Skinbetter Science Alto Advanced Defense and Repair Serum

Daily antioxidant care for brighter, more even-looking skin

Skinbetter Science Alto Advanced Defense and Repair Serum is an antioxidant serum that helps improve the appearance of dullness, redness, uneven tone, and texture.

Combining vitamins C and E with a comprehensive antioxidant blend and patented Allyl PQQ technology, it addresses the visible effects of environmental and internal oxidative stress. Hydrating and soothing ingredients complement this daily defense, helping skin feel comfortable and look more luminous.

A thoughtful foundation for a routine centred on long-term skin health.

Benefits:

• Improves the appearance of dullness for brighter-looking skin
• Helps visibly reduce redness and uneven tone
• Refines the appearance of skin texture
• Provides antioxidant defense against environmental and internal free radicals
• Supports hydration and the skin’s moisture barrier
• Helps maintain a smoother, more supple-looking complexion

Dermatologist tested, non-comedogenic, fragrance free, paraben free, dye free, and cruelty free.

Best for:

• Dull skin lacking luminosity
• Visible redness and uneven skin tone
• Rough texture and changes in skin suppleness
• Those seeking daily antioxidant care alongside sun protection

How it works:

Alto Advanced combines two complementary approaches to antioxidant defense.

Environmental defense: Vitamins C and E work alongside 17 additional antioxidants to help neutralize free radicals associated with environmental exposure.

Internal defense: Patented Allyl PQQ technology targets free radicals generated through the body’s natural processes and supports the skin’s renewal mechanisms.

Together with moisturizing and soothing ingredients, this combination helps improve visible skin quality while supporting everyday comfort.

Clinical study:

Alto Advanced Defense and Repair Serum was evaluated in a physician-led clinical trial involving 39 participants using the serum twice daily for 12 weeks.

Skinbetter Science presents unretouched clinical photographs at four, eight, and twelve weeks. These illustrate changes over time; individual results vary. 

How to use:

1. Apply morning and evening after cleansing.
2. Smooth a thin layer over clean, dry skin on the face, neck, and décolleté.
3. Follow with the next steps in your routine and a moisturizer suited to your skin.
4. Finish your morning routine with sun protection.

Avoid contact with the eyes. If contact occurs, rinse thoroughly with water. Discontinue use if irritation or a rash develops. For external use only; keep out of reach of children.

Loshen & Crem’s recommendation:

We recommend Alto Advanced when your skin looks dull or uneven and you want to make antioxidant care a consistent part of your routine.

Begin with a gentle cleanse, apply your serum, and follow with a barrier-supporting moisturizer as needed. Keep sunscreen close at hand for the morning step. The aim is a routine that supports your skin every day and feels easy to return to.

Ingredients:

• Allyl PQQ — Pyrroloquinoline Quinone Allyl Ester: Patented antioxidant technology that helps neutralize internally generated free radicals and supports the skin’s renewal processes.
• Vitamin C — Tetrahexyldecyl Ascorbate — & Vitamin E: Complementary antioxidants that help defend against free radicals associated with environmental exposure.
• Botanical Antioxidant Blend: Green tea, grape seed, turmeric, cocoa, olive, and acai extracts contribute antioxidant support.
• Superoxide Dismutase, Ergothioneine & Coenzyme Q10: Additional antioxidants that broaden the formula’s defense.
• Niacinamide & Hydrolyzed Sodium Hyaluronate: Help maintain moisture for more comfortable, supple-feeling skin.
• Ceramides NP, AP & EOP: Support moisturization and the skin’s protective barrier.
• Bisabolol & Ginger Root Extract: A soothing combination that helps reduce the appearance of redness.
• Licorice Root Extract: Helps brighten the appearance of uneven skin tone.

Full ingredient list:

Aqua/Water/Eau, Butylene Glycol, Propanediol, Ethylhexyl Olivate, Cetearyl Alcohol, Chlorogenic Acids, Niacinamide, Lauryl Lactate, Dimethyl Isosorbide, Pyrroloquinoline Quinone Allyl Ester, Hydrolyzed Sodium Hyaluronate, Glycyrrhiza Glabra Root Extract / Licorice Root Extract, Tetrahexyldecyl Ascorbate, Ergothioneine, Taraxacum Officinale Rhizome / Root Extract – Dandelion Rhizome/Root Extract, Arabidopsis Thaliana Extract, Carnosine, Camellia Sinensis Leaf Extract, Vitis Vinifera Seed Extract / Grape Seed Extract, Theobroma Cacao Seed Extract / Cocoa Seed Extract, Curcuma Longa Root Extract / Turmeric Root Extract, Olea Europaea Fruit Extract / Olive Fruit Extract, Euterpe Oleracea Fruit Extract, Palmitoyl Tripeptide-1, Buddleja Officinalis Flower Extract, Coffea Arabica Seed Extract / Coffee Seed Extract, Crocus Sativus Callus Extract, Superoxide Dismutase, Ubiquinone, Plankton Extract, Micrococcus Lysate, Arginine, Zingiber Officinale Root Extract / Ginger Root Extract, Ceramide NP, Ceramide AP, Ceramide EOP, Linoleic Acid, Linolenic Acid, Ascorbic Acid, Bisabolol, Tocopherol, Tocopheryl Acetate, Cholesterol, Phytosphingosine, Jojoba Esters, Sodium PCA, Methyl Gluceth-20, Glycerin, Helianthus Annuus Seed Cera / Sunflower Seed Wax, Acacia Decurrens Flower Cera / Acacia Decurrens Flower Wax, Lecithin, Sodium Lauroyl Lactylate, Dicetyl Phosphate, Propanediol Dicaprylate / Caprate, Polyglycerin-3, Ceteth-20 Phosphate, Diisostearyl Malate, Xanthan Gum, Steareth-2, Acacia Senegal Gum, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Carbomer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Maltodextrin, Ricinoleth-40, Sodium Hydroxide, Citric Acid, Sodium Phytate, Ethylhexylglycerin, Phenoxyethanol, Ethylhexyl Palmitate, Alcohol, Lactic Acid, Pentylene Glycol, Sorbitan Isostearate, Tribehenin.

Please refer to your product packaging for the most current ingredient list.

Frequently asked questions:

Is Alto Advanced a vitamin C serum?

It contains vitamin C in the form of Tetrahexyldecyl Ascorbate, alongside vitamin E, botanical antioxidants, and Allyl PQQ. Vitamin C is one part of its broader antioxidant formula.

What is the difference between Alto Defense Serum and Alto Advanced?

The original Alto Defense Serum focuses on environmental antioxidant protection. Alto Advanced adds technology targeting internal oxidative stress, extending its approach to the visible effects of both internal and environmental stressors. Skinbetter Science’s comparison

Should I use it in the morning or at night?

The manufacturer recommends both. Apply after cleansing and before moisturizer, with sunscreen as the final morning step.

Does Alto Advanced replace sunscreen?

No. Antioxidant care complements sunscreen. Continue using daily sun protection while using this serum.

Do I still need a moisturizer?

Alto Advanced contains moisturizing ingredients, but dry skin may need additional replenishment. Follow with a moisturizer that suits your skin’s comfort and hydration needs.

Is a yellow or golden colour normal?

Skinbetter Science describes a colour range from yellow-beige to golden yellow, influenced by the formula’s naturally coloured antioxidant ingredients. It contains no artificial dyes.