Your routine
Biologique RechercheLe Grand Sérum
Why it fits
Our estheticians love Le Grand Sérum layered over La Grande Crème: 4 to 5 drops over the cream complete the full ritual, and you will find both together in Le Grand Coffret.
Biologique Recherche La Grande Crème
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Explore La Crem rewardsSkin showing visible signs of aging
One of Biologique Recherche's icons: a rich, comprehensive face cream for skin showing visible signs of aging, from fine lines and wrinkles to a loss of firmness and an uneven-looking complexion.
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Boutique details
Your Edmonton boutique.
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Let’s talk about your skin and what belongs in your routine.
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Shipping, on usRegular $149+ · Priority $249+ CAD
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Selected with care.
Biologique Recherche
La Grande Crème
Your ritual begins with the right choice.
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The skincare focus
An icon for the many visible signs of aging.
One of Biologique Recherche's icons: a rich, comprehensive face cream for skin showing visible signs of aging, from fine lines and wrinkles to a loss of firmness and an uneven-looking complexion.
Explore our ingredient glossaryBiologique Recherche
The formula, explained.
The ingredients behind this formula—and what they bring to your skin.
Paeonia Albiflora (Peony) Root Extract
A botanical extract included to help skin look plumper and more supple.
Camellia Sinensis Leaf Extract & Lepidium Sativum (Watercress) Sprout Extract
Botanical extracts included to help even the look of skin tone.
Sambucus Nigra (Elderflower) Flower Extract & Terminalia Catappa Leaf Extract
Botanical extracts included in the formula's firming complex.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Pairs beautifully.
Cleanse with the milk selected for your Skin Instant, apply the Lotion P50 selected for your Skin Instant, then your Quintessential Serums. Apply La Grande Crème, then finish with 4 to 5 drops of Le Grand Sérum over the cream. Wear sunscreen in the morning. These pairings are suggestions; your routine should be personalized to your Skin Instant.
Your routine
Biologique RechercheLe Grand Coffret
Why it fits
The closing steps of your routine: La Grande Crème as your cream, then Le Grand Sérum as the finishing serum on top.
Worth knowing
The finer details.
A closer look at your skin, your routine and what goes into the formula.
Biologique Recherche La Grande Crème
Biologique Recherche La Grande Crème is one of the brand's icons: a rich, comprehensive face cream for Skin Instants showing visible signs of aging, from fine lines and wrinkles to a loss of firmness and an uneven-looking complexion.
Its peptides, botanical extracts and nourishing butters help the skin look firmer, smoother and more lifted, while the complexion looks more even and more radiant. Peony root extract helps skin look plumper and more supple, tea and watercress extracts help even the look of skin tone, and shea butter and beeswax help nourish and soften the skin.
For the full ritual, finish with 4 to 5 drops of Le Grand Sérum over the cream. Because La Grande Crème helps even the look of skin tone, wear your daily sunscreen in the morning.
Why we love it
La Grande Crème covers many visible signs of aging at once: fine lines, firmness, contours and an uneven-looking tone. We love its rich, nourishing comfort and the way it pairs with Le Grand Sérum, layered over the cream for the full ritual. It contains peppermint and caraway oils, so if your skin is very reactive, we prefer to see you for a consultation first.
Benefits
- Helps reduce the look of fine lines and wrinkles
- Helps skin look firmer, with more defined-looking contours
- Helps fade the look of dark spots and even the look of skin tone
- Helps support the skin's moisture barrier
- Antioxidant ingredients help protect skin from environmental stressors
Best for
Skin showing visible signs of aging
Apply La Grande Crème first, then press 4 to 5 drops of Le Grand Sérum over it to finish the ritual.
How to use
- Use morning and/or evening.
- Apply after your Lait (cleansing milk), the Lotion P50 selected for your Skin Instant and your Quintessential Serums.
- Apply a small amount to the entire face, neck and décolleté.
- For the full ritual, finish with 4 to 5 drops of Le Grand Sérum over the cream.
- Wear your daily sunscreen in the morning. For external use only.
