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Skinbetter Science Mystro Revive Renewing Serum is a nourishing facial serum for dry, mature skin experiencing changes associated with perimenopause and menopause. It helps improve the appearance of firmness, elasticity, fine lines, and crepey texture while supporting hydration and the skin’s moisture barrier.
As your skin’s needs evolve, your routine can evolve with them. Mystro Revive brings together botanical technologies, replenishing lipids, and antioxidants to help skin feel more comfortable, look smoother, and regain a sense of suppleness.
Benefits
- Nourishes dry skin: Helps replenish moisture and restore softness and comfort.
- Supports visible firmness: Improves the appearance of elasticity and skin resilience.
- Smooths crepey texture: Helps soften the look of finely wrinkled, uneven skin.
- Reduces the appearance of lines: Supports a smoother-looking complexion.
- Reinforces the moisture barrier: Combines cholesterol and ceramides to help limit moisture loss.
- Provides antioxidant support: Helps defend against oxidative stress that can contribute to visible skin changes.
- Restores luminosity: Helps dry, dull skin appear more refreshed.
Best For
- Skin experiencing changes during perimenopause or menopause
- Dry to very dry, mature skin
- Crepey texture and a loss of suppleness
- Reduced firmness and elasticity
- Fine lines, wrinkles, and dullness
- Dry skin needing additional moisture barrier support
How It Works
Mystro Revive combines P.A.T.H.[13], a proprietary blend of 13 plant adaptogens, with TAP antioxidant technology. These technologies are designed to support skin balance and address visible changes associated with perimenopause and menopause. Skinbetter Science’s technology overview
Cholesterol, ceramides, evening primrose oil, and black currant seed oil complement the formula by replenishing lipids and supporting moisture retention. Together, these ingredients help improve skin comfort, softness, and the appearance of resilience.
How to Use
- Apply 1–2 pumps to cleansed skin, morning and evening.
- Massage thoroughly over the face, including around the hairline and eyebrows, while avoiding contact with the eyes.
- Allow the serum to absorb before applying additional products.
- Follow with a moisturizer suited to your skin’s needs.
- Complete your morning routine with broad-spectrum sunscreen.
Follow the directions on your product packaging if they differ.
Loshen & Crem’s Recommendation
When a familiar routine no longer leaves your skin feeling comfortable, it may be time to reassess what your skin needs. We recommend considering Mystro Revive when increased dryness is accompanied by changes in firmness, texture, or suppleness during perimenopause or menopause.
Build your routine around a gentle cleanser, this nourishing serum, and a barrier-supporting moisturizer. A richer cream in the evening can be particularly welcome when skin feels persistently dry.
Our approach is to make each step useful. If you already use several treatment products, our team can help you decide where Mystro Revive belongs and how to keep your routine comfortable and consistent.
Clinical Results
A 16-week, multicentre clinical study led by dermatologists and plastic surgeons evaluated twice-daily use in 53 women aged 46 and older experiencing perimenopause or menopause.
At week 16, Skinbetter Science reports:
| Assessed concern | Reported improvement |
|---|---|
| Appearance of crepey skin | 32% |
| Appearance of lines and wrinkles | 22% |
| Skin hydration* | 60% |
| Skin barrier integrity* | 27% |
Hydration and transepidermal water loss were measured using non-invasive methods in a subset of 44 participants. Percentages represent reported mean changes from baseline, rather than the percentage of participants who experienced results.
The serum was evaluated within a skincare routine. Individual results vary. Skinbetter Science’s clinical summary
Ingredients
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P.A.T.H.[13] Technology
A proprietary botanical complex selected to support skin balance and improve the appearance of dryness, fine lines, and other visible changes associated with hormonal transitions. -
TAP Technology — Allyl PQQ
An antioxidant technology that helps protect against free radical damage and its visible effects on the skin. Skinbetter Science’s ingredient information -
Cholesterol + Ceramides EOP and NP
Lipids that help reinforce the moisture barrier, retain hydration, and support softer, more comfortable skin. -
Evening Primrose Oil + Black Currant Seed Oil
Nourishing oils that help replenish dry skin and support suppleness. -
Niacinamide
Helps support the skin’s moisture barrier and improve the appearance of uneven tone and texture. -
Astaxanthin, Superoxide Dismutase + Ergothioneine
An antioxidant combination that helps defend against oxidative stress and supports overall skin quality.
