Calecim® Professional Serum

Concentrated PTT-6® Serum for Post-Procedure Skin, Firmness & Visible Skin Renewal

CALECIM® Professional Serum is an advanced, lightweight serum formulated with the highest concentration of PTT-6® in the CALECIM skincare range. Originally developed for use alongside professional aesthetic treatments, it is designed for mature, sensitized and post-procedure skin, as well as anyone looking to improve the visible quality, firmness and resilience of their complexion.

At the centre of the formula is PTT-6®, CALECIM’s proprietary complex of bioactive signalling proteins, including growth factors, cytokines and structural proteins. The fast-absorbing, fragrance-free formula helps skin appear smoother, firmer, more even and refreshed while providing lightweight hydration without a heavy or occlusive finish.

Professional Serum can be incorporated into a daily skincare routine or used as part of a professionally guided post-treatment protocol following procedures such as microneedling, RF microneedling, laser resurfacing and chemical peels.

Recommended For

• Mature skin and visible signs of skin aging
• Fine lines and wrinkles
• Loss of visible firmness and elasticity
• Uneven or rough-looking skin texture
• Dull or fatigued-looking skin
• Thin or sensitized-feeling skin
• Post-procedure skincare
• Skin undergoing professional microneedling, RF microneedling, laser or resurfacing treatments
• Clients looking for an advanced growth factor and bioactive protein serum

Professional Serum is suitable for all skin types. CALECIM does not recommend applying it over active inflammatory acne or open acne lesions.

Benefits

• Helps soften the visible appearance of fine lines and wrinkles
• Promotes firmer, smoother and more resilient-looking skin
• Helps refine the appearance of uneven or rough skin texture
• Supports a more even, refreshed-looking complexion
• Provides lightweight hydration with hyaluronic acid
• Helps improve the appearance of skin experiencing temporary post-treatment sensitivity
• Complements professional aesthetic procedures and post-procedure skincare protocols
• Layers easily beneath other serums, moisturizers and sunscreen
• Fragrance-free and suitable for sensitive skin

What Makes CALECIM Professional Serum Different?

Professional Serum contains the highest concentration of PTT-6® within CALECIM’s skincare collection, making it the brand's most concentrated option for clients looking for targeted support for visible skin renewal and post-procedure care.

Unlike a conventional hydrating or peptide serum, CALECIM Professional Serum is centred around bioactive cell-signalling proteins.

What Is PTT-6®?

PTT-6® is CALECIM’s proprietary technology developed through regenerative medicine research using ethically sourced umbilical cord lining stem cells.

The complex contains a broad spectrum of naturally occurring bioactive signalling molecules, including growth factors, cytokines and proteins involved in cellular communication, alongside components such as:

• Glycoproteins
• Soluble collagen
• Albumin
• Fibronectin
• Hyaluronic acid

The finished Professional Serum does not contain stem cells.

In skincare, PTT-6® is used to support the appearance of healthier, smoother, firmer and more resilient skin, particularly when the skin is showing visible signs of aging or temporary stress following an aesthetic procedure.

Professional Serum & Post-Procedure Skincare

CALECIM Professional Serum was originally developed for use by physicians and aesthetic practitioners following professional treatments.

It is commonly incorporated into protocols involving:

• Microneedling
• RF microneedling
• Laser resurfacing
• Chemical peels
• Dermabrasion
• Other professionally administered resurfacing treatments

These procedures temporarily place the skin into a heightened state of renewal. Professional Serum is designed to complement this period with concentrated PTT-6® while helping the skin appear comfortable, hydrated and healthy throughout the visible recovery process.

The appropriate timing for applying skincare after a procedure depends on the treatment performed. Always follow the post-care instructions provided by your treating physician, facialist or skincare professional.

How to Use

As a Daily Serum

Apply approximately one pipette to freshly cleansed skin.

Gently distribute over the face and allow the serum to absorb before applying additional serums, moisturizer or facial oil.

During the day, finish with broad-spectrum sunscreen.

After a Professional Treatment

Professional Serum may be incorporated into a post-procedure protocol following treatments such as microneedling, RF microneedling, laser resurfacing or chemical peels.

Depending on the treatment, your practitioner may apply the serum professionally and recommend continuing with it at home during the days following your appointment.

Always follow the specific post-treatment instructions provided by your treating professional.

Loshen & Crem's Recommendation

We think of CALECIM Professional Serum differently from an everyday hydrating serum.

This is the serum we reach for when the skin needs something more focused: after an advanced treatment, when the complexion is looking particularly depleted, or when mature skin is beginning to show changes in firmness, texture and overall skin quality.

Its exceptionally light texture is also one of its strengths. You receive a highly concentrated treatment without adding another rich or heavy layer to the routine, making it easy to combine with the skincare you already use.

For clients undergoing a series of advanced treatments, we especially like Professional Serum as part of a thoughtfully planned homecare routine before and after appointments.

