soothes and hydrates, so it suits most skin. We like it as the everyday foundation of a routine.
Dull, uneven or redness-prone skin
Bring it down to the neck and décolleté, which show the effects of the environment as much as the face.
Aqua/Water/Eau, Butylene Glycol, Propanediol, Ethylhexyl Olivate, Cetearyl Alcohol, Chlorogenic Acids, Niacinamide, Lauryl Lactate, Dimethyl Isosorbide, Pyrroloquinoline Quinone Allyl Ester, Hydrolyzed Sodium Hyaluronate, Glycyrrhiza Glabra Root Extract / Licorice Root Extract, Tetrahexyldecyl Ascorbate, Ergothioneine, Taraxacum Officinale Rhizome / Root Extract – Dandelion Rhizome/Root Extract, Arabidopsis Thaliana Extract, Carnosine, Camellia Sinensis Leaf Extract, Vitis Vinifera Seed Extract / Grape Seed Extract, Theobroma Cacao Seed Extract / Cocoa Seed Extract, Curcuma Longa Root Extract / Turmeric Root Extract, Olea Europaea Fruit Extract / Olive Fruit Extract, Euterpe Oleracea Fruit Extract, Palmitoyl Tripeptide-1, Buddleja Officinalis Flower Extract, Coffea Arabica Seed Extract / Coffee Seed Extract, Crocus Sativus Callus Extract, Superoxide Dismutase, Ubiquinone, Plankton Extract, Micrococcus Lysate, Arginine, Zingiber Officinale Root Extract / Ginger Root Extract, Ceramide NP, Ceramide AP, Ceramide EOP, Linoleic Acid, Linolenic Acid, Ascorbic Acid, Bisabolol, Tocopherol, Tocopheryl Acetate, Cholesterol, Phytosphingosine, Jojoba Esters, Sodium PCA, Methyl Gluceth-20, Glycerin, Helianthus Annuus Seed Cera / Sunflower Seed Wax, Acacia Decurrens Flower Cera / Acacia Decurrens Flower Wax, Lecithin, Sodium Lauroyl Lactylate, Dicetyl Phosphate, Propanediol Dicaprylate / Caprate, Polyglycerin-3, Ceteth-20 Phosphate, Diisostearyl Malate, Xanthan Gum, Steareth-2, Acacia Senegal Gum, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Carbomer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Maltodextrin, Ricinoleth-40, Sodium Hydroxide, Citric Acid, Sodium Phytate, Ethylhexylglycerin, Phenoxyethanol, Ethylhexyl Palmitate, Alcohol, Lactic Acid, Pentylene Glycol, Sorbitan Isostearate, Tribehenin.
It contains vitamin C, but as part of a much broader antioxidant formula with vitamin E, Allyl PQQ and botanical extracts.
Both. Apply after cleansing and before moisturizer.
No. Antioxidants complement sunscreen. Keep wearing a daily sunscreen.
Yes. The colour can range from yellow-beige to golden yellow, from its naturally coloured antioxidant ingredients. It contains no dyes.
It contains moisturizing ingredients, but most skin benefits from a moisturizer on top.
For delivery and return information, view our policy.
A daily antioxidant serum for skin that looks dull, uneven or prone to redness. Vitamins C and E, patented Allyl PQQ and a broad botanical blend help defend skin against free radicals, for a brighter, more even-looking complexion.
Skinbetter Science Alto Advanced Defense and Repair Serum is an antioxidant serum for morning and evening. It is built on the idea that skin faces free radicals from the environment and from within.
Vitamins C and E work with green tea, grape seed, cocoa, turmeric, olive and acai extracts to help defend against environmental stress. Patented Allyl PQQ adds antioxidant care aimed at free radicals generated within the skin.
Niacinamide, ceramides and hydrolyzed sodium hyaluronate help keep skin comfortable, while licorice, ginger and bisabolol help it look brighter and calmer. Its natural golden colour comes from the antioxidants themselves.
Antioxidant care is one of the most useful daily habits for long-term skin health. Alto goes well beyond a single vitamin C, with a wide range of antioxidants in one serum. It also soothes and hydrates, so it suits most skin. We like it as the everyday foundation of a routine.