Full Ingredient List
Aqua/Water/Eau, Copaifera Officinalis Resin/Balsam Copaiba Resin, Glycerin, Propanediol, Cholesterol, Oenothera Biennis Oil/Evening Primrose Oil, Ribes Nigrum Seed Oil/Black Currant Seed Oil, Glyceryl Stearate Citrate, Butylene Glycol, Niacinamide, Ethyl Oleate, Behenyl Alcohol, C12-16 Alcohols, Ammonium Polyacryloyldimethyl Taurate, Panax Ginseng Root Extract, Curcuma Longa Root Extract/Turmeric Root Extract, Sophora Japonica Flower Extract, Echinacea Purpurea Extract, Vitis Vinifera Flower Cell Extract/Grape Flower Cell Extract, Chamomilla Recutita Flower Extract/Matricaria Flower Extract, Magnolia Officinalis Bark Extract, Theobroma Cacao Extract/Cocoa Extract, Hippophae Rhamnoides Kernel Extract, Humulus Lupulus Extract/Hops Extract, Ceramide EOP, Ceramide NP, Potassium Cetyl Phosphate, Astaxanthin, Dimethicone, Superoxide Dismutase, Ricinoleth-40, Sodium Hydroxide, Sodium Starch Octenylsuccinate, Silica, Cyclodextrin, Palmitic Acid, Phenethyl Alcohol, Ascorbic Acid, Ergothioneine, Thioctic Acid, Hydrogenated Lecithin, Hydrolyzed Sodium Hyaluronate, Caprylyl Glycol, Pyrroloquinoline Quinone Allyl Ester, Maltodextrin, Xanthan Gum, Phytic Acid, Ethylhexylglycerin, Tocopherol, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Phenoxyethanol.
Refer to your product packaging for the most current ingredient list.
Frequently Asked Questions
What is Skinbetter Science Mystro Revive Renewing Serum?
Mystro Revive is a nourishing serum designed for visible skin changes associated with perimenopause and menopause, including dryness, reduced firmness, crepey texture, and fine lines.
Why consider Mystro Revive during perimenopause or menopause?
It addresses several concerns that can occur together during this transition: increased dryness, a less resilient moisture barrier, and changes in texture and elasticity. Its formula combines nourishing lipids with botanical technologies and antioxidant support.
What is the difference between Mystro Revive and Mystro Active Balance Serum?
Mystro Revive focuses on dry, mature skin experiencing changes associated with perimenopause and menopause and has a richer, creamy texture. Mystro Active Balance focuses on concerns such as visible redness, uneven pigmentation, texture, and pores. Compare the Mystro formulas
Does Mystro Revive replace estrogen or balance hormones?
Mystro Revive is topical skincare for visible skin concerns. It is not a hormone replacement treatment and should not be understood as restoring estrogen levels.
How long does Mystro Revive take to show results?
Skinbetter Science reports visible improvements in elasticity, lines, wrinkles, and overall skin quality from eight weeks, with continued improvements through week 16. Individual results vary. Clinical information
Do I still need a moisturizer?
For dry or very dry skin, follow Mystro Revive with a moisturizer. The serum provides targeted care, while your moisturizer adds comfort and helps maintain hydration.
Does Mystro Revive have a scent?
The formula contains no added fragrance, but its botanical ingredients and oils give it a natural scent. Fragrance-free does not necessarily mean scent-free. Formula details
Where can I buy Mystro Revive Renewing Serum in Canada?
Shop Mystro Revive through Loshen & Crem, a skincare boutique and facial studio in Edmonton serving clients across Canada. Our team can help you choose products that suit your skin’s changing needs.
Complimentary shipping from $149 and priority shipping from $249
Available at our Edmonton Boutique
Ship to Canada only
Pickup available at Loshen & Crem
Usually ready in 24 hours

Skinbetter Science Mystro Revive Renewing Serum
30 ml
Loshen & Crem
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
Returns & Refunds
At Loshen & Crem, we understand that sometimes, even the most carefully chosen product might not be "the one."
- Returns: You have 30 days from delivery to return any unopened and unused products in perfect condition—just as they arrived.
- Refunds: If your return reaches us within 30 days from delivery, you’ll have the choice between a refund or store credit (your preference, naturellement). After 30 days, store credit is your only option. Beyond 40 days, refunds and credits are no longer possible.
Final Sale Items
Promotional Items: Products purchased at a discount during promotions are considered final sale and cannot be returned or exchanged.
Final Markdown Items: Items marked as Final Markdown are non-returnable, non-exchangeable, and non-refundable.
