Skip to content
Schedule your appointment

Cart

Your cart is empty

Active Serum

Sale price$204.00 CAD

Tax excluded. Shipping calculated at checkout


GWP IS Clinical Brightening Serum & Brightening Complex (With purchases of two full size serums) | GWP | LOSHEN & CREM

Clarifying, Brightening, Smoothing

iS Clinical Active Serum is a best-seller for a reason: this concentrated botanical formula delivers fast, visible results. Loved for its ability to refine texture, brighten uneven tone, and support clearer-looking skin, it’s a go-to treatment for those navigating congestion, dullness, or early signs of skin maturity.

Formulated with a blend of naturally derived exfoliants and brightening actives, Active Serum helps soften the appearance of fine lines, smooth rough texture, and minimize the look of imperfections. Its cooling, tingling sensation is a signature of its performance—an immediate indicator of the ingredients at work on the skin’s surface.

Lightweight and fast-absorbing, this serum layers seamlessly into any evening skincare routine, leaving the skin refreshed, smooth, and more radiant over time.

Benefits:
  • Helps soften the appearance of fine lines and textural irregularities
  • Visibly improves uneven skin tone and post-blemish marks
  • Promotes clearer, more refined-looking pores
  • Provides both instant and long-term visible results
  • Supports brighter, smoother, more balanced-looking skin

Looking for targeted care around the eyes? Explore iS Clinical C-Eye Serum for the delicate under-eye area.

How to use:

For optimal results, use in the evening only, as this formula is exceptionally active.

After cleansing, dispense half a pipette into the palm of your hand. Using your fingertips, gently smooth the serum over your face and neck. A light, cooling tingle is normal and reflects the potency of the botanical actives working at the skin’s surface.

For additional hydration, layer with iS Clinical Hydra-Cool Serum.

Ingredients:
  • Arbutin & Mushroom Extract – Help visibly brighten and unify the look of uneven skin tone.
  • White Willow Bark Extract – A natural beta-hydroxy derivative that gently exfoliates and helps decongest pores.
  • Bilberry Extract – Rich in antioxidants, offering mild exfoliation and comfort to the skin.
  • Sugar Cane Extract – A natural source of glycolic acid to refine texture and promote renewed radiance.

Water/Aqua/Eau, Glycerin, Butylene Glycol, Alcohol Denat., Saccharum Officinarum (Sugarcane) Extract [Extrait de canne à sucre], Vaccinium Myrtillus Fruit/Leaf Extract, Triethanolamine, Salix Alba (Willow) Bark Extract, Glyceryl Polyacrylate, Arbutin, Polyporus Umbellatus (Mushroom) Extract, Menthol, Phenoxyethanol

Free Express Shipping with orders over $199

Available at our Edmonton Boutique

Ship to Canada only

In stock
Size:

Pickup available at Loshen & Crem

Usually ready in 24 hours

Active Serum | Serum - Clarifying | LOSHEN & CREM

Active Serum

30 ml

Loshen & Crem

Pickup available, usually ready in 24 hours

5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada

+17807229086
Active Serum | Serum - Clarifying | LOSHEN & CREM
Active Serum Sale price$204.00 CAD
  • 5 stars: 49 (91%)
  • 4 stars: 5 (9%)
  • 3 stars: 0 (0%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
M
Monse
Magic in a Bottle!

I absolutely love this serum! Not only does it smooth fine lines and even out my skin tone, but it’s also incredible for breakouts. A tiny drop on a pimple and it’s gone almost overnight! It gives my skin an instant boost of brightness, and I love how soft, hydrated, and smooth it leaves my face. It’s definitely a staple in my skincare rotation, perfect for those days when my skin needs a little extra love. Highly recommend!

H
Hayley
Works wonders on acne!

I use this serum more like a spot treatment on active breakouts and it’s wonderful. It’s very cooling and intense but the results always show the next day. I also love that it has brighteners to help with the post inflammatory erythema after a breakout. Will keep in my cupboard at all times.

D
Diana
I cannot live without this

If they discontinue this I will not survive

S
Sandra

ACTIVE SERUM

K
Kr
Love it, the best serum

Love it, the best serum

K
Kr
amazing

my fav serum alongside pro health one

K
Kr
SSOOOOO GOOD

thank you

K
Kr
Good for any break outs you might have

makes my face glow THE most out of all the expensive and medical grade skincare products I have. Stinging a little bit but you get used to it, works with any pimples you might have, polishes your face. my third bottle already LOVE it.

