







Skinbetter Science Mystro Active Balance Serum
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Daily balancing care for redness, uneven texture, and dullness
Skinbetter Science Mystro Active Balance Serum is a daily facial serum that helps improve the appearance of redness associated with dryness, rough texture, visible pores, dullness, and uneven pigmentation.
Its proprietary P.A.T.H. Technology combines plant-based adaptogens with antioxidants and moisturizing ingredients to support the skin’s natural ability to maintain balance. With consistent use, skin looks smoother, more even, and more luminous.
A considered choice when several concerns appear together and your skin needs a more balanced approach.
Benefits:
- Helps reduce the appearance of redness associated with dry skin
- Refines rough texture for smoother-looking skin
- Improves the appearance of visible pores
- Promotes a more even-looking skin tone
- Restores luminosity to a dull-looking complexion
- Supports moisture retention and skin suppleness
Best for:
- Visible redness associated with dryness
- Rough or uneven skin texture
- Dullness and lack of luminosity
- Enlarged-looking pores and uneven pigmentation
- Those seeking a daily serum that addresses several visible concerns together
How it works:
P.A.T.H. stands for Plant Adaptogens Targeting Homeostasis. This proprietary blend of plant extracts is designed to support the skin’s natural ability to adapt to stress and maintain balance.
Antioxidants complement the formula, while niacinamide, hydrolyzed sodium hyaluronate, and squalane help maintain moisture. Together, these ingredients support a smoother, more comfortable, and more even-looking complexion.
Clinical results:
A 12-week, dermatologist-led clinical trial evaluated Mystro Active Balance Serum in 53 participants with mild-to-severe photodamaged skin. Participants used the serum twice daily alongside a gentle cleanser, moisturizer, and daily sunscreen.
The Canadian manufacturer reports the following average improvements in overall visible skin quality, measured from baseline:
| Time using Mystro | Average improvement |
|---|---|
| 2 weeks | 13% |
| 4 weeks | 22% |
| 8 weeks | 30% |
| 12 weeks | 39% |
Overall skin quality combines the assessment of redness, texture, dullness, visible pores, and uneven pigmentation. Individual results vary. Canadian clinical results
In participant feedback, 98% reported feeling more confident in their skin’s appearance after 12 weeks. Manufacturer’s study details
How to use:
- Apply morning and evening after cleansing.
- Dispense up to one pump onto fingertips and dot over the forehead, cheeks, and chin.
- Gently massage outward from the centre of the face until thoroughly absorbed.
- Blend carefully around the hairline and eyebrows, where serum may remain visible.
- Allow the serum to absorb completely before applying additional products.
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Follow with moisturizer as needed and sun protection during the day.
May also be applied to the neck and décolleté.
For external use only. Avoid contact with the eyes; rinse thoroughly with water if contact occurs. Discontinue use if irritation or a rash develops. Keep out of reach of children.
Loshen & Crem’s recommendation:
We recommend Mystro when redness, uneven texture, and dullness seem to arrive together. It offers a thoughtful way to address the overall appearance of your skin within a simple daily routine.
Pair it with a gentle cleanser, a barrier-supporting moisturizer, and consistent sun protection. Introduce one new product at a time, and give your skin space to respond. Our facialists can help you decide where Mystro belongs alongside the products you already enjoy.
Ingredients:
- P.A.T.H. Technology: A proprietary blend of plant-based adaptogens designed to support skin balance and improve overall visible skin quality.
- Alpha Lipoic Acid — Thioctic Acid: An antioxidant that helps defend against the visible effects of environmental exposure.
- Astaxanthin: An algae-derived antioxidant that also contributes to the formula’s natural colour.
- Ergothioneine: Provides additional antioxidant support.
- Isosorbide Dicaprylate: Helps support moisture balance and the skin barrier.
- Niacinamide: A form of vitamin B3 that helps maintain skin moisture.
- Hydrolyzed Sodium Hyaluronate: Helps retain hydration for more supple-feeling skin.
- Squalane: An emollient that supports moisture retention and softness.
