

Collagene Originel Serum
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3D REDENSIFYING FACE SERUM
Biologique Recherche Collagène Originel is an intensive anti-wrinkle and plumping serum designed for skin showing visible wrinkles, reduced density and changes in structural support.
Collagen plays an essential role in the skin's firmness and density, but not all collagen performs the same function. Different collagen types contribute to the deeper structure of the dermis as well as the connection between the dermis and epidermis.
Collagène Originel is designed to support this structural network, helping skin appear smoother, firmer and more densely plumped while visibly reducing the appearance and length of wrinkles.
With continued use, the complexion looks more supported, cushioned and refined.
Skin Instant:
Recommended for Skin Instants showing wrinkles and visible changes in density.
Particularly suited to skin experiencing:
- Established or increasingly visible wrinkles
- Loss of skin density
- Reduced plumpness
- Skin that appears thinner or less cushioned
- Changes in structural firmness
- Fine lines becoming more established
- A complexion that no longer looks as full or supported as it once did
Benefits:
- Helps visibly reduce the appearance of wrinkles
- Helps reduce the visible length of wrinkles
- Supports skin structure and density
- Promotes a firmer-looking complexion
- Helps visibly plump the skin
- Supports the dermal-epidermal junction
- Helps improve the appearance of skin mechanical resistance
- Leaves skin looking smoother, denser and more supported
What Does “3D Redensifying” Actually Mean?
This is where Collagène Originel becomes much more interesting than simply calling it a “collagen serum.”
Collagen is a structural protein, but several types of collagen exist within different layers of the skin.
Collagen types I and III contribute significantly to the density and structural support of the dermis.
Collagen types IV and VII are associated with the dermal-epidermal junction — the area connecting the deeper dermis with the epidermis above it.
This junction matters because it helps anchor and support the different layers of the skin.
As skin changes over time, this structural network can become less robust. The result may be skin that appears thinner, less dense, less plump and more visibly wrinkled.
Collagène Originel is designed around this broader understanding of skin structure.
Rather than thinking only about the surface appearance of a wrinkle, think of this serum as supporting the architecture underneath it.
Clinically Evaluated Skin Structure
In an ex-vivo study conducted by Biologique Recherche on human skin explants, a 22% increase in the dermal-epidermal junction index was observed after four applications over six days.
This measurement reflects stronger connections between the layers of the skin and supports the appearance of smoother, firmer and more youthful-looking skin.
How to Use:
After cleansing and applying your more fluid serum, apply a few drops of Collagène Originel morning and evening to the face, neck and décolleté.
Press gently into the skin using the palms of the hands until completely absorbed.
Within a Biologique Recherche routine, apply after cleansing, your appropriate Lotion P50 and lighter serums, and before your moisturizer.
Avoid contact with the eyes. For external use only.
Loshen & Crem’s Recommendation:
Collagène Originel is one of the Biologique Recherche serums we reach for when the conversation shifts from simply treating fine lines to noticing a change in the density and structure of the skin itself.
Think:
- “My skin doesn't feel as plump as it used to.”
- “My wrinkles are becoming more established.”
- “My skin seems thinner.”
- “I want my skin to look fuller and more supported.”
- “I have firmness, but what I'm really noticing is loss of density.”
That last distinction matters.
Firmness, wrinkles, elasticity and density are connected, but they are not identical concerns.
Collagène Originel is particularly interesting when wrinkles are becoming more established alongside a visible loss of plumpness and density.
Think of it as a structural and plumping serum, rather than simply another firming serum.
Collagène Originel vs. Elastine
Both target wrinkles, but they approach them differently.
Choose Elastine when your primary concern is:
- Fine lines
- Wrinkle smoothing
- Reduced elasticity
- Early changes in the flexibility of the skin
Choose Collagène Originel when the concern has progressed toward:
- More established wrinkles
- Loss of density
- Reduced plumpness
- Changes in the structural support of the skin
In the simplest terms:
- Elastine = elasticity + wrinkle smoothing
- Collagène Originel = density + structure + plumping
Depending on your Skin Instant, both may sometimes be incorporated within the same personalized routine.
Collagène Originel vs. VG Tensil
These are also very different despite both being associated with visible skin aging.
Choose VG Tensil when the primary concern is:
- Loss of tone
- Skin laxity
- Softer facial contours
- Reduced jawline definition
- A need for a tautening effect
Choose Collagène Originel when the primary concern is:
- Wrinkles
- Loss of density
- Reduced plumpness
- Skin that appears thinner or less structurally supported
Think:
- VG Tensil → firmness + tone + contour
- Collagène Originel → density + plumpness + wrinkles
Collagène Originel vs. Progeskin
This is an important comparison because both can make sense when several visible signs of skin aging begin to appear.
Collagène Originel is more specifically centred around:
- Skin structure
- Wrinkles
- Density
- Plumpness
- The dermal-epidermal junction
Progeskin takes a broader approach to the visible aging process and is designed to improve overall skin appearance, firmness, tone and plumpness.