Full Ingredient List
WATER (AQUA), OCTYLDODECANOL, CETEARYL ALCOHOL, GLYCERYL STEARATE, BUTYLENE GLYCOL, GLYCERIN, PROPANEDIOL, ALCOHOL DENAT., UNDECANE, BUTYROSPERMUM PARKII (SHEA) BUTTER, PROPYLENE GLYCOL, CETEARETH-20, PENTAERYTHRITYL TETRASTEARATE, SORBITAN STEARATE, CERA ALBA (BEESWAX), CAMELLIA SINENSIS LEAF EXTRACT, PAEONIA ALBIFLORA ROOT EXTRACT, MIMOSA TENUIFLORA BARK EXTRACT, ONOPORDUM ACANTHIUM FLOWER/LEAF/STEM EXTRACT, VITIS VINIFERA (GRAPE) JUICE EXTRACT, JASMINUM GRANDIFLORUM (JASMINE) FLOWER EXTRACT, SAMBUCUS NIGRA FLOWER EXTRACT, TERMINALIA CATAPPA LEAF EXTRACT, SOY ISOFLAVONES, LEPIDIUM SATIVUM SPROUT EXTRACT, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, LACTOBACILLUS/WASABIA JAPONICA ROOT FERMENT EXTRACT, PICHIA ANOMALA EXTRACT, ACETYL HEXAPEPTIDE-8, PALMITOYL OLIGOPEPTIDE, PENTAPEPTIDE-48, PALMITOYL TETRAPEPTIDE-7, ALPHA-GLUCAN OLIGOSACCHARIDE, DECARBOXY CARNOSINE HCL, SODIUM LACTATE, TANNIC ACID, CARUM CARVI (CARAWAY) FRUIT OIL, MENTHA PIPERITA (PEPPERMINT) OIL, CETYL PALMITATE, COCOGLYCERIDES, LECITHIN, HYDROGENATED LECITHIN, MALTODEXTRIN, TOCOPHEROL, CARBOMER, TRIDECANE, POLYSORBATE 80, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, TRIETHANOLAMINE, PVP, DISODIUM EDTA, POLYACRYLATE CROSSPOLYMER-6, POLYSORBATE 20, T-BUTYL ALCOHOL, PHENOXYETHANOL, METHYLPROPANEDIOL, ETHYLHEXYLGLYCERIN, CAPRYLHYDROXAMIC ACID, PHENETHYL ALCOHOL, CAPRYLYL GLYCOL, SORBIC ACID, LIMONENE.
Frequently Asked Questions
Who is La Grande Crème for?
Skin Instants showing visible signs of aging, from fine lines and wrinkles to a loss of firmness and an uneven-looking complexion.
How do I use it with Le Grand Sérum?
Apply La Grande Crème first, then finish with 4 to 5 drops of Le Grand Sérum over the cream. You'll find both together in Le Grand Coffret.
Do I need sunscreen with it?
Yes. Because La Grande Crème helps even the look of skin tone, wear your daily sunscreen in the morning.
Is it suitable for very reactive skin?
It contains peppermint and caraway oils. If your skin is very reactive, please book a consultation with one of our estheticians first.
Does it contain fragrance ingredients?
Its ingredient list includes limonene, a fragrance component, along with peppermint and caraway oils. Check the full ingredient list if you are sensitive to fragrance ingredients.
Consultation & reactions
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
Shipping
For delivery and return information, view our policy.
Biologique Recherche La Grande Crème is one of the brand's icons: a rich, comprehensive face cream for Skin Instants showing visible signs of aging, from fine lines and wrinkles to a loss of firmness and an uneven-looking complexion.
Its peptides, botanical extracts and nourishing butters help the skin look firmer, smoother and more lifted, while the complexion looks more even and more radiant. Peony root extract helps skin look plumper and more supple, tea and watercress extracts help even the look of skin tone, and shea butter and beeswax help nourish and soften the skin.
For the full ritual, finish with 4 to 5 drops of Le Grand Sérum over the cream. Because La Grande Crème helps even the look of skin tone, wear your daily sunscreen in the morning.
Benefits
- Helps reduce the look of fine lines and wrinkles
- Helps skin look firmer, with more defined-looking contours
- Helps fade the look of dark spots and even the look of skin tone
- Helps support the skin's moisture barrier
- Antioxidant ingredients help protect skin from environmental stressors
How to use
- Use morning and/or evening.
- Apply after your Lait (cleansing milk), the Lotion P50 selected for your Skin Instant and your Quintessential Serums.
- Apply a small amount to the entire face, neck and décolleté.
- For the full ritual, finish with 4 to 5 drops of Le Grand Sérum over the cream.