N
Neha
Very good serum

I have used 3 serums so far from IS Clinical - pro health serum, super serum and active serum and all have worked like magic on my skin.

D
D.P.

I been finding since using this product faithfully my skin has never looked better. Highly recommend this product.

D
Darcey

Fast shipping. Active serum is great!

D
Darcey

Excellent service

D
Dariya
perfect!

perfect!

A
Amanda
MUST HAVE!

This product has honestly changed my skin. I have really sensitive, acne prone skin and this has been a game changer!! My breakouts are few and far between and my complexion has never been so even. Thankful for the best skin of my life 🫶🏼

V
Valeria
Magic in the Bottle l

Love this serum, it really helps to get rid of acne scars or to actually prevent spots from getting bigger. The skin looks smoother after using it. This is my second bottle and will definitely be repurchasing.

M
Maddie
Keeps my Acne at Bay

This stuff is fantastic. I really notice a difference if I skip a day of using it. Keeps my acne at bay… will 100% continue to repurchase!

S
Simone
Game Changer

This serum has transformed my skin! It has helped control my hormonal cystic acne while minimizing fine lines, and ultimately create a glass skin look.

k
katie
#1 product!

Would buy this over and over! Highly recommend. Super gentle

B
Brittany
Powerful product

Wonderful serum! It lives up to its claims and reduces breakouts very quickly compared to all other serums I've tried. Moisturizing well after application is key as it is quite drying.

K
Kevin
Very impressed with this serum

My second purchase of the iS Active Serum and this time I got the 30 ml size. I've been using the active serum pretty much everyday and sometimes twice a day for over a month now and its made a difference in crows feet around my eyes and its even out my skin tone, which I wasn't looking to solve as something I noticed but now that I see how even my skin looks, I'm pretty impressed and this serum is now part of my daily routine. I love that I can still feel the slight tingle on my skin when I put it on. Because this serum is thinner, I usually layer it with another serum. Either way, I'd miss that daily tingle, the light smell and and the end results are really visible/lasting. For me, this Active serum clearly works. - Honest review from a mid 50's guy.

K
Khuraman
Hit and miss

This is not a bad serum at all but I am struggling to determine if this is actually helping. I first started using it 3 years ago prior to discovering BR and the complete iribiol and dermopurifiante creme. At that time my chin and my jawline was full of hormonal bumps and this did nothing to me. I stopped it and tried it again when my husband needed something for his pimples (btw, works wonders for him in one night gets rid of EVERYTHING on his skin!) and I found it being clarifying, but again not getting rid of any active breakouts (I only have them now around my periods). So it is good but not as good as BR. And for pregnant women be careful, this contains arbutin - a derivative of hydroquinone that is not safe for pregnancy.

K
Kevin
Excellent

Wow, this is a strong serum and was immediately impressed with it and you do feel the effects within a few minutes. My only complaint would be that the "how to use" info on the site says 3-4 drops of serum. I personally found the serum to be thin and if I am not mistaken, being botanically sourced, the serum might have been in an alcohol base. I found that putting drops in my palm caused the base to evaporate and I probably needed closer to 10 drops. I think I was expecting a thicker consistency and found the thinner consistency harder to apply or spread around BUT I did find it effective too and I would purchase again and will try a few other of the iS Clinical products. - Honest review from a mid 50's guy.

a
aldijana
Amazing

I love this serum. It has a nice cooling and tingly feeling. Keeps my skin clear and I find it to give a nice glow as well

T
T.
Acne prone solution

I’ve been struggling with bad acne the best few months. This was recommended by my aesthetician and it works wonders

S
Steven
Amazing

This stuff is magic. Highly recommend if you have acne you want to get rid of.

K
Kristina
It’s super good! I’m amazed right now!!

5 stars !

A
Adi
Incredible Product!

My skin is brighter, complexion is even, skin smooth, acne cleared…all within days! This product honestly feels like a miracle.

H
Heidi

ACTIVE SERUM

A
Anonymous
Love it

Great serum, brightens my skin!

J
Jessa
Staple

been a staple in my routine for years! use 1-2 times per week and no breakouts :)

V
Vanda
Active Serum

Writing a second review as continuing to use this product for over 6 months now and I must say it is wonderful for using as a spot treatment for acne.
Clears acne very well