Aqua/Water/Eau, Butylene Glycol, Propanediol, Ethylhexyl Olivate, Cetearyl Alcohol, Chlorogenic Acids, Niacinamide, Lauryl Lactate, Dimethyl Isosorbide, Pyrroloquinoline Quinone Allyl Ester, Hydrolyzed Sodium Hyaluronate, Glycyrrhiza Glabra Root Extract / Licorice Root Extract, Tetrahexyldecyl Ascorbate, Ergothioneine, Taraxacum Officinale Rhizome / Root Extract – Dandelion Rhizome/Root Extract, Arabidopsis Thaliana Extract, Carnosine, Camellia Sinensis Leaf Extract, Vitis Vinifera Seed Extract / Grape Seed Extract, Theobroma Cacao Seed Extract / Cocoa Seed Extract, Curcuma Longa Root Extract / Turmeric Root Extract, Olea Europaea Fruit Extract / Olive Fruit Extract, Euterpe Oleracea Fruit Extract, Palmitoyl Tripeptide-1, Buddleja Officinalis Flower Extract, Coffea Arabica Seed Extract / Coffee Seed Extract, Crocus Sativus Callus Extract, Superoxide Dismutase, Ubiquinone, Plankton Extract, Micrococcus Lysate, Arginine, Zingiber Officinale Root Extract / Ginger Root Extract, Ceramide NP, Ceramide AP, Ceramide EOP, Linoleic Acid, Linolenic Acid, Ascorbic Acid, Bisabolol, Tocopherol, Tocopheryl Acetate, Cholesterol, Phytosphingosine, Jojoba Esters, Sodium PCA, Methyl Gluceth-20, Glycerin, Helianthus Annuus Seed Cera / Sunflower Seed Wax, Acacia Decurrens Flower Cera / Acacia Decurrens Flower Wax, Lecithin, Sodium Lauroyl Lactylate, Dicetyl Phosphate, Propanediol Dicaprylate / Caprate, Polyglycerin-3, Ceteth-20 Phosphate, Diisostearyl Malate, Xanthan Gum, Steareth-2, Acacia Senegal Gum, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Carbomer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Maltodextrin, Ricinoleth-40, Sodium Hydroxide, Citric Acid, Sodium Phytate, Ethylhexylglycerin, Phenoxyethanol, Ethylhexyl Palmitate, Alcohol, Lactic Acid, Pentylene Glycol, Sorbitan Isostearate, Tribehenin.
Please refer to the packaging of your product for the most up-to-date ingredient list.
Caution: For external use only. Avoid contact with eyes; if contact occurs, rinse thoroughly with water. If irritation persists, discontinue use and consult a physician.
Explore Skinbetter Science at Loshen & Crem, our skin-health boutique and facial studio in Edmonton. We ship across Canada, and our team is happy to help you find the right routine.
The care behind your order
A few helpful details, before your next delivery.
Track your orderDelivery
For delivery in Canada: Standard is $25 CAD below $149 CAD. Priority is $30 CAD below $249 CAD and free from $249 CAD on eligible orders. Adding an item excluded from free Priority removes free Priority for the entire order.
This selected item excludes the entire order from free Priority shipping in Canada. Standard is $25 CAD below $149 CAD and free from $149 CAD. A paid Priority upgrade is $30 CAD where available, including orders of $249 CAD or more.
Thresholds apply after discounts, before taxes and shipping. Product, ground-shipping and destination restrictions may apply. Available services and final charges appear at checkout.
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Skinbetter Science's patented antioxidant technology, aimed at free radicals generated within the skin.
An oil-soluble form of vitamin C that helps defend skin against free radicals.
Vitamin E, which helps protect skin and the formula from oxidation.
Vitamin B3, which helps hydration and the look of skin clarity.
Helps brighten the look of uneven tone.
A soothing pair that helps calm the look of redness.
Curious about your ingredients?
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Expert guidance. A considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Skinbetter Science Alto Advanced Defense and Repair Serum at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Skinbetter Science collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.
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