Full ingredient list:
Aqua/Water, Copaifera Officinalis (Balsam Copaiba) Resin, Glycerin, Butylene Glycol, Propanediol, Polyglyceryl-3 Distearate, Isosorbide Dicaprylate, Cetearyl Glucoside, Ethoxydiglycol, Diheptyl Succinate, Squalane, Niacinamide, Panax Notoginseng Root Extract, Theobroma Cacao (Cocoa) Leaf Cell Extract, Chamomilla Recutita (Matricaria) Flower Extract, Magnolia Officinalis Bark Extract, Echinacea Purpurea Extract, Sophora Japonica Bud Extract, Humulus Lupulus (Hops) Extract, Curcuma Longa (Turmeric) Root Extract, Hydrolyzed Sodium Hyaluronate, Haematococcus Pluvialis Extract, Astaxanthin, Ergothioneine, Thioctic Acid, Sorbitan Olivate, Tocopherol, Caprylic/Capric Triglyceride, Capryloyl Glycerin/Sebacic Acid Copolymer, Sodium Stearoyl Glutamate, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Glyceryl Stearate Citrate, Tribehenin, Cetearyl Alcohol, Acacia Senegal Gum, Hydroxyethylcellulose, Xanthan Gum, Ethylhexylglycerin, Phenethyl Alcohol, Phenoxyethanol, Citric Acid, Phytic Acid, Sodium Hydroxide.
Please refer to your product packaging for the most current ingredient list.
Thoughtful packaging:
An airless bottle helps protect the formula during use. The twist-up pump controls dispensing and is designed to help you access more of the serum inside.
Frequently asked questions:
Is Mystro Active Balance Serum a retinol serum?
No. Mystro uses P.A.T.H. Technology, antioxidants, and moisturizing ingredients. Its listed formula does not contain a retinoid.
What is the difference between Mystro Active Balance and Mystro Revive?
Active Balance focuses on visible redness, texture, dullness, pores, and uneven pigmentation. Mystro Revive Renewing Serum has a richer texture and is formulated for dryness, loss of elasticity, and other visible skin changes associated with perimenopause and menopause. Skinbetter Science’s comparison
How does Mystro differ from Alto Advanced?
Mystro centres on supporting skin balance and improving overall visible skin quality. Alto Advanced focuses on antioxidant defense against internal and environmental free radicals. Your skin’s concerns and existing routine can help determine which to prioritize. Manufacturer’s guidance
How quickly can I expect results?
The manufacturer reports measurable improvements in overall visible skin quality after two weeks, with continued improvements through twelve weeks of twice-daily use. Results depend on the individual and consistent use.
Is Mystro non-comedogenic?
Yes. Skinbetter Science identifies Mystro Active Balance Serum as non-comedogenic.
Should I apply it before or after moisturizer?
Apply after cleansing and before moisturizer. Let it absorb completely before continuing your routine.
Complimentary shipping from $149 and priority shipping from $249
Available at our Edmonton Boutique
Ship to Canada only
Pickup available at Loshen & Crem
Usually ready in 24 hours

Skinbetter Science Mystro Active Balance Serum
30 ml
Loshen & Crem
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
Returns & Refunds
At Loshen & Crem, we understand that sometimes, even the most carefully chosen product might not be "the one."
- Returns: You have 30 days from delivery to return any unopened and unused products in perfect condition—just as they arrived.
- Refunds: If your return reaches us within 30 days from delivery, you’ll have the choice between a refund or store credit (your preference, naturellement). After 30 days, store credit is your only option. Beyond 40 days, refunds and credits are no longer possible.
Final Sale Items
Promotional Items: Products purchased at a discount during promotions are considered final sale and cannot be returned or exchanged.
Final Markdown Items: Items marked as Final Markdown are non-returnable, non-exchangeable, and non-refundable.
Hair Care Products, Nail Polishes, Nail Treatments & Makeup: Due to hygiene and quality control standards, all purchases in these categories are final and cannot be returned, exchanged, or refunded.
Electrical Devices : Electrical devices are final sale for change-of-mind returns — we're unable to offer returns, exchanges, or refunds if you simply change your mind. If a device arrives defective or develops a fault, please see our Warranties section below for manufacturer warranty support.