In the simplest terms:
- Collagène Originel = structural density + wrinkles + plumping
- Progeskin = broader visible skin aging + firmness + tone + skin quality
If your biggest concern is that the skin feels thinner and established wrinkles are becoming more visible, Collagène Originel may be the more targeted choice.
If several aspects of the skin seem to be changing at once, Progeskin may make more sense.
Ingredients:
- Hydrolyzed Soy Flour: A soy-derived ingredient incorporated into the serum's targeted skin-conditioning and structural-support formula.
- Chlorella Vulgaris Extract: A microalgae-derived botanical extract used within the serum's redensifying complex.
- Hydrolyzed Collagen: A skin-conditioning ingredient that contributes to the serum's smoothing and plumping properties.
- Glycerin: A humectant that attracts water and helps maintain skin hydration.
- Mineral Salts: Included within the serum's targeted formulation to support overall skin conditioning.
- Saponins: Plant-derived compounds incorporated within the serum's active complex.
Full INCI List:
Water (Aqua), Glycerin, Methylpropanediol, Caprylyl Glycol, Xanthan Gum, Hydrolyzed Soy Flour, Chlorella Vulgaris Extract, 1,2-Hexanediol, Saponins, Hydrolyzed Collagen, Mineral Salts, Sodium Benzoate.
The lists of ingredients used in Biologique Recherche products are updated regularly. Before using a Biologique Recherche product, please refer to the ingredient list on its packaging.
If you have allergies or known ingredient sensitivities, please contact us at info@loshen.ca before purchasing. Our team will be happy to help verify the most current ingredient list for you.
Frequently Asked Questions
What is Biologique Recherche Collagène Originel?
Collagène Originel is a 3D redensifying, anti-wrinkle and plumping facial serum from Biologique Recherche. It is designed to support skin structure while helping reduce the appearance of wrinkles and improve visible firmness and density.
What does Collagène Originel do?
It helps support the structural network of the skin, visibly plump wrinkles and improve the appearance of firmness and density.
What does “redensifying” mean in skincare?
Redensifying refers to improving the appearance of skin that has begun to look thinner, less cushioned or less structurally supported. The goal is skin that appears fuller, plumper and more resilient.
Is Collagène Originel a collagen serum?
Collagène Originel is designed around the biology of collagen and skin structure. Its formula includes hydrolyzed collagen alongside other ingredients selected for its redensifying and anti-wrinkle action.
Does topical collagen replace lost collagen in the skin?
No. A topical skincare product does not simply replace the collagen naturally found deep within the dermis. Collagène Originel is formulated to support the appearance and structural quality of the skin rather than acting as a direct replacement for your natural collagen.
What is the dermal-epidermal junction?
The dermal-epidermal junction is the interface connecting the epidermis with the dermis beneath it. Collagen types IV and VII play important structural roles in this area, helping anchor and support the skin's layers.
Does Collagène Originel help wrinkles?
Yes. Biologique Recherche positions Collagène Originel as an anti-wrinkle and plumping serum for skin showing wrinkles. With continued use, wrinkles appear visibly plumped and reduced in length.
Is Collagène Originel for fine lines or deeper wrinkles?
It may be used when wrinkles are visible, but we particularly like it when lines are becoming more established and are accompanied by loss of density or plumpness.
For very early fine lines where elasticity is the greater concern, Elastine may sometimes be the more targeted choice.
What is the difference between Collagène Originel and Elastine?
Elastine focuses primarily on smoothing wrinkles and supporting elasticity. Collagène Originel focuses more specifically on wrinkles alongside loss of density, plumpness and structural support.
What is the difference between Collagène Originel and VG Tensil?
VG Tensil focuses primarily on loss of tone, firmness and facial contour definition. Collagène Originel is more specifically targeted toward wrinkles, density and plumpness.
What is the difference between Collagène Originel and Progeskin?
Collagène Originel focuses primarily on skin structure, wrinkles and density. Progeskin takes a broader approach to visible skin aging, targeting overall appearance, firmness, tone and plumpness.
Can I use Collagène Originel every day?
Yes. Biologique Recherche recommends applying a few drops morning and evening according to the needs of your Skin Instant.
When should I apply Collagène Originel?
Apply it after cleansing and your appropriate Lotion P50. If using several serums, apply lighter and more fluid serums first, followed by Collagène Originel and then your moisturizer.
Who should use Biologique Recherche Collagène Originel?
It is particularly suited to Skin Instants showing wrinkles alongside visible loss of density, plumpness or structural support.
Where can I buy Biologique Recherche Collagène Originel?
Biologique Recherche Collagène Originel is available from Loshen & Crem online and at our Edmonton, Alberta boutique.
Our skin experts can also help determine whether Collagène Originel, Elastine, VG Tensil, Progeskin or another Biologique Recherche serum is best suited to your current Skin Instant.
Biologique Recherche Skin Reaction Policy
At Loshen & Crem, we highly recommend completing a consultation with one of our skin experts before introducing a new Biologique Recherche product into your routine.
In the event of a skin reaction, Biologique Recherche may require:
- Clear photos of the reaction
- Photos of the product and lot number
- Proof of an online consultation with one of our skin experts
If you choose to purchase a Biologique Recherche product without a consultation and experience a reaction, we may be unable to provide a refund under the brand's policy.
