Your routine
GlyMed PlusComfort Cream with Aloe Vera
Why it fits
A light yet deeply nourishing moisturizer designed to hydrate, soothe and protect dry, reactive or sensitized-feeling skin.
GlyMed Plus Bio Renewal Serum
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Explore La Crem rewardsGlyMed Plus Bio Renewal Serum is a powerful, peptide-rich serum designed to refine skin texture and revitalize dull or mature skin.
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Boutique details
Your Edmonton boutique.
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Standard free $149 CAD+ · Priority free $249 CAD+ on eligible orders
Standard free $149 CAD+ · Priority upgrade $30 CAD
This item excludes the entire order from free Priority, including orders of $249 CAD or more. The paid upgrade is offered where available.
Delivery details
For delivery in Canada: Standard is $25 CAD below $149 CAD. Priority is $30 CAD below $249 CAD and free from $249 CAD on eligible orders. Adding an item excluded from free Priority removes free Priority for the entire order.
This selected item excludes the entire order from free Priority shipping in Canada. Standard is $25 CAD below $149 CAD and free from $149 CAD. A paid Priority upgrade is $30 CAD where available, including orders of $249 CAD or more.
Thresholds apply after discounts, before taxes and shipping. Product, ground-shipping and destination restrictions may apply. Available services and final charges appear at checkout.
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GlyMed Plus
Bio Renewal Serum
Your ritual begins with the right choice.
$145.00 CAD
Taxes calculated at checkout.
The skincare focus
GlyMed Plus Bio Renewal Serum
GlyMed Plus Bio Renewal Serum is a powerful, peptide-rich serum designed to refine skin texture and revitalize dull or mature skin.
Explore our ingredient glossaryGlyMed Plus
The formula, explained.
The ingredients behind this formula—and what they bring to your skin.
Hexanoyl Dipeptide-3 Norleucine Acetate
Supports the skin's natural exfoliation process to improve texture and tone.
Palmitoyl Tripeptide-1
A peptide that helps reduce the look of wrinkles and improve the look of firmness.
Palmitoyl Tetrapeptide-7
A soothing peptide that promotes a smoother, firmer-looking complexion.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Pairs beautifully.
Explore another step in your face-care routine.
Your routine
GlyMed PlusMega Cream Cleanser
Why it fits
GlyMed Plus Mega Cream Cleanser is an ultra-gentle cream cleanser that effectively dissolves makeup and oil, providing a deep, yet soothing and hydrating cleanse. It is designed to be both thorough and gentle, ensuring that the skin is left clean, soft, and moisturized.
Worth knowing
The finer details.
A closer look at your skin, your routine and what goes into the formula.
GlyMed Plus Bio Renewal Serum
GlyMed Plus Bio Renewal Serum is a powerful, peptide-rich serum designed to refine skin texture and revitalize dull or mature skin. This luxurious gel serum is formulated with a blend of multi-functional peptides that support the skin's natural exfoliation, remove dull surface cells and restore the look of firmness. The result is smoother, hydrated, and more youthful-looking skin with a radiant glow. The serum targets the look of fine lines, wrinkles and uneven pigmentation, delivering a vibrant, rejuvenated complexion with regular use.
Benefits
- Renewed look: Supports the skin's natural exfoliation to create fresher, smoother skin.
- Denser-looking skin: Helps skin look denser and improves the look of elasticity and firmness.
- Refines Texture: Gently exfoliates to improve skin texture and minimize the appearance of pores.
- Smooths Fine Lines and Wrinkles: Reduces the appearance of wrinkles for a more youthful complexion.
- Brightens Pigmentation: Helps fade dark spots and even skin tone for a glowing, vibrant appearance.
- Boosts Hydration: Provides deep hydration to leave the skin feeling soft, plump, and moisturized.
How to use
- After cleansing and toning, apply one pump of Bio Renewal Serum to your face, neck, and chest in the evening.
- Gently massage the serum into your skin until fully absorbed.
- Follow with your favorite moisturizer.
- In the morning, always apply SPF after using the serum to protect your skin.
Full Ingredient List
Ingredients (INCI): Water, Acetyl Hexapeptide-8, Glycerin, Polysorbate 20, Pentylene Glycol, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Copper Tripeptide-1, Hexanoyl Dipeptide-3 Norleucine Acetate, Panthenol, Glycine, Sorbitol, Dimethyl Mea, Hydrolyzed Soy Protein, Propanediol, Butylene Glycol, Mucor Miehei Extract, Camellia Sinensis (Green Tea) Leaf Extract, Vitis Vinifera (Grape) Seed Extract, Olea Europaea (Olive) Leaf Extract, Carica Papaya Fruit Extract, Citrus Limon (Lemon) Peel Oil, Moringa Oleifera Seed Oil, Vitis Vinifera (Grape) Seed Oil, Citrus Aurantifolia (Lime) Peel Oil, Tocopherol, Tetrahexyldecyl Ascorbate, Lecithin, Carbomer, Caprylyl Glycol, Hexylene Glycol, Phenoxyethanol, Ethylhexylglycerin, Sodium Hydroxide, Mica, Titanium Dioxide, Blue 1, Yellow 5.
Shipping & returns
For delivery and return information, view our policy.