Seasonal Items: Seasonal and limited-edition items are final sale and cannot be returned, exchanged, or refunded.
Gift Cards: Gift cards are final sale and non-refundable.
Please note: Final sale means no exchanges, refunds, or credits are available.
In-Store Purchases: For products purchased at our Edmonton boutique, our return policy remains consistent. You are invited to return items directly to the store, allowing you to bypass shipping concerns. Kindly note that our opening hours may vary. For the latest information, please click Loshen & Crem Opening hours.
Final Sale on Store Credit Purchases: Any items purchased using store credit issued from a previous return will be considered final sale. These items are not eligible for further returns or exchanges.
Shipping Policy
Shipping Rates and Delivery Times
All amounts are in Canadian dollars unless otherwise noted. Order thresholds are calculated after discounts, before taxes and shipping.
Standard Shipping — Estimated delivery: 3–7 business days*
Orders $149.01 and over: FREE
Orders $149 and under: $25
Priority Shipping — Estimated delivery: 1–2 business days*
Orders $249.01 and over: FREE
Orders $249 and under: $30
Processing: Orders placed before 2 p.m. Mountain Time, Monday through Friday, ship the same day, excluding holidays. Orders placed after the cutoff, on weekends, or on holidays ship the next business day.
Delivery estimates and remote destinations: Delivery estimates begin once your order has shipped. Remote destinations may require additional transit time.
Product exclusions — Canada: Heavy items, including candles and one-litre shampoos, and selected promotional items are eligible for Standard shipping only, even when your order meets the complimentary Priority-shipping threshold. Any applicable shipping charges will be displayed at checkout.
United States
Complimentary Priority shipping is available on orders of $350 USD or more. Orders below this threshold are subject to a $48.95 CAD shipping fee. Promotional shipping rates may apply during MistleGlow.
The following are excluded from our U.S. shipping zone: Alaska, Hawaii, Armed Forces Americas, Armed Forces Europe, and Armed Forces Pacific.
West Coast: 2–3 business days
Midwest: 2–3 business days
East Coast: 3–4 business days
Please note that additional processing time may apply, and deliveries to remote areas may take longer.
Shipping rates are subject to change without notice. Delivery times are estimates and cannot be guaranteed, as carrier delays may occur.
Shipping Address Details
For a smooth delivery, please provide all relevant information, including buzzer codes, directional suffixes (North, South, etc.), or special instructions.
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Address Changes: Once your package has left our warehouse, address updates cannot be made. If you need to make changes before dispatch, email us at info@loshen.ca with your order details.
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Carrier Fees: Any changes made with the courier after dispatch will incur a $32 CAD fee, and the Free Express Shipping option will be deducted from your La Crème Points account.
Tracking Your Order
All shipments include tracking information, so you can follow your package from our warehouse to your door. A confirmation email with your tracking number will be sent once your order is dispatched.
Damaged or Lost Packages
- Damaged Parcels: If your order arrives damaged, please contact us at info@loshen.ca with photos and details. We’ll work to resolve the issue promptly.
- Lost or Stolen Packages: If your package is marked "delivered" but hasn’t arrived, please contact the carrier directly to file a claim.
Tips to Avoid Lost or Stolen Packages:
- Opt for a signature upon receipt (required for orders over $350 CAD).
- Have your package delivered to your workplace.
- If you’re not home on the expected delivery date, ask a neighbor to receive your package.
Unclaimed Parcels
If your package is returned to us unclaimed, we’ll issue a refund minus a $29.95 CAD return shipping fee.
Free Samples
We believe every order deserves a little extra care! Expect 1–3 complimentary samples selected by our Skincare Specialists to perfectly complement your order.
Loyalty Rewards: La Crem Points
Earn La Crème Points with every purchase and redeem them for future orders. From time to time, we also offer Free Gifts With Purchase (GWP) for select brands, but these are available only while supplies last.
At Loshen & Crem, we aim to deliver excellence at every step of your skincare journey, with care and a touch of elegance. Questions? Don’t hesitate to reach out—we’re always happy to assist!
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