Skincare Boutique & Facial Institute
Skincare Boutique & Facial Institute
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Explore La Crem rewardsFor experienced skincare users. One of the most potent dark-spot treatments available for home use. Please speak with our team before starting.
Discover the formula & ingredientsPickup in Edmonton
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5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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For delivery in Canada: Standard is $25 CAD below $149 CAD. Priority is $30 CAD below $249 CAD and free from $249 CAD on eligible orders. Adding an item excluded from free Priority removes free Priority for the entire order.
This selected item excludes the entire order from free Priority shipping in Canada. Standard is $25 CAD below $149 CAD and free from $149 CAD. A paid Priority upgrade is $30 CAD where available, including orders of $249 CAD or more.
Thresholds apply after discounts, before taxes and shipping. Product, ground-shipping and destination restrictions may apply. Available services and final charges appear at checkout.
Selected with care.
mesoestetic
Your ritual begins with the right choice.
$224.00 CAD
Taxes calculated at checkout.
The skincare focus
For experienced skincare users. One of the most potent dark-spot treatments available for home use. Please speak with our team before starting.
Explore our ingredient glossarymesoestetic
The ingredients behind this formula—and what they bring to your skin.
Tranexamic acid
helps visibly reduce dark spots that appear with triggers such as sun exposure and hormonal changes.
Tyr control complex
the combination of kojic acid with an innovative peptide and an amino acid helps visibly fade dark spots and even the look of skin tone.
Niacinamide
helps even the look of skin tone and reduce the appearance of dark spots.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Explore another step in your face-care routine.
Your routine
Intensive care for the look of redness and the feeling of irritation, providing the sensation of instant relief. Reduces skin sensitivity and strengthens the skin's defences against external aggressors, and comforts skin when it feels sensitized.
Your routine
Creamy cleansing foam with AHA’s. Renewer, rebalancing and anti-pollution. Normal and combination skin.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
For experienced skincare users. One of the most potent dark-spot treatments available for home use. Please speak with our team before starting.
Intensive dark-spot corrector for daily use that visibly reduces dark spots and the look of excess pigmentation. Its ultra-light texture allows you to apply it before your usual cream.
Call us on 780-722-9086 or email us at info@loshen.ca. Our Skin Experts will guide you to the perfect selection of this advanced cosmeceutical product.
Aqua, Bis-PEG-12 Dimethicone, Butylene Glycol, Hydroxyethyl Urea, Niacinamide, Tranexamic Acid, Mandelic Acid, Polymethylsilsesquioxane, Lactic Acid, Sodium Citrate, Sodium Hydroxide, Kojic Acid, Plankton Extract, Bacillus Ferment, Acetyl Glycyl beta-Alanine, Glycogen, Ethylhexylglycerin, Propylene Glycol, Glycerin, Salicylic Acid, Citric Acid, Xanthan Gum, Polyacrylate Crosspolymer-11, Aminoethylphosphinic Acid, Disodium EDTA, Sclerotium Gum, Lecithin, Pullulan, Pentylene Glycol, Sodium Hyaluronate Crosspolymer-2, Silica, Potassium Sorbate, Sodium Metabisulfite, Phenoxyethanol, Parfum. Please note that ingredients may change from time to time. You will find an updated list of ingredients on the package.
Mesoestetic products are designed to deliver real, visible results on dark spots and uneven tone. These are powerful, professional-grade treatments—not your everyday skincare—and they require a tailored approach to ensure safety and effectiveness. While we respect recommendations from other professionals, please note that if you purchase Mesoestetic from Loshen & Crem without a direct recommendation from our own team, we cannot accept returns, refunds, or credits in the event of sensitivity or an allergic reaction. Our professionals take great care to assess each client’s skin needs, knowing that these active ingredients, though transformative, may not be suitable for everyone. As an authorized retailer, Loshen & Crem provides only the latest formulations to ensure you’re getting the best results possible. Thank you for trusting Loshen & Crem with your skincare journey. We’re here to support you with expertise, care, and a commitment to helping you achieve safe, beautiful results.
For delivery and return information, view our policy.
For experienced skincare users. One of the most potent dark-spot treatments available for home use. Please speak with our team before starting.
Intensive dark-spot corrector for daily use that visibly reduces dark spots and the look of excess pigmentation. Its ultra-light texture allows you to apply it before your usual cream.
Call us on 780-722-9086 or email us at info@loshen.ca. Our Skin Experts will guide you to the perfect selection of this advanced cosmeceutical product.
Precautions for use
Wash hands after application to avoid direct contact with eyes and mucous membranes, if necessary, rinse with plenty of water. Keep out of the reach of children.
Aqua, Bis-PEG-12 Dimethicone, Butylene Glycol, Hydroxyethyl Urea, Niacinamide, Tranexamic Acid, Mandelic Acid, Polymethylsilsesquioxane, Lactic Acid, Sodium Citrate, Sodium Hydroxide, Kojic Acid, Plankton Extract, Bacillus Ferment, Acetyl Glycyl beta-Alanine, Glycogen, Ethylhexylglycerin, Propylene Glycol, Glycerin, Salicylic Acid, Citric Acid, Xanthan Gum, Polyacrylate Crosspolymer-11, Aminoethylphosphinic Acid, Disodium EDTA, Sclerotium Gum, Lecithin, Pullulan, Pentylene Glycol, Sodium Hyaluronate Crosspolymer-2, Silica, Potassium Sorbate, Sodium Metabisulfite, Phenoxyethanol, Parfum. Please note that ingredients may change from time to time. You will find an updated list of ingredients on the package.
Mesoestetic products are designed to deliver real, visible results on dark spots and uneven tone. These are powerful, professional-grade treatments—not your everyday skincare—and they require a tailored approach to ensure safety and effectiveness.
While we respect recommendations from other professionals, please note that if you purchase Mesoestetic from Loshen & Crem without a direct recommendation from our own team, we cannot accept returns, refunds, or credits in the event of sensitivity or an allergic reaction. Our professionals take great care to assess each client’s skin needs, knowing that these active ingredients, though transformative, may not be suitable for everyone.
As an authorized retailer, Loshen & Crem provides only the latest formulations to ensure you’re getting the best results possible.
Thank you for trusting Loshen & Crem with your skincare journey. We’re here to support you with expertise, care, and a commitment to helping you achieve safe, beautiful results.
The care behind your order
A few helpful details, before your next delivery.
Track your orderDelivery
For delivery in Canada: Standard is $25 CAD below $149 CAD. Priority is $30 CAD below $249 CAD and free from $249 CAD on eligible orders. Adding an item excluded from free Priority removes free Priority for the entire order.
This selected item excludes the entire order from free Priority shipping in Canada. Standard is $25 CAD below $149 CAD and free from $149 CAD. A paid Priority upgrade is $30 CAD where available, including orders of $249 CAD or more.
Thresholds apply after discounts, before taxes and shipping. Product, ground-shipping and destination restrictions may apply. Available services and final charges appear at checkout.
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
helps visibly reduce dark spots that appear with triggers such as sun exposure and hormonal changes.
the combination of kojic acid with an innovative peptide and an amino acid helps visibly fade dark spots and even the look of skin tone.
helps even the look of skin tone and reduce the appearance of dark spots.
offers protection from the oxidation produced by natural light and the radiation induced by technological sources (electromagnetic waves (REM), blue light (HEV)).
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover mesoestetic Melan Tran3x Concentrate at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the mesoestetic collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.
Curious about…
Our team can help you find another option suited to your skin and routine.
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