GlyMed Plus Bio Renewal Serum is a powerful, peptide-rich serum designed to refine skin texture and revitalize dull or mature skin. This luxurious gel serum is formulated with a blend of multi-functional peptides that support the skin's natural exfoliation, remove dull surface cells and restore the look of firmness. The result is smoother, hydrated, and more youthful-looking skin with a radiant glow. The serum targets the look of fine lines, wrinkles and uneven pigmentation, delivering a vibrant, rejuvenated complexion with regular use.
Benefits:
- Renewed look: Supports the skin's natural exfoliation to create fresher, smoother skin.
- Denser-looking skin: Helps skin look denser and improves the look of elasticity and firmness.
- Refines Texture: Gently exfoliates to improve skin texture and minimize the appearance of pores.
- Smooths Fine Lines and Wrinkles: Reduces the appearance of wrinkles for a more youthful complexion.
- Brightens Pigmentation: Helps fade dark spots and even skin tone for a glowing, vibrant appearance.
- Boosts Hydration: Provides deep hydration to leave the skin feeling soft, plump, and moisturized.
How to Use:
- After cleansing and toning, apply one pump of Bio Renewal Serum to your face, neck, and chest in the evening.
- Gently massage the serum into your skin until fully absorbed.
- Follow with your favorite moisturizer.
- In the morning, always apply SPF after using the serum to protect your skin.
Ingredients:
- Hexanoyl Dipeptide-3 Norleucine Acetate: Supports the skin's natural exfoliation process to improve texture and tone.
- Palmitoyl Tripeptide-1: A peptide that helps reduce the look of wrinkles and improve the look of firmness.
- Palmitoyl Tetrapeptide-7: A soothing peptide that promotes a smoother, firmer-looking complexion.
- Acetyl Hexapeptide-8: Helps reduce the look of expression lines and fine lines.
- Copper Tripeptide-1: A peptide that helps skin look firmer and rejuvenated.
- Green Tea Extract: Calms and soothes the skin while providing antioxidant protection.
- Proprietary Fruit Blend (Cranberry, Papaya, and Pineapple): Active fruit enzymes that offer gentle exfoliation, unclog pores, and brighten the skin.
Ingredients (INCI): Water, Acetyl Hexapeptide-8, Glycerin, Polysorbate 20, Pentylene Glycol, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Copper Tripeptide-1, Hexanoyl Dipeptide-3 Norleucine Acetate, Panthenol, Glycine, Sorbitol, Dimethyl Mea, Hydrolyzed Soy Protein, Propanediol, Butylene Glycol, Mucor Miehei Extract, Camellia Sinensis (Green Tea) Leaf Extract, Vitis Vinifera (Grape) Seed Extract, Olea Europaea (Olive) Leaf Extract, Carica Papaya Fruit Extract, Citrus Limon (Lemon) Peel Oil, Moringa Oleifera Seed Oil, Vitis Vinifera (Grape) Seed Oil, Citrus Aurantifolia (Lime) Peel Oil, Tocopherol, Tetrahexyldecyl Ascorbate, Lecithin, Carbomer, Caprylyl Glycol, Hexylene Glycol, Phenoxyethanol, Ethylhexylglycerin, Sodium Hydroxide, Mica, Titanium Dioxide, Blue 1, Yellow 5.
The care behind your order
From our boutique.
To your door.
A few helpful details, before your next delivery.
Track your orderDelivery
A good thing, on its way.
Delivery details
For delivery in Canada: Standard is $25 CAD below $149 CAD. Priority is $30 CAD below $249 CAD and free from $249 CAD on eligible orders. Adding an item excluded from free Priority removes free Priority for the entire order.
This selected item excludes the entire order from free Priority shipping in Canada. Standard is $25 CAD below $149 CAD and free from $149 CAD. A paid Priority upgrade is $30 CAD where available, including orders of $249 CAD or more.
Thresholds apply after discounts, before taxes and shipping. Product, ground-shipping and destination restrictions may apply. Available services and final charges appear at checkout.
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Collect in Edmonton.
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Here after checkout, too.
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Hexanoyl Dipeptide-3 Norleucine Acetate
Supports the skin's natural exfoliation process to improve texture and tone.
Palmitoyl Tripeptide-1
A peptide that helps reduce the look of wrinkles and improve the look of firmness.
Palmitoyl Tetrapeptide-7
A soothing peptide that promotes a smoother, firmer-looking complexion.
Acetyl Hexapeptide-8
Helps reduce the look of expression lines and fine lines.
Copper Tripeptide-1
A peptide that helps skin look firmer and rejuvenated.
Green Tea Extract
Calms and soothes the skin while providing antioxidant protection.
Proprietary Fruit Blend (Cranberry, Papaya, and Pineapple)
Active fruit enzymes that offer gentle exfoliation, unclog pores, and brighten the skin.
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Your skin.
Our attention.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.Personal guidance, in Edmonton or online.
The care behind your care
A place in your routine.
A team in your corner.
From your first question to your next replenishment, there’s a real person here to help.
01 Make sense of what you already use
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our team02 Get to know your skin
Take our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting point03 Keep the conversation going
A question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Explore GlyMed Plus.
Find your place to begin.
Discover GlyMed Plus Bio Renewal Serum at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the GlyMed Plus collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
Your ritual, beautifully noted.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.