


Serum Grand Millesime
Tax excluded. Shipping calculated at checkout
Free Shipping
Regular $149+
Priority $249+
Complimentary Samples
With every order
Pickup available at Loshen & Crem
Usually ready in 24 hours

Serum Grand Millesime
30 ml
Loshen & Crem
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
Need a little guidance?
Book a Virtual Skin Consultation
Personalized product guidance with a Loshen & Crem facialist, wherever you are.
A finishing serum for radiance, hydration, and timeless skin.
A true elixir of youth, Sérum Grand Millésime is the finishing touch to your skincare routine, designed to brighten, hydrate, and smooth the skin while reinforcing its natural defense system. This global anti-aging serum works beyond hydration, it helps revitalize tired-looking skin, bringing immediate radiance and a rested, luminous appearance.
Ideal for seasonal skin transitions or periods of fatigue, Sérum Grand Millésime infuses the skin with hydrating, antioxidant, and reconditioning actives for a visibly healthier, more youthful-looking complexion.
Skin instant:
For skin showing signs of fatigue, dehydration, or dullness. Ideal for mature skin or those looking for an instant glow boost and enhanced skin resilience.
Benefits:
- Brightens and evens out the complexion
- Smooths and tones the epidermis for a revitalized appearance
- Strengthens the skin’s natural defenses with powerful antioxidants
- Deeply hydrates while enhancing skin’s suppleness and glow
- A perfect final step in any Biologique Recherche routine
How to use:
Apply a few drops of Sérum Grand Millésime to the face, neck, and décolleté in the morning and/or evening.
- Do not apply to the eye area.
- This serum is one of the last steps in a Biologique Recherche skincare program.
- Use it as a revitalizing course at the change of seasons or during periods of fatigue for an instant boost.
Loshen & Crem’s recommendation:
Sérum Grand Millésime is the perfect finishing serum for those looking to elevate their routine with an added layer of hydration, radiance, and antioxidant protection.
Ingredients:
- Mimosa extract & hamamelis extract – Tones, brightens, and revitalizes the skin.
- Hyaluronic acid & cucumber extract – Deeply hydrates and plumps the skin.
- Silk extract & lactic acid – Refines and smooths texture while promoting a luminous glow.
- Cider vinegar & myrrh – Potent antioxidants that protect the skin from environmental damage.
- Yeast extract & niacinamide – Strengthens the skin’s natural barrier and supports regeneration.
Full ingredients list
WATER (AQUA), PROPYLENE GLYCOL, GLYCERIN, CUCUMIS SATIVUS (CUCUMBER) FRUIT EXTRACT, ACACIA SENEGAL GUM, HYDROLYZED SILK, NIACINAMIDE, MAGNESIUM CHLORIDE, MYRTUS COMMUNIS LEAF EXTRACT, ALLIUM CEPA (ONION) BULB EXTRACT, COMMIPHORA MYRRHA RESIN EXTRACT, HAMAMELIS VIRGINIANA (WITCH HAZEL) BARK/LEAF EXTRACT, HYPERICUM PERFORATUM FLOWER/LEAF/STEM EXTRACT, SOPHORA JAPONICA FLOWER EXTRACT, YEAST EXTRACT, RHIZOBIAN GUM, GLUCONOLACTONE, LACTIC ACID, SODIUM LACTATE, SALICYLIC ACID, CITRIC ACID, ALLANTOIN, SERINE, PYRIDOXINE HCL, THIAMINE HCL, VINEGAR (ACETUM), SORBITOL, CARAMEL, ALCOHOL DENAT., TEA-LACTATE, PROPANEDIOL, UREA, SODIUM BENZOATE, POTASSIUM SORBATE, SODIUM BISULFITE.
Ingredients are subject to change at the manufacturer’s discretion. For the most complete and up-to-date list, refer to the product packaging
⚠️ Important notes :
- This is a highly concentrated product; mild redness may appear upon first applications. If irritation persists, discontinue use.
- Do not use immediately after deep exfoliation treatments.
- Avoid sun exposure directly after application.
- Not suitable for children.
BR Skin Reaction Policy 📄
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
Choose options



A final gesture of care, a whisper of radiance.
La Touche Finale
In this short video, discover how to apply your Biologique Recherche Finishing Serum, a precious step in your ritual that elevates your skin to its most refined state.
With just a few drops, pressed gently into the skin, your complexion is left silky, luminous, and perfectly sealed.