If you are unsure whether Collagène Originel is right for your Skin Instant, our team is always available to help.
Free Express Shipping with orders over $199
Available at our Edmonton Boutique
Ship to Canada only
Pickup available at Loshen & Crem
Usually ready in 24 hours

Collagene Originel Serum
30 ml
Loshen & Crem
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
Returns & Refunds
At Loshen & Crem, we understand that sometimes, even the most carefully chosen product might not be "the one."
- Returns: You have 30 days from delivery to return any unopened and unused products in perfect condition—just as they arrived.
- Refunds: If your return reaches us within 30 days of purchase, you’ll have the choice between a refund or store credit (your preference, naturellement). After 30 days, store credit is your only option. Beyond 40 days, refunds and credits are no longer possible.
Final Sale Items
For transparency, certain items are final sale and not eligible for return or exchange:
- Products on sale
- Products marked “Final markdown” on our online store
- Gift cards
- Promotional kits and deluxe samples
- Limited-edition or seasonal item
Shipping Policy
At Loshen & Crem, we take delivering your skincare treasures très seriously. From Canada to the U.S., we’re here to ensure your beauty cabinet is always well-stocked.
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Free Shipping:
- Canada: Complimentary EXPRESS shipping on orders over $199 CAD (after discounts and before taxes).
- United States: Complimentary EXPRESS shipping on orders over $350 USD.
- During our annual sales, enjoy free EXPEDITED shipping for orders over $250 CAD (or $450 USD).
- For smaller indulgences, shipping is $27.95 CAD within Canada and $35 USD to the U.S.
P.S. We ship to P.O. Boxes via Canada Post—but not during strikes. C’est compliqué.
Processing Time:
We aim to dispatch your order within 2 business days, though peak sales and payment verifications may require a touch more patience.
Please note that if you make any changes with the courier after the dispatch, our carrier will charge a $32 fee. In addition, we will have to withdraw 800 points from your La Crème Points account. We appreciate your understanding.
Our processing time starts from the moment your order is successfully submitted and may take up to 2 business days to dispatch your order. However, please be aware that processing and handling time may be extended during peak sale periods. Before we can ship your order, we may need to hold your order for payment verification and confirm your details with your card issuer.
We will do our very best to minimize delays.
Shipping Rates & Delivery Times
Estimated Delivery Times (Canada):
- British Columbia & Alberta: 1–2 business days
- Manitoba & Saskatchewan: 1–2 business days
- Quebec & Ontario: 1–2 business days
- Atlantic Provinces: 1–3 business days
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United States: Delivery times vary by region:
- Zone 1: Eastern States – 3–4 business days
- Zone 2: Central States – 4–5 business days
- Zone 3: Western States – 5 business days
Remote areas may experience longer shipping times.Please Note: Shipping windows are estimates and not guarantees. Delays may occur due to weather, traffic, or additional verification processes.
Shipping Address Details
For a smooth delivery, please provide all relevant information, including buzzer codes, directional suffixes (North, South, etc.), or special instructions.
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Address Changes: Once your package has left our warehouse, address updates cannot be made. If you need to make changes before dispatch, email us at info@loshen.ca with your order details.
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Carrier Fees: Any changes made with the courier after dispatch will incur a $32 CAD fee, and the Free Express Shipping option will be deducted from your La Crème Points account.
Tracking Your Order
All shipments include tracking information, so you can follow your package from our warehouse to your door. A confirmation email with your tracking number will be sent once your order is dispatched.
Damaged or Lost Packages
- Damaged Parcels: If your order arrives damaged, please contact us at info@loshen.ca with photos and details. We’ll work to resolve the issue promptly.
- Lost or Stolen Packages: If your package is marked "delivered" but hasn’t arrived, please contact the carrier directly to file a claim.
Tips to Avoid Lost or Stolen Packages:
- Opt for a signature upon receipt (required for orders over $350 CAD).
- Have your package delivered to your workplace.
- If you’re not home on the expected delivery date, ask a neighbor to receive your package.
Unclaimed Parcels
If your package is returned to us unclaimed, we’ll issue a refund minus a $29.95 CAD return shipping fee.
Free Samples
We believe every order deserves a little extra care! Expect 1–3 complimentary samples selected by our Skincare Specialists to perfectly complement your order.
Loyalty Rewards: La Crem Points
Earn La Crème Points with every purchase and redeem them for future orders. From time to time, we also offer Free Gifts With Purchase (GWP) for select brands, but these are available only while supplies last.
At Loshen & Crem, we aim to deliver excellence at every step of your skincare journey, with care and a touch of elegance. Questions? Don’t hesitate to reach out—we’re always happy to assist!
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A final gesture of care, a whisper of radiance.
La Touche Finale
In this short video, discover how to apply your Biologique Recherche Finishing Serum, a precious step in your ritual that elevates your skin to its most refined state.
With just a few drops, pressed gently into the skin, your complexion is left silky, luminous, and perfectly sealed.