CALECIM Professional Serum vs. Recovery Night Complex

Both formulas contain CALECIM's PTT-6® technology, but we recommend them differently.

Professional Serum is the more concentrated, lightweight option. It contains the highest concentration of PTT-6® in the CALECIM skincare range and is particularly well suited to professional protocols, post-procedure routines and clients wanting an intensive treatment serum.

Recovery Night Complex has a more protective gel-like texture that creates a light film over the skin. We prefer it as an evening product when additional comfort and hydration are desired.

For certain post-treatment routines, the two can also be layered together: Professional Serum first, followed by Recovery Night Complex, when recommended by your skincare professional.

Ingredients

• PTT-6®: CALECIM's proprietary bioactive protein complex containing glycoproteins, soluble collagen, albumin, fibronectin, hyaluronic acid and naturally occurring signalling molecules. It is the signature technology behind the CALECIM Professional skincare collection.
• Hyaluronic Acid: A naturally occurring humectant that helps attract and retain moisture, supporting a hydrated, supple and smoother-looking complexion.

Full Ingredient List — INCI

Aqua (Water), Hyaluronic Acid, Glycoproteins, 1,2-Hexanediol, Soluble Collagens, Albumin, Fibronectins.

Ingredient lists may be updated by the manufacturer from time to time. For the most current information, please refer to the ingredient list printed on your product packaging.

If you have an allergy or known ingredient sensitivity and would like assistance verifying the current formula before purchasing, contact the Loshen & Crem team at info@loshen.ca.

Frequently Asked Questions

What is CALECIM Professional Serum?

CALECIM Professional Serum is a concentrated PTT-6® skincare serum designed for mature, sensitized and post-procedure skin. It contains the highest concentration of PTT-6® in CALECIM's skincare range and can be incorporated into both daily homecare and professionally guided post-treatment routines.

Is CALECIM Professional Serum a growth factor serum?

CALECIM Professional Serum contains PTT-6®, a proprietary complex containing naturally occurring growth factors, cytokines and other bioactive signalling proteins developed from ethically sourced umbilical cord lining stem cell research.

The finished serum does not contain stem cells.

Can I use CALECIM Professional Serum after microneedling?

Yes. Professional Serum was originally developed for professional aesthetic protocols and is commonly incorporated into skincare following microneedling and RF microneedling.

The appropriate time to apply the serum depends on the treatment performed, so follow the post-care protocol provided by your treatment professional.

Can Professional Serum be used after laser treatments or chemical peels?

CALECIM Professional Serum is commonly used as part of professionally directed skincare following resurfacing procedures including certain laser treatments and chemical peels.

Because post-procedure requirements vary considerably, follow the instructions provided by the professional who performed your treatment.

Can I use CALECIM Professional Serum every day?

Yes. Professional Serum can also be used independently of professional treatments as part of a daily skincare routine.

Apply approximately one pipette after cleansing and before moisturizer.

Can I use Professional Serum with retinol or vitamin C?

Professional Serum can generally be layered with ingredients including vitamin C, retinoids, niacinamide, peptides and other serums.

If you have recently undergone an aesthetic treatment, your usual active ingredients may need to be temporarily paused. Follow the post-treatment instructions provided by your skincare professional.

Is CALECIM Professional Serum suitable for sensitive skin?

CALECIM describes Professional Serum as suitable for sensitive skin. Its lightweight formula is fragrance-free and was originally developed with post-procedure skin in mind.

Clients with highly reactive skin, known allergies or an active skin condition should consult their healthcare or skincare professional before introducing a new product.

Can Professional Serum be used on acne-prone skin?

Professional Serum is not intended to treat acne and CALECIM does not recommend using it directly over active inflammatory acne or open acne pustules.

It may be incorporated into professionally guided routines focused on the visible appearance of post-acne marks or textural irregularities once active breakouts have settled.

What is the difference between CALECIM Professional Serum and Multi-Action Cream?

Professional Serum is CALECIM's more concentrated PTT-6® treatment and is particularly well suited to targeted routines and post-procedure skincare.

Multi-Action Cream combines PTT-6® technology with the comfort and emollience expected from a daily moisturizer and is better suited to clients wanting ongoing daily moisturization alongside CALECIM technology.

The two can also be layered, with Professional Serum applied first.

Why is CALECIM Professional Serum pink?

The colour of Professional Serum can naturally range from yellow-orange to pink or deeper pink. CALECIM explains that the formula contains a pH indicator and that slight variations between batches may influence its colour.

This variation is normal.

Where to Buy CALECIM Professional Serum in Canada

CALECIM Professional Serum is available in Canada through Loshen & Crem, an independent skincare boutique and facial studio located in Edmonton, Alberta.

Shop Professional Serum online for Canadian delivery or choose local pickup from our Edmonton boutique. Our team of facialists and skincare professionals can also help you determine how to incorporate CALECIM into your existing homecare or post-treatment routine.