- Wear your daily sunscreen in the morning. For external use only.
Ingredients
WATER (AQUA), OCTYLDODECANOL, CETEARYL ALCOHOL, GLYCERYL STEARATE, BUTYLENE GLYCOL, GLYCERIN, PROPANEDIOL, ALCOHOL DENAT., UNDECANE, BUTYROSPERMUM PARKII (SHEA) BUTTER, PROPYLENE GLYCOL, CETEARETH-20, PENTAERYTHRITYL TETRASTEARATE, SORBITAN STEARATE, CERA ALBA (BEESWAX), CAMELLIA SINENSIS LEAF EXTRACT, PAEONIA ALBIFLORA ROOT EXTRACT, MIMOSA TENUIFLORA BARK EXTRACT, ONOPORDUM ACANTHIUM FLOWER/LEAF/STEM EXTRACT, VITIS VINIFERA (GRAPE) JUICE EXTRACT, JASMINUM GRANDIFLORUM (JASMINE) FLOWER EXTRACT, SAMBUCUS NIGRA FLOWER EXTRACT, TERMINALIA CATAPPA LEAF EXTRACT, SOY ISOFLAVONES, LEPIDIUM SATIVUM SPROUT EXTRACT, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, LACTOBACILLUS/WASABIA JAPONICA ROOT FERMENT EXTRACT, PICHIA ANOMALA EXTRACT, ACETYL HEXAPEPTIDE-8, PALMITOYL OLIGOPEPTIDE, PENTAPEPTIDE-48, PALMITOYL TETRAPEPTIDE-7, ALPHA-GLUCAN OLIGOSACCHARIDE, DECARBOXY CARNOSINE HCL, SODIUM LACTATE, TANNIC ACID, CARUM CARVI (CARAWAY) FRUIT OIL, MENTHA PIPERITA (PEPPERMINT) OIL, CETYL PALMITATE, COCOGLYCERIDES, LECITHIN, HYDROGENATED LECITHIN, MALTODEXTRIN, TOCOPHEROL, CARBOMER, TRIDECANE, POLYSORBATE 80, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, TRIETHANOLAMINE, PVP, DISODIUM EDTA, POLYACRYLATE CROSSPOLYMER-6, POLYSORBATE 20, T-BUTYL ALCOHOL, PHENOXYETHANOL, METHYLPROPANEDIOL, ETHYLHEXYLGLYCERIN, CAPRYLHYDROXAMIC ACID, PHENETHYL ALCOHOL, CAPRYLYL GLYCOL, SORBIC ACID, LIMONENE.
Skin Reaction Policy
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
The care behind your order
From our boutique.
To your door.
A few helpful details, before your next delivery.
Track your order01 · Across Canada
A good thing, on its way.
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Collect in Edmonton.
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · A little reassurance
Here after checkout, too.
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Paeonia Albiflora (Peony) Root Extract
A botanical extract included to help skin look plumper and more supple.
Camellia Sinensis Leaf Extract & Lepidium Sativum (Watercress) Sprout Extract
Botanical extracts included to help even the look of skin tone.
Sambucus Nigra (Elderflower) Flower Extract & Terminalia Catappa Leaf Extract
Botanical extracts included in the formula's firming complex.
Acetyl Hexapeptide-8, Palmitoyl Tetrapeptide-7, Palmitoyl Oligopeptide & Pentapeptide-48
Peptides that help smooth the look of fine lines and wrinkles.
Vitis Vinifera (Grape) Juice Extract & Tocopherol
Antioxidant ingredients that help protect skin from environmental stressors.
Butyrospermum Parkii (Shea) Butter & Cera Alba (Beeswax)
Help nourish and soften the skin.
Curious about your ingredients?
Explore La Matière
A little guidance. A more considered routine.
Your skin.
Our attention.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book your consultation Just a product question? Ask us.Personal guidance, in Edmonton or online.
The care behind your care
A place in your routine.
A team in your corner.
From your first question to your next replenishment, there’s a real person here to help.
01 Make sense of what you already use
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our team02 Get to know your skin
Take our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting point03 Keep the conversation going
A question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Explore Biologique Recherche.
Find your place to begin.
Discover Biologique Recherche La Grande Crème at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Biologique Recherche collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
A little care, to keep.
Your ritual, beautifully noted.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. A little reminder, with your team still in reach.