{"product_id":"volumizing-macro-ha-serum","title":"Volumizing macro ha serum","description":"\u003cp data-start=\"56\" data-end=\"513\"\u003eA next-generation hyaluronic acid serum designed to visibly restore volume, redefine facial contours, and improve overall skin quality. Powered by proprietary HYAsync technology, this advanced formula binds hyaluronic acid with alpha-lipoic acid to help protect, deliver, and sustain hydration within the skin. The result is a complexion that appears fuller, smoother, and more structurally supported over time—without relying on superficial plumping alone.\u003c\/p\u003e\n\u003cp data-start=\"515\" data-end=\"644\"\u003eThis is not just hydration. It’s structural support for skin that is beginning to show volume loss, laxity, and textural changes.\u003c\/p\u003e\n\u003ch5 data-start=\"646\" data-end=\"866\"\u003eRecommended for:\u003c\/h5\u003e\n\u003cul\u003e\n\u003cli data-start=\"646\" data-end=\"866\"\u003eSkin experiencing volume loss or early sagging\u003cbr data-start=\"716\" data-end=\"719\"\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"646\" data-end=\"866\"\u003eFine lines and loss of facial definition\u003cbr data-start=\"761\" data-end=\"764\"\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"646\" data-end=\"866\"\u003eDull, uneven texture and lack of radiance\u003cbr data-start=\"807\" data-end=\"810\"\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"646\" data-end=\"866\"\u003eAll skin types, including dehydrated and mature skin\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5 data-start=\"868\" data-end=\"1234\"\u003eBenefits:\u003c\/h5\u003e\n\u003cul\u003e\n\u003cli data-start=\"868\" data-end=\"1234\"\u003eVisibly plumps and restores the look of fullness\u003cbr data-start=\"933\" data-end=\"936\"\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"868\" data-end=\"1234\"\u003eHelps redefine facial contours, especially in the lower face\u003cbr data-start=\"998\" data-end=\"1001\"\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"868\" data-end=\"1234\"\u003eImproves skin texture, smoothness, and radiance\u003cbr data-start=\"1050\" data-end=\"1053\"\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"868\" data-end=\"1234\"\u003eSupports long-lasting hydration by protecting HA from degradation\u003cbr data-start=\"1120\" data-end=\"1123\"\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"868\" data-end=\"1234\"\u003eReduces the appearance of fine lines over time\u003cbr data-start=\"1171\" data-end=\"1174\"\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"868\" data-end=\"1234\"\u003eStrengthens the skin barrier and overall skin resilience\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5 data-start=\"1236\" data-end=\"1463\"\u003eHow to use:\u003c\/h5\u003e\n\u003cul\u003e\n\u003cli data-start=\"1236\" data-end=\"1463\"\u003eApply 1–2 pumps to clean, dry skin\u003c\/li\u003e\n\u003cli data-start=\"1236\" data-end=\"1463\"\u003eUse morning and evening\u003c\/li\u003e\n\u003cli data-start=\"1236\" data-end=\"1463\"\u003eApply to the entire face, avoiding the eye area\u003cbr data-start=\"1369\" data-end=\"1372\"\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"1236\" data-end=\"1463\"\u003eAllow to fully absorb before layering other products\u003c\/li\u003e\n\u003cli data-start=\"1236\" data-end=\"1463\"\u003eFollow with \u003ca href=\"https:\/\/www.loshen.ca\/collections\/sun-protection\" title=\"Sun Protection Canada\" rel=\"noopener\" target=\"_blank\"\u003eSPF\u003c\/a\u003e during the day\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5 data-end=\"18\" data-start=\"0\"\u003eClinical Study:\u003c\/h5\u003e\n\u003cp data-end=\"210\" data-start=\"20\"\u003eA single-center, dermatologist-led clinical study was conducted by \u003cspan class=\"hover:entity-accent entity-underline inline cursor-pointer align-baseline\"\u003e\u003cspan class=\"whitespace-normal\"\u003eSkinbetter Science\u003c\/span\u003e\u003c\/span\u003e to evaluate the performance of Ampra Volumizing Macro HA Serum when used twice daily.\u003c\/p\u003e\n\u003cp data-end=\"540\" data-start=\"212\"\u003eThe study included 65 women aged 45–65 presenting with mild to moderate signs of skin aging, including fine lines, uneven texture, visible sagging, and loss of radiance. Over a 12-week period, participants incorporated the serum into a controlled skincare routine to ensure results reflected the true performance of the formula.\u003c\/p\u003e\n\u003cp data-end=\"899\" data-start=\"542\"\u003eTo preserve the integrity of the study, participants completed a structured washout period prior to enrollment. This included discontinuing active skincare such as exfoliating acids (AHAs\/BHAs), antioxidants, vitamin C, peptides, and non-prescription retinoids for 4 weeks, and prescription-strength topicals such as tretinoin and hydroquinone for 4 months.\u003c\/p\u003e\n\u003cp data-end=\"1230\" data-start=\"901\"\u003eBefore beginning the study, participants followed a standardized 2-week skincare reset using only a gentle cleanser (morning and evening), a moisturizer (morning and evening), and SPF (morning). This baseline routine was maintained throughout the duration of the study to ensure results were not influenced by external variables.