Hair Care Products, Nail Polishes, Nail Treatments & Makeup: Due to hygiene and quality control standards, all purchases in these categories are final and cannot be returned, exchanged, or refunded.
Electrical Devices : Electrical devices are final sale for change-of-mind returns — we're unable to offer returns, exchanges, or refunds if you simply change your mind. If a device arrives defective or develops a fault, please see our Warranties section below for manufacturer warranty support.
Seasonal Items: Seasonal and limited-edition items are final sale and cannot be returned, exchanged, or refunded.
Gift Cards: Gift cards are final sale and non-refundable.
Please note: Final sale means no exchanges, refunds, or credits are available.
In-Store Purchases: For products purchased at our Edmonton boutique, our return policy remains consistent. You are invited to return items directly to the store, allowing you to bypass shipping concerns. Kindly note that our opening hours may vary. For the latest information, please click Loshen & Crem Opening hours.
Final Sale on Store Credit Purchases: Any items purchased using store credit issued from a previous return will be considered final sale. These items are not eligible for further returns or exchanges.
Shipping Policy
Shipping Rates and Delivery Times
All amounts are in Canadian dollars unless otherwise noted. Order thresholds are calculated after discounts, before taxes and shipping.
Standard Shipping — Estimated delivery: 3–7 business days*
Orders $149 and over: FREE
Orders $148.99 and under: $25
Priority Shipping — Estimated delivery: 1–2 business days*
Orders $249 and over: FREE
Orders $248.99 and under: $30
Processing: Orders placed before 2 p.m. Mountain Time, Monday through Friday, ship the same day, excluding holidays. Orders placed after the cutoff, on weekends, or on holidays ship the next business day.
Delivery estimates and remote destinations: Delivery estimates begin once your order has shipped. Remote destinations may require additional transit time.
Product exclusions — Canada: Heavy items, including candles and one-litre shampoos, and selected promotional items are eligible for Standard shipping only, even when your order meets the complimentary Priority-shipping threshold. Any applicable shipping charges will be displayed at checkout.
United States
Complimentary Priority shipping is available on orders of $350 USD or more. Orders below this threshold are subject to a $48.95 CAD shipping fee. Promotional shipping rates may apply during MistleGlow.
The following are excluded from our U.S. shipping zone: Alaska, Hawaii, Armed Forces Americas, Armed Forces Europe, and Armed Forces Pacific.
West Coast: 2–3 business days
Midwest: 2–3 business days
East Coast: 3–4 business days
Please note that additional processing time may apply, and deliveries to remote areas may take longer.
Shipping rates are subject to change without notice. Delivery times are estimates and cannot be guaranteed, as carrier delays may occur.
Shipping Address Details
For a smooth delivery, please provide all relevant information, including buzzer codes, directional suffixes (North, South, etc.), or special instructions.
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Address Changes: Once your package has left our warehouse, address updates cannot be made. If you need to make changes before dispatch, email us at info@loshen.ca with your order details.
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Carrier Fees: Any changes made with the courier after dispatch will incur a $32 CAD fee, and the Free Express Shipping option will be deducted from your La Crème Points account.
Tracking Your Order
All shipments include tracking information, so you can follow your package from our warehouse to your door. A confirmation email with your tracking number will be sent once your order is dispatched.
Damaged or Lost Packages
- Damaged Parcels: If your order arrives damaged, please contact us at info@loshen.ca with photos and details. We’ll work to resolve the issue promptly.
- Lost or Stolen Packages: If your package is marked "delivered" but hasn’t arrived, please contact the carrier directly to file a claim.
Tips to Avoid Lost or Stolen Packages:
- Opt for a signature upon receipt (required for orders over $350 CAD).
- Have your package delivered to your workplace.
- If you’re not home on the expected delivery date, ask a neighbor to receive your package.
Unclaimed Parcels
If your package is returned to us unclaimed, we’ll issue a refund minus a $29.95 CAD return shipping fee.
Free Samples
We believe every order deserves a little extra care! Expect 1–3 complimentary samples selected by our Skincare Specialists to perfectly complement your order.
Loyalty Rewards: La Crem Points
Earn La Crème Points with every purchase and redeem them for future orders. From time to time, we also offer Free Gifts With Purchase (GWP) for select brands, but these are available only while supplies last.
At Loshen & Crem, we aim to deliver excellence at every step of your skincare journey, with care and a touch of elegance. Questions? Don’t hesitate to reach out—we’re always happy to assist!
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