\u003c\/p\u003e\n\u003cp data-is-only-node=\"\" data-is-last-node=\"\" data-end=\"1384\" data-start=\"1232\"\u003eThis level of control matters. It allows us to look at the results and understand what the formula is truly capable of—on its own, without interference.\u003c\/p\u003e\n\u003ch5 data-end=\"1384\" data-start=\"1232\"\u003eBefore and After:\u003c\/h5\u003e\n\u003cp data-is-only-node=\"\" data-is-last-node=\"\" data-end=\"1384\" data-start=\"1232\"\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0088\/2527\/4447\/files\/PDP_Ampra_BA_Results_1208x800_1.webp?v=1775066025\"\u003e\u003c\/p\u003e\n\u003cp data-is-only-node=\"\" data-is-last-node=\"\" data-end=\"1384\" data-start=\"1232\"\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0088\/2527\/4447\/files\/PDP_Ampra_BA_Results_1208x800_2.webp?v=1775066026\"\u003e\u003c\/p\u003e\n\u003cp data-end=\"210\" data-start=\"20\"\u003e \u003c\/p\u003e\n\u003ch5 data-start=\"1465\" data-end=\"1911\"\u003eLoshen \u0026amp; Crem recommendation:\u003c\/h5\u003e\n\u003cp data-start=\"1465\" data-end=\"1911\"\u003e\u003cbr data-start=\"1497\" data-end=\"1500\"\u003eThis is the type of formula we reach for when hydration alone is no longer enough. If your skin is starting to feel less “supported” or you’re noticing subtle changes in contour, this is where you elevate your routine. Pair it with \u003ca href=\"https:\/\/www.loshen.ca\/collections\/barrier-enhancing-skin-care\" title=\"barrier support skincare\" rel=\"noopener\" target=\"_blank\"\u003ebarrier-supporting creams \u003c\/a\u003eand consistent SPF to protect the results you’re building. Ideal post-treatment or during seasonal transitions when skin needs deeper structural support.\u003c\/p\u003e\n\u003ch5 data-start=\"1913\" data-end=\"2570\"\u003eIngredients:\u003c\/h5\u003e\n\u003cul\u003e\n\u003cli data-start=\"1913\" data-end=\"2570\"\u003e\n\u003cstrong data-start=\"1943\" data-end=\"1979\"\u003eHYAsync (HA + Alpha-Lipoic Acid)\u003c\/strong\u003e: Enhances delivery and protects hyaluronic acid for longer-lasting hydration and activity\u003cbr data-start=\"2069\" data-end=\"2072\"\u003e\u003cstrong data-start=\"2074\" data-end=\"2124\"\u003e\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"1913\" data-end=\"2570\"\u003e\n\u003cstrong data-start=\"2074\" data-end=\"2124\"\u003eHydrolyzed Yeast Extract + Polyglucuronic Acid\u003c\/strong\u003e: Biofermented complex that supports hydration, smoothness, and visible lifting\u003cbr data-start=\"2203\" data-end=\"2206\"\u003e\u003cstrong data-start=\"2208\" data-end=\"2250\"\u003e\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"1913\" data-end=\"2570\"\u003e\n\u003cstrong data-start=\"2208\" data-end=\"2250\"\u003eHydrolyzed Eragrostis Tef Seed Extract\u003c\/strong\u003e: Supports collagen and elasticity for firmer-looking skin\u003cbr data-start=\"2308\" data-end=\"2311\"\u003e\u003cstrong data-start=\"2313\" data-end=\"2340\"\u003e\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"1913\" data-end=\"2570\"\u003e\n\u003cstrong data-start=\"2313\" data-end=\"2340\"\u003ePalmitoyl Tripeptide-38\u003c\/strong\u003e: Targets the extracellular matrix to improve plumpness and smoothness\u003cbr data-start=\"2410\" data-end=\"2413\"\u003e\u003cstrong data-start=\"2415\" data-end=\"2430\"\u003e\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"1913\" data-end=\"2570\"\u003e\n\u003cstrong data-start=\"2415\" data-end=\"2430\"\u003eNiacinamide\u003c\/strong\u003e: Strengthens the skin barrier and improves tone and resilience\u003cbr data-start=\"2493\" data-end=\"2496\"\u003e\u003cstrong data-start=\"2498\" data-end=\"2526\"\u003e\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"1913\" data-end=\"2570\"\u003e\n\u003cstrong data-start=\"2498\" data-end=\"2526\"\u003eSqualane + Jojoba Esters\u003c\/strong\u003e: Reinforce hydration and barrier function\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-start=\"2572\" data-end=\"3139\"\u003e\u003cstrong data-start=\"2572\" data-end=\"2590\"\u003efull inci list\u003c\/strong\u003e\u003cbr data-start=\"2590\" data-end=\"2593\"\u003eAqua\/Water\/Eau, Glycerin, Isocetyl Stearoyl Stearate, Niacinamide, Pentylene Glycol, Jojoba Esters, Hydrolyzed Yeast Extract, Squalane, Glycol Palmitate, Cetyl Alcohol, Lecithin, Sodium Methyl Stearoyl Taurate, Sodium Thioctoyl\/Formoyl Hyaluronate, Palmitoyl Tripeptide-38, Hydrolyzed Eragrostis Tef Seed Extract, Hydrolyzed Sodium Hyaluronate, Hydroxypropyl Cyclodextrin, Tetrasodium Glutamate Diacetate, Citric Acid, Xanthan Gum, Polyglucuronic Acid, Cetyl Hydroxyethylcellulose, Tocopherol, Potassium Sorbate, Sodium Benzoate, Phenoxyethanol\u003c\/p\u003e\n\u003cp data-start=\"3141\" data-end=\"3250\"\u003e \u003c\/p\u003e","brand":"SkinBetter Science","offers":[{"title":"30 ml","offer_id":48177286480120,"sku":null,"price":220.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0088\/2527\/4447\/files\/AmpraVolumizingMacroHASerum.png?v=1775065931","url":"https:\/\/www.loshen.ca\/products\/volumizing-macro-ha-serum","provider":"Loshen \u0026 Crem","version":"1.0","